October 5, 2015: Morning Session Obesity, Metabolism, and the Lung 8:00 – 9:00 Evangelos Michelakis, MD The Interface Between Metabolism and the Pulmonary Vasculature University of Alberta 9:00 – 9:45 Janice B. Allen, Ph.D. The Emerging Role of Environmental Exposures in the Obesity/Asthma Axis National Institute of Environmental Health Sciences Break 10:15 – 11:00 Kelan Tantisira, MD Circulating miRNA in Asthma and Obesity Harvard Medical School 11:00 – 11:45 Benjamin Marsland, PhD Implication of Host-Microbe Interactions in Development of Respiratory Diseases University of Lausanne 11:45 – 12:30 Stephanie Shore, PhD Obesity and Asthma: Microbiome-Metabolome Interactions Harvard School of Public Health Lunch (12:30 – 1:30) 1 October 5, 2015: Afternoon Session Obesity and Airway Disease 1:30 – 2:10 Meredith McCormack, MD Obesity, Diet and Airway Disease Johns Hopkins University 2:10 – 2:50 Deepa Rastoogi, MD Metabolic Dysregulation and Pediatric Obesity-Related Asthma Albert Einstein College of Medicine 2:50 – 3:30 Fernando Holguin, MD Obesity, Metabolic Dysregulation and Airway Oxidative Stress University of Pittsburgh Break 3:50 – 4:30 Jason Bates, PhD The Mechanical Consequences of Obesity on Airways Responsiveness University of Vermont 4:30 – 5:10 Anne Dixon, MA BM BCh Phenotypes of Asthma in Obesity University of Vermont 2 October 6, 2015: Morning Session Mitochondria and Metabolism in Lung Disease I 8:00 – 8:45 Manu Jain, MD Mitochondrial Reactive Oxygen Species Regulate TGF-β Signaling Northwestern University Feinberg School of Medicine 8:45 – 9:00 Selected Abstract Talk 9:00 – 9:45 Stephen Black, PhD Role of the Mitochondrion in Pulmonary Vascular Disease Georgia Regents University Break 10:15 – 11:00 Augustine Choi, MD Mitochondrial Dysfunction: Regulator of Inflammation and Cell Death in Lung Disease Weill Cornell Medical College 11:00 – 11:15 Selected Abstract Talk 11:15 – 12:00 Ana Mora, MD Dysfunctional Mitochondria in Lung Fibrosis University of Pittsburgh Lunch (12:00 – 1:00) 3 October 6, 2015: Afternoon Session Mitochondria and Metabolism in Lung Disease II 1:00-1:15 Selected Abstract Talk 1:15 – 2:00 Viswanathan Natarajan, PhD Lysocardiolipin, a Mitochondrial Cardiolipin Remodeling Enzyme, in the Pathogenesis of Pulmonary Fibrosis University of Illinois at Chicago 2:00 – 2:45 Abstract Talk Poster Discussion and Reception (2:45 – 5:00) 4 October 7, 2015: Morning Session Lipid Handling and Mishandling: Effects on Lung Inflammation and Remodeling 8:00 - 8:40 Benjamin Suratt, MD Hypercholesterolemia and the ‘Priming’ of the Lung for Disease University of Vermont College of Medicine 8:40 - 9:20 Ross Summer, MD Dysregulated Lipid Synthesis Promotes Fibrotic Responses in the Lung Thomas Jefferson University 9:20 - 10:00 Michael Fessler, MD A Novel Role for Oxysterols in Resolution of Lung Inflammation and Critical Illness National Institute of Environmental Health Sciences Break 10:20 - 11:00 Yury Miller, MD, PhD Targeted Cholesterol Efflux and Inflammation University of California, San Diego 11:00 – 11:40 Konstantin Birukov, MD, PhD Oxidized Phospholipids in Lung Injury and Inflammation: Friend or Foe? The University of Chicago 11:40 – 12:20 Irina Petrache, MD Metabolic Derangements in COPD National Jewish Health Lunch & Conference Summary (12:20 – 1:20) 5