Jessica A. Alvarez, PhD, RD Page 1 CURRICULUM VITAE Revised: 07/30/2014 1. Name: JESSICA ALEJANDRA ALVAREZ, PHD, RD 2. Office Address: 101 Woodruff Circle NE WMRB 1028 Atlanta, GA 30329 (phone) 404-727-1549; (fax) 404-727-1300 3. Email address: jessica.alvarez@emory.edu 4. Citizenship: United States 5. ACADEMIC APPOINTMENTS: July 1, 2014 Instructor of Medicine, Division of Endocrinology, Metabolism and Lipids, Department of Medicine, Emory University School of Medicine 2011-present Postdoctoral Research Fellow, Division of Endocrinology, Metabolism and Lipids, Department of Medicine, Emory University School of Medicine 6. PREVIOUS ACADEMIC AND PROFESSIONAL APPOINTMENTS: 2007-2011 2005-2009 2005-2007 2005-2006 2004-2005 Nutrition Graduate Assistant, Department of Nutrition Sciences and General Clinical Research Center/ Participant and Clinical Interaction Resource, University of Alabama at Birmingham Laboratory Technician, General Clinical Research Center, University of Alabama at Birmingham Nutrition Research Trainee, General Clinical Research Center, University of Alabama at Birmingham Nutrition Graduate Trainee, Pediatