Student Profile (Compulsory to fill, time allowed 10 minutes) Name: _______________________________ Date of birth: _______________________ Father’s Name: _________________________ Occupation: _________________________ Landline number: _______________________ Mobile number: ______________________ Permanent address: __________________________________________________________________________ College/ University: _________________________________________________________ CGPA/ Percentage in B.pharma: _______________________________ Appeared previously in GPAT (YES/ NO) Done any coaching as far? (YES/NO) Specify name if YES and duration How much you like to credit, out of 10 for your current GPAT preparation_________ Below is a “subject preparation analysis” data, students need to answer with Yes/ No in respective columns. Subject Pharmaceutics Biopharmaceutics Phamacology Pharmacognosy Pharmaceutical Analysis Pharmaceutical Microbiology Pharmaceutical Biochemistry Pharmaceutical Jurisprudence Strong Average 1 Weak COMMUNTIY PHARMACIST AID-CPA SCREENING TEST (CPAST-2015) INSTRUCTIONS: There are 30 questions in this paper Each question carries 4 marks, and for every wrong answers -1. There are four options, choose one and write it in your answer sheet/MS word doc, and submit it before provided time. To get accurate status of your preparation, you must solve it with yourself without any cheating. If a candidate fails to submit the answers before provided time, then he/she may be declared as disqualified. Results will declare on 10 August, 2014 at our website. According to cut-off marks, merit list will be generate Shortlisted students will be eligible to get indulged in CPA’s four months Rapid revision program. This test is free of cost ENTER YOUR ENROLLMENT NUMBER 2 General instructions: To answer the question, write options A/ B/ C/ D below the question, space provided To leave the question, don’t write anything No multiple answers need to write, if, so, negative marking will be there for such answers Do not write/ mark anything in paper, if, so, candidates will be disqualified At the end of paper, don’t forgot to give your feedback and experience All the best CPAST - 2015 Duration: 40 minutes Q1. “Indian Pharmacopoeia 2014” was released by: A. B. C. D. Mr. Ghulam Nabi Azad Ms. Sushma sawaraj Mr. Arun Jaitley Mr. Nitin Gadkari Answer: Q2. Which of the following dosage forms contain a mixture of oil and water? A. B. C. D. Elixirs Emulsions Suspension Ointment Answer: Q3. Which Hardness tester works on principle of Hydraulic pressure? A. B. C. D. Schleuniger tester Monsanto Pfizer Erweka Answer: Q4. One of the following is known as “Dummy medicine”, identify the right one A. B. C. D. Drugs during Phase-II of clinical trial Controlled released drug delivery system Suppositories Placebos 3 Q5. Cuferron is used as:- A. B. C. D. Chelating agent Indicator Precipitating agent Disintegrating agent Answer: Q6. The compound NOT assayed by “Complexometric Titration” is _______ A. B. C. D. Progesterone Injection Magnesium trisilicate Calcium lactate Sodium calcium edentate Answer: Q7. What would 10°C be in F? A. B. C. D. 50°F 17°F 77°F 102°F Answer: Q8. The storage requirements on the label read: Store at 1.5°C - 3.3°C. Where would you store them? A. B. C. D. Room temperature Freezer Refrigerator Incubator Answer: Q9. Which of the following NSAID drugs is classified as a COX-2 Inhibitor? A. B. C. D. Naproxen Celecoxib Ibuprofen Nabumetone Answer: Q10. Magnesium stearate is a A. B. C. D. Anti-adherant Glidant Lubricant Diluents Answer: 4 Q11.Which one of the following is a universal developing agent in TLC? A. B. C. D. Picric Acid Potassium Permanganate Sulphuric Acid Chromic Acid Answer: Q12. “5HT3” is an example of which type of receptor? A. B. C. D. Gpcr Ligand gated Nuclear Enzymatic Answer: Q13. Interaction that occurs between the fundamental vibrations and overtones/ combination tone vibration is known as ____ A. B. C. D. Fermi resonance Coupled interactions Stretching vibrations Bending vibrations Answer: Q14. The IUPAC name of penicillin is A. (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1azabicyclo[3.2]heptane-2-carboxylic acid B. (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(4-phenylacetamido)-4-thia-1azabicyclo[3.2]heptane-2-carboxylic