Postdoctoral Researchers (2) - Genome Stability
Genome Stability Laboratory / Centre for Chromosome Biology
Biochemistry / School of Natural Sciences
Ref. No. NUIG-86-14
Applications are invited from suitably qualified candidates for two full-time fixed term positions as
Postdoctoral Researchers within the Genome Stability Laboratory of the Centre for Chromosome
Biology at the National University of Ireland, Galway. Funding is from a Science Foundation Ireland
Investigator Program Grant to Professor Noel Lowndes and is available from November 2014 for up
to 36 months.
These postdoctoral positions are available within the Genome Stability Laboratory
(http://www.chromosome.ie/researchers/lowndes/), a constituent laboratory of the Centre for
Chromosome Biology (http://www.chromosome.ie/) at the National University of Ireland Galway
(http://www.nuigalway.ie/index.html). The CCB is composed of 11 independent laboratories hosting
over 50 researchers, while NUI Galway boasts an active, vibrant student life with over 17,000
students and postdoctoral researchers from around the world.
The successful applicant will utilise biochemical and genetic approaches to understand the function
and mechanism of action of the PIK kinases, ATM and ATR, which perform crucial tumour
suppressive functions in the maintenance of genome stability. For two recent relevant publications
see Eykelenboom et al (2013) Cell Reports 2013 5(4): 1095-1107 and Pessina & Lowndes (2014)
PLoS Biol., 12, e1001856.
Job Description:
The successful candidates will be required to:
 Successfully analyse data, mange and develop their assigned projects
 Employ the latest gene targeting methodologies to for analysis of phenotype
 Utilise advanced biochemical methodologies to analyse ATM/ATR functions
 Develop advanced techniques in microscopy to analyse ATM/ATR functions
 Contribute to laboratory management
 Actively participate with the training of students
Qualifications/Experience of applicants.
The successful candidates will require:
 A PhD in Biochemistry, Cell Biology, Genetics or a cognate discipline
 A successful track record in relevant research as evidenced by peer reviewed publications in
highly ranked journals
 Evidence of self-directed capabilities in research
 Advanced experience in characterising the biological function and mechanism of action of
genes/proteins is essential
 Advanced experience in basic molecular cell biology, including basic biochemistry and
immunochemistry and molecular biology
Additional requirements for this post would include;
 Excellent communication and organizational skills
 Motivation and enthusiasm for their research
 Strong documentation, oral and interpersonal skills.
 Evidence of direct experience in the fields of genome stability and/or cell cycle regulation and
would be well placed to apply for independent personal fellowships.
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Salary: €37,750 - €46,255 per annum (public sector pay policy rules pertaining to new entrants will apply)
Start date: Position is available from November 2014
Further information on research and working at NUI Galway is available on Research at NUI Galway
For information on moving to Ireland please see www.euraxess.ie
Further information about the Centre for Chromosome Biology is available at: http://www.chromosome.ie/
and the discipline of Biochemistry at: http://www.nuigalway.ie/biochemistry/
(Informal enquiries concerning the post may be made to the project leader, Professor Noel Lowndes
(email: noel.lowndes@nuigalway.ie)
To Apply:
Applications to include a covering letter, CV, and the contact details of three referees should be sent,
via e-mail (in word or PDF only) to Professor Noel Lowndes (email: noel.lowndes@nuigalway.ie)
Note: It is essential to put reference number NUIG-86-14 in the subject line of e-mail applications.
Closing date for receipt of applications is 5.00 pm on Friday 10th October 2014.
National University of Ireland, Galway is an equal opportunities employer.
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