Bovine Deoxyribonuclease (DNase) – FAQ’s
Q: Where is the raw material sourced from?
Raw material is sourced from OIE (World Organisation for Animal Health) member countries
classed as negligible risk for BSE. The pancreas is harvested by certified establishments using
approved procedures. The importation and inspection of the pancreas is under the authority of the
South African Department of Agriculture Fisheries Forestry (DAFF) regulatory requirements.
Q: Is DNase produced from bovine and / or porcine raw material?
Deoxyribonuclease produced at BBI Solutions is extracted from bovine pancreas.
Q: Where is DNase manufactured?
DNase is extracted and purified at BBI’s class ISO9001:2008 bulk extraction facility in Cape Town,
South Africa. Final products are prepared and packaged in an ISO 8, Class 100,000 facility.
Q: Can the product specification be customised if we need any additional testing?
Yes, we can investigate the additional requirements and will profile this specification against our
current process capability. If product specification falls outside our process capability, the project
will be handled by our R&D department.
Q: What are the key features and benefits?

Guaranteed quality: DNase is manufactured under our Quality System compliant with ISO
9001:2008, with stringent QC analysis for every batch.

High Activity: Our DNase has been developed over 40 years ensuring optimal
performance and the highest quality.

Batch-to-batch reproducibility: Enabling consistent formulations.

EDQM approved: We maintain a Certificate of Suitability for TSE Risk Management issued
by the EDQM for materials derived from bovine raw material.

Bulk extraction capability: We are able to offer large volumes to your exact product
specification.

Secure supply: We have direct relationships with our raw material suppliers to ensure a
secure supply chain.

Cost effective: Bovine deoxyribonuclease offers a cost effective alternative to recombinant
products.
Q: What volume of material can I buy?
Product volume, lead times and availability can be discussed with our Account Management team.
Q: Is stability data available for materials supplied?
BBI has implemented a stability shelf-life program, which includes selected materials, and is
currently in progress. The program will be expanded to include all materials progressively. Stability
data is available for selected materials.
Q: Recommended Storage conditions?
We recommend you store the material at -20°C and temperatures during transport should remain
between 2 - 8°C.