Conference on Reproduction & Regeneration Sponsored by Center

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Conference on Reproduction & Regeneration

Sponsored by Center for Research on Reproduction and Women’s Health,

Institute for Regenerative Medicine and Molecular Reproduction and Development

June 13-14, 2011

Translational Research Center

3400 Civic Center Boulevard

University of Pennsylvania

Conference will be held in the Auditorium

Monday AM: Regenerative Medicine/Stem Cell Session

8:30-9:00 Introductions: Drs. Driscoll, Gearhart and Gaulton

9:00-9:30 Randy Prather: The Multipotentiality of Pig Skin-Derived Stem Cells

9:30-10:00 Matthew Wheeler: Strategies for regeneration of the bone using porcine adult adipose-derived mesenchymal stem cells

10:00-10:15 Break

10:15-10:30 Xiaomin Zhong: Double-negative feedback loop between reprogramming factor LIN28 and microRNA in embryonic stem cells and tumor-initiating cells

10:45-11:00 Lee Kapp: A Novel Mutation Resulting in Loss of the Germline in

Zebrafish

11:00-11:30 Carmen Williams: Outside-in calcium signaling and mouse egg activation

11:30-12:00 Kyle Gurley: Functional Dissection of Planarian Tissue

Regeneration, Remodeling, and Homeostasis

12:00-1:00 Lunch (box lunch)

Monday PM: Regeneration/Stem Cell Session

1:00-1:30 Keith Latham: Spindle formation and function in cloned embryos

1:30-2:00 Vargheese Chennathukuzhi: The loss of REST and uterine fibroid pathogenesis

2:00-2:15 Elliott Abrams: Brambleberry, a novel nuclear envelope associated protein, acts in pronuclear fusion and cleavage stage development

2:15-2:30 Haixin Chang: Adenine nucleotides modulate mouse sperm flagellar movement patterns

2:30-2:45 Break

2:45-3:00 Stacie Dilks: Zfh-1 and Cellular Adhesion in the Drosophila Testis

Stem Cell Niche

3:00-3:30 Christopher Chen: Mechanical regulation of stem cells

3:30-4:00 Richard Schultz: Egg-to-embryo transition: a molecular perspective

4:00-5:15 Introduction and James M. Cuozzo lecturer-

5:15

Ralph Brinster: Male Germline Stem Cells and Fertility

Poster session and reception revised

6/4/11

1

Conference on Reproduction & Regeneration

Sponsored by Center for Research on Reproduction and Women’s Health,

Institute for Regenerative Medicine and Molecular Reproduction and Development

June 13-14, 2011

Translational Research Center

3400 Civic Center Boulevard

University of Pennsylvania

Conference will be held in the Auditorium

Tuesday AM: Gametes

8:30-9:00 Mary Lou King: Repression in Xenopus germline: Surprises in gene regulation

9:00-9:30 Patricia Martin-DeLeon: New players in the Calcium

“toolkit” and sperm motility

9:30-10:00 Keith Sutton: Sperm-oviduct interaction, the mechanisms of capacitation, and sperm polycystins

10:00-10:15 Break

10:15-10:30 Isaac Sasson: Distinguishing the effects of maternal obesity on the oocyte prior to pregnancy from effects of maternal obesity during gestation

10:30-10:45 Mirella L. Meyer-Ficca: Sperm Chromatin Composition is Regulated by Poly(ADP-Ribosyl)ation and Influences Early Embryonic Gene

Expression

10:45-11:00 Boram Kim: Role of MATER in Cytoplasmic Lattice Formation and

Organelle Redistribution During Oocyte Maturation

11:00-11:30 Dagmar Wachten: CRIS - a novel male germ-cell specific target for cyclic nucleotides involved in sperm function

11:30-12:00 Mariana Wolfner: Conserved and new roles for GLD2 cytoplasmic polyA polymerases in the germline: insights from Drosophila

12:00-1:00 Lunch (box lunch) and poster viewing

1:00-1:30 Willie Swanson: Adaptive Evolution and Coevolution of Sperm -

Egg Recognition Molecules

1:30-2:00 Jeremy Wang: Genetic causes of infertility in men

2:00-2:30 Gary Wessel: Mechanisms of multipotent cell determination in early development

2:45-5:00 Workshop revised

6/4/11

2

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