acid C. (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(4-phenylacetamido)-4-thia-1azabicyclo[3.2.0]heptane-2-carboxylic acid D. (2S,5R,6R)-3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-1azabicyclo[3.2.0]heptane-2-carboxylic acid Answer: Q15. Choose the correct source of radiation for NMR A. B. C. D. Klystron oscillator Globar source Radio frequency oscillator Deuterium Lamp Answer: 5 Q16. Dug-Bin effect is related to: A. B. C. D. Tablet Capsule Chewable tablets Transdermal patches Answer: Q17. “Anethum graveolens” is a biological source of ___ A) B) C) D) Squill Dill Fennel Piplamul Answer: Q18. What reagents could be used to synthesize “Pindolol”? a) b) c) 6 d) Answer: Q19. Which of the following polymer will be most effective in controlling drug release of highly water soluble drug? A. B. C. D. Ethyl cellulose+ HPMC E RSPO+ Hydrogenated castor oil E RLPO + Hydrogenated castor oil HPMC + HPC Answer: Q20. Which of the following drugs have common side effects that include nausea and vomiting, excessive growth of body hair and gum tissue, ataxia and sedation? A. B. C. D. Diazepam Amoxicillin Allopurinol Phenytoin Answer: Q21. What is the measure of a drug's effectiveness called? A. B. C. D. Availability Bioequivalence Efficacy Potency Answer: Q22. Duration of action can be extended for days and sometimes up to year but once administered, the drug cannot be easily removed, identify the drug delivery system. A. B. C. D. Parenteral Controlled-release system Ocular drug delivery system Intranasal drug delivery system Intravaginal and intrauterine drug delivery system Q23. The term bioavailability is defined as ____________ 7 Answer: A. Drug substance in two dosage forms, reaches the systemic circulation at the same relative rate and to the same relative extent B. It compares drug products with respect to a specific characteristics to a defined set of standards C. Rate and extent of absorption of unchanged drug from its dosage form D. Systemic availability of a drug administered orally is determined in comparison to its intravenous administration. Answer: Q24. The maximum volume for an intradermal injection is ________. A. 2mL B. 1mL C. 5mL D 0.1ML Answer: Q25 If the %compressibility of powder is 10, and Hausners ratio equal to 1.10, what is the flow property: A. B. C. D. Excellent Very good Good Poor Answer: Matching Section Q26. Match the following “Acetylcholine receptors” with their respective locations in the body: Acetylcholine receptors A. B. C. D. locations M1 M2 (α7)5 (α1)2β1δε i) Skeletal neuromuscular junction ii) Cardiac iii) neural iv) Brain regions Answer: 8 Q27. Match the following “Detectors” with their respective analytical instruments: Instrument Detector A. Ultraviolet i) Photomultiplier tube B. Infrared ii) Photodiode C. Mass spectrometry iii) Bolometer D. Flame photometry iv) Faraday cup Answer: Q28. Match the following “Excipients” with its category used in tablet formulation: Excipients A. B. C. D. Category Liquid paraffin Stearic acid Aerosil PVP i) Glidants ii) Fluid lubricant iii) Disintegrants iv) Boundary lubricant Answer: Q29. State true (T) or False (F) i) ii) iii) iv) Amorphous forms of API will show Polymorphism. (T/F) Generic drugs can be marketed after filling AND to the FDA. (T/F) HCL is water soluble in strong acid. (T/F) In analytical equipments detectors are selected on the basis of bulk property and solute. (T/F) Q30. In 2010, a drug withdrawn from market due to “Risk of heart attack & death” was ____ A. B. C. D. Alosteron Rosiglitazone Efalizumab Dexfenfluramine Answer: ******************************All the best************************************* 9 Provide us your feedback and experience regarding paper: Questions were Simple/ Tough/ Reasoning Duration provided for examination was sufficient or less? Question pattern was excellent or poor? Is CPAST paper seems to be valuable to know your current preparation status? How much would you like to rate this paper out of 10? ---------------------------------------------For Evaluator use only------------------------------------------ Evaluator Marking Evaluator Evaluator 1 Evaluator 2 Q1-15 Marks Q15-30 Marks 10 Negative marks Total Marks