Course Biology 30 Grade Level 12 Subject Nervous System Time Frame 89 minutes The Neuron Developed by Marcelle de Repentigny Lizotte Title Stage 1 – Desired Results Content Standard(s): This unit examines the biological processes that mediate the interactions between humans and their environment to maintain equilibrium. The nervous system contributes to homeostasis through its response to internal and external stimuli. Endocrine glands help to maintain homeostasis through the hormones they release into the blood. A study of the interactions between the nervous and endocrine systems leads to an examination of the functioning of the central and peripheral nervous systems and their ability to sense the environment and respond to it. General Outcomes: Students will explain how the nervous system controls physiological processes Knowledge objectives (outcomes): Students will . . . Describe the general structure and function of a neuron and myelin sheath, explaining formation and transmission of an action potential, including all-or-none response and intensity of response; the transmission of a signal across a synapse; and the main chemicals and transmitters involved, i.e., norepinephrine, acetylcholine and cholinesterase (A1.1k) Student Self-Assessments Working in pairs (peer evaluation) Essential Questions: 1) What are the different structures of the neuron and their function? 2) What three kinds of neurons are present in our bodies? Skill objectives (outcomes): Students will be able to . . . o Work collaboratively in addressing problems and apply the skills and conventions of science in communicating information and ideas, and in assessing results (A1.4s) Attitude objectives (outcomes): Students will be encouraged to… o Work collaboratively in planning and carrying out investigations and in generating and evaluating ideas Stage 2 – Assessment Evidence Other Evidence (assessments) Neuron craft with proper structures and functions labeled Stage 3 – Learning Plan Learning Activity: We are now starting the nervous system unit. In this introductory class, the basic functions of the nervous system, as well as the different structures of the neuron will be taught. What the Teacher does . . . What the Student does . . . Time Materials Give notes on nervous system, cells of the nervous system, neurons, grey/white matter and neuron diagram Go through notes with students, teaching about the purpose of the nervous system and the parts of the neuron. Display neuron diagram on smartboard and fill in the blanks in front of class Students receive notes 4 min Notes Follow notes and ask questions 30 min Notes Fill in the blanks on their diagram 5 min Diagram Neuron craft activity: - - Make groups of 2 Build 1 fully labeled neuron and attach to the wall Be sure to include the following structures and their function: o Dendrite o Axon o Schwann Cell o Nodes of Ranvier o Nucleus o Neurolemma o Cell Body o Axon Terminal o Myelin Sheath o Effector/Receptor Must put neuron on 8x11 paper Manage class Listen to directives 5 min Build neuron and hang on wall 45 min Stickers Sticky rhinestones Balloons Modeling clay Pompoms Pipe cleaners Pencil crayons Scissors Tape Straws String/yarn Hot glue guns Ribbon Wood skewers Beads Popsicle sticks 8x11 paper Rubric: Build-A-Neuron Names:______________________________________________________________________________ All structures are clearly and correctly labeled (dendrite, axon, Schwann cell, Nodes of Ranvier, nucleus, neurolemma, cell body, axon terminal, myelin sheath, effector/receptor) All functions are clearly and correctly displayed /5 /5 TOTAL /10 Your Nervous System - - Monitors and maintains a constant internal environment Monitors and responds to an external environment o Done by both the nervous system (electrochemical messages to the brain) and the endocrine system (hormones in the blood) Memory, learning and language are parts of your nervous system Three basic functions of the nervous system: 1. Receive sensory input form internal and external environment 2. Integrate the input 3. Respond to stimuli Sensory Input - Receptors sense changes in the environment o Including pressure, taste, sound, light, blood pH o These are converted to a signal (nerve impulse) and sent to the brain or spinal cord Integration - In the sensory centers of the brain or in the spinal cord, the barrage of input is integrated and a response is generated Response - A motor output (signal transmitted to organs where they can convert the signal into some form of action) o For example: movement, changes in heart rate, release or hormones Cells of the Nervous System 1. Glial (neuroglial) cells o Non conducting cells o Used for structural support and metabolism of neurons o Release calcium and glutamate, allowing neurons to communicate with one another o Insulate neurons and around synapses o 90% of the brain 2. Neurons o Functional unit of the nervous system o Three types (sensory neuron, interneuron, motor neuron) o 10% of the brain Sensory Neuron - INPUT - Relay information about the environment to the CNS for processing - E.g. What you see, changes in external temperature, a touch to the skin Interneuron - Link neurons within the body - Found mostly in the brain and spinal cord - Integrate and interpret the sensory information coming in and connect the neuron to an outgoing motor neuron Motor Neuron - OUTPUT - Relay information to the effectors (muscle, gland, and organ) that make things happen All Neurons Have… 1. Dendrites o Receive information from sensory receptors or motor neurons o Conduct impulses TOWARD the cell body 2. Cell body o Contains a nucleus, mitochondria, etc 3. Axon o Extension of the cytoplasm from cell body o Conducts impulses AWAY from the cell body o Can be up to 1 m in length o Extremely thin – 100 can fit in the width of 1 hair o Carries the nerve impulses towards other neurons or the effector (organ, gland, muscle about to work) o Can be covered by a fatty protein called the myelin sheath, which acts as an insulator for the neuron and prevents the loss of charged ions from the nerve cell (we say these nerves are myelinated) o Made up of Schwann cells o These cells are responsible for the production of the myelin sheath o The areas between the sections of myelin sheath are called nodes of Ranvier o Nerves of the peripheral nervous system also have a neurolemma o Thin membrane around the axon that allows neurons to regenerate (rejoin if cut) o This membrane activates Schwann cells White Matter vs. Grey Matter Two types of tissues in the central nervous system 1. White Matter o Neurons that contain a myelin sheath and neurolemma, giving them a white color o Provides communication between different areas of grey matter o 60% of your brain 2. Grey Matter o Neurons that do not have a myelin sheath and neurolemma, making them look grey o Does the actual processing o Cannot regenerate, any damage is permanent o 40% of your brain, but uses 94% of the oxygen supplied to your brain Multiple Sclerosis - Your body attacks the myelin sheath around the white matter in your brain, breaking it down and leaving hard plaques (like scars) behind. - When nerve messages are sent to the white matter, they get lost - Slows or blocks muscle coordination, visual sensation and other nerve signals