October 5, 2015: Morning Session Obesity, Metabolism, and the

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October 5, 2015: Morning Session
Obesity, Metabolism, and the Lung
8:00 – 9:00
Evangelos Michelakis, MD
Metabolic Theory of Pulmonary Hypertension
University of Alberta
9:00 – 9:45
Janice B. Allen, Ph.D.
The Emerging Role of Environmental Exposures in the Obesity/Asthma
Axis
National Institute of Environmental Health Sciences
Break
10:15 – 11:00
Kelan Tantisira, MD
Circulating miRNA in Asthma and Obesity
Harvard Medical School
11:00 – 11:45
Benjamin Marsland, PhD
Implication of Host-Microbe Interactions in Development of Respiratory
Diseases
University of Lausanne
11:45 – 12:30
Stephanie Shore, PhD
Obesity and Asthma: Microbiome-Metabolome Interactions
Harvard School of Public Health
Lunch (12:30 – 1:30)
1
October 5, 2015: Afternoon Session
Obesity and Airway Disease
1:30 – 2:10
Meredith McCormack, MD
Obesity, Diet and Airway Disease
Johns Hopkins University
2:10 – 2:50
Deepa Rastogi, MD
Metabolic Dysregulation and Pediatric Obesity-Related Asthma
Albert Einstein College of Medicine
2:50 – 3:30
Fernando Holguin, MD
Obesity, Metabolic Dysregulation and Airway Oxidative Stress
University of Pittsburgh
Break
3:50 – 4:30
Jason Bates, PhD
The Mechanical Consequences of Obesity on Airways Responsiveness
University of Vermont
4:30 – 5:10
Anne Dixon, MA BM BCh
Phenotypes of Asthma in Obesity
University of Vermont
2
October 6, 2015: Morning Session
Mitochondria and Metabolism in Lung Disease I
8:15 – 9:00
Manu Jain, MD
Mitochondrial Reactive Oxygen Species Regulate TGF-β Signaling
Northwestern University Feinberg School of Medicine
9:00 – 9:45
Stephen Black, PhD
Role of the Mitochondrion in Pulmonary Vascular Disease
Georgia Regents University
Break
10:15 – 11:00
Augustine Choi, MD
Mitochondrial Dysfunction: Regulator of Inflammation and Cell Death in
Lung Disease
Weill Cornell Medical College
11:00 – 11:45
Ana Mora, MD
Dysfunctional Mitochondria in Lung Fibrosis
University of Pittsburgh
Lunch (11:45 – 1:00)
3
October 6, 2015: Afternoon Session
Mitochondria and Metabolism in Lung Disease II
1:00 – 1:45
Viswanathan Natarajan, PhD
Lysocardiolipin acyltransferase, a mitochondrial cardiolipin remodeling
enzyme, in the pathogenesis of pulmonary fibrosis
University of Illinois at Chicago
Effects of Obesity on Airway Inflammation and Asthma
2:00 – 2:15
2:15-2:30
2:30-2:45
2:45-3:00
Obesity Modulates the Alveolar Macrophage Response
(NDJ Ubags, AM Wallace, S Ventrone, E Dilli, M Antkowiak, SC Frasch, DL
Bratton, EFM Wouters, BT Suratt
Obesity -related airway hyperresponsiveness is regulated by endothelin-1
in mice
(David I. Kasahara, Norah G. Verbout, Stephanie A. Shore)
The Bronchodilatory Effects of Beta-Agonist and Weight Loss are Similar
in Severely Obese Patients After Bariatric Surgery
(Ubong Peters, Paul Hernandez, Gail Dechman, Jim Ellsmere, Geoff
Maksym)
Obesity and leptin modulate airway eotaxin and MMP-9 production in
allergic mice and patients with asthma
(Jennifer L. Ingram, Jasmine Weiss, R. Wesley Sigmon, Akhil Hegde,
Barbara Theriot, Michael Ghio, Jordan Wong, Njira Lugogo, Loretta Que,
Julia Walker, Monica Kraft)
Poster Discussion and Reception (5:00 – 6:00)
4
October 7, 2015: Morning Session
Lipid Handling and Mishandling: Effects on Lung Inflammation and Remodeling
8:00 - 8:40
Benjamin Suratt, MD
Hypercholesterolemia and the ‘Priming’ of the Lung for Disease
University of Vermont College of Medicine
8:40 - 9:20
Ross Summer, MD
Dysregulated Lipid Synthesis Promotes Fibrotic Responses in the Lung
Thomas Jefferson University
9:20 - 10:00
Michael Fessler, MD
A Novel Role for Oxysterols in Resolution of Lung Inflammation and
Critical Illness
National Institute of Environmental Health Sciences
Break
10:20 - 11:00
Yury Miller, MD, PhD
Targeted Cholesterol Efflux and Inflammation
University of California, San Diego
11:00 – 11:40
Konstantin Birukov, MD, PhD
Oxidized Phospholipids in Lung Injury and Inflammation: Friend or Foe?
The University of Chicago
11:40 – 12:20
Irina Petrache, MD
Metabolic Derangements in COPD
National Jewish Health
Lunch & Conference Summary (12:20 – 1:20)
5
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