Pilot grant application, 2016 Pilot grant application 2016 Stichting MS Research P.O. Box 200 2250 AE Voorschoten The Netherlands E-mail : onderzoek@msresearch.nl Tel. : +31-71-5 600 500 or +31-71-5 600 508 (research coordinator) Our project number: 16 – .... MS Please send an electronic version (Word-file) and 1 signed hard copy to the addresses above Please use arial 10, single line spacing Extra attachments will not be accepted Basic details 1 2 3 4 5 Name applicant, title(s) Position Institute Department Postal address Zip code, city Telephone E-mail Title proposed project English Dutch Brief summary of research question and study design (300 words max.) Host institution (if applicable) Relevance for MS Mr/Ms, Prof./Dr. Research proposal 6 Background & research questions Background (500 words) Hypothesis (100 words) Objectives (100 words) Pilot/preliminary data if applicable (200 words) Max. 25 references Supplemental information is not allowed 1 Pilot grant application, 2016 7 8 9 10 11 12 Study design & work plan (1000 words) Planning subsequent years (200 words and/or scheme) Project group (*fte involved in this project) Embedding & cooperation Relationship of this grant proposal with other studies financed by the Dutch MS Research Foundation Has this grant proposal been submitted to the Dutch MS Research Foundation previously? If yes: What was the project number of this proposal? What are the differences between this and the previously submitted application? Has this grant proposal been submitted elsewhere? Title(s) and name Discipline yes/no Human subjects, laboratory animals, biohazards 13 a. b. c. d. Will experiments be performed with: Patient material Healthy volunteers yes/no Patients yes/no If yes: Number of volunteers/patients Type of research Does the proposed study yes/no/requested have the approval of a commission regarding experimental subjects? Experimental animals Use of experimental animals yes/no If yes: Kind of animals Number of animals needed per year Nature of intervention Justification for the number of animals required Does the proposed study yes/no/requested have the approval of a commission regarding experimental animals? Brain material Use of brain material yes/no Biological risks Recombinant DNA yes/no If yes: Class Radiation (wave and/or yes/no particle) Radioactive isotopes yes/no Pathogenic micro-organisms yes/no Are required grants, permits yes/no and facilities available? 2 Employed by Fte* Pilot grant application, 2016 Finances and justification 14 15 Justification Personnel, expertise, discipline and time frame Materials and/or patients Other Financial support from sources other than the Dutch MS Research Foundation: Own institute Others Personnel and budget requested ** 16 17 Personnel Function Lump sum category (delete whichever is not applicable) Fte Amount of months Costs (€) Personnel Materials/patients Other: Scientific staff Technical staff promovendus/wetenschappelijk medewerker NWP niveau 1/niveau 2/niveau 3 Total costs (€) Signatures 18 Responsible administrator of organisation Project leader Name Signature ** According to the grant directives (2015) 3 Pilot grant application, 2016 Addendum Justification for the requirement of experimental animals * 21 a. b. c. What are the reasons that this research… …cannot be performed without experimental animals (Replacement)? …cannot be performed with fewer animals (Reduction) or with less distress and discomfort for the animals (Refinement)? …cannot be performed with a lower species of animals? Justification for the requirement of EAE animal models * 22 What are the reasons that this research requires the use of an EAE-animal model? * If the grant proposal does not require experimental animals, this addendum can be deleted from the application 4