1. 1. lack of blood plasma proteins and tissue fluid retention/abdominal bloating/swollen abdomen; 2. kwashiorkor/marasmus develops; 3. poor growth and development (among children); 4. (often) mental retardation; 5. lethargic/little interest in surroundings 6. wasting of muscle / thin muscles; 2. cause: [1 max] 1. a genetic variation/mutation; change in gene coding for tyrosine hydroxylase; consequences: [1 max] 2. results in a failure to metabolize phenylalanine into tyrosine; 3. results in high levels of ketones in the blood and urine; 4. results in mental retardation/brain damage; diagnosis: [1 max] 5. can be made by a simple blood test for the level of phenylalanine; 6. diagnosis can be made shortly after birth; 3 max [3] 3. 1. may lead to obesity (which is risk factor for many health problems); NOT weight gain 2. (obesity leads to) increased risk of coronary heart disease/gall bladder 3. disease/high blood pressure/diabetes/excess strain on joints; Accept CHD 4. may lead to increase in blood cholesterol/low density lipoprotein/LDL/ lipid levels; 5. deposits impede blood flow / cause diameter of blood vessel to decrease / atherosclerosis / degeneration of artery walls; 6. health consequences depend on type of fat ingested — high saturated fat; 3 max 4. (a) 1. e.g. cod liver oil / fish liver oil / oily fish (accept correctly 2. named example) / egg yolk / fortified cereal / ONE named 3. dairy product (i.e. milk/cheese/ yoghurt) Allow any two sources for the mark. Reject fish alone. IB Questionbank Biology 1 1 (b) 1. UV light/sunlight on skin causes chemical production of vitamin D; 2. UV too low in winter in high latitudes; 3. vitamin D stored in liver so can make enough to last severalmonths/through winter; 4. UV light can damage skin and cause skin cancer so exposure needs to be limited; 5. use of sun-block will inhibit vitamin D production; 6. covering skin with clothing prevents UV reaching skin; Accept reference to cultural/religious customs. 3 max 5. 1. There are cis-unsaturated (isomers) or trans-unsaturated (isomers fatty acids)/ cis-unsaturated hydrogen atoms are bonded on the same side of carbon-carbon double bond and trans the hydrogen atoms are bonded on the opposite side. ; 2. There are saturated or unsaturated fatty acids, saturated fatty acids have NO double bonds between carbon atoms and unsaturated have one or more double bonds between carbon atoms; 3. There are monounsaturated or polyunsaturated; 4. The difference between monounsaturated and polyunsaturated have to do with the location and the number of the double bonds between carbon atoms; 5. Fatty acids can have short chain or long chain; 6. (a) (b) minerals are usually elements whereas vitamins are compounds; minerals are inorganic while vitamins are organic; 2 iodine deficiency can lead to goitre / mental retardation; iodine is necessary for thryoxine production; dietary supplementation usually through iodized salt; cost to supplement is minimal but cost of deficiency is high; few foods rich in iodine / lack of marine food in diet can lead to deficiency; 3 max [5] IB Questionbank Biology 2 (a) (i) Asian [1] (ii) 11.5 (%) (allow answers in the range of 11 (%) to 12 (%)) [1] (NOTE: question is worded awkwardly but if students give both 24.5 % and 11.5 % do not give credit) (b) 1. all ethnic groups show range (very high, high and normal) of albumin levels; 2. greatest frequency of very high levels of albumin found in Pacific Islander patients/ European ancestry patients have lowest frequency of very high levels of albumin; 3. greatest frequency of high levels of albumin in Indigenous Australian/European ancestry patients / lowest frequency of high levels of albumin in Pacific Islander patients; 4. European ancestry patients have highest frequency of normal levels of albumin / Indigenous Australian/Pacific Islander patients have lowest frequency of normal levels of albumin; [3 max] (c) 1. European ancestry patients have highest/higher frequency of kidney failure but more than half/a large percentage have a normal level of albumin; 2. Indigenous Australian patients have lower frequency of kidney failure but higher levels of albumin; 3. it would be better to test for both kidney failure and albumin levels; [2 max] IB Questionbank Biology 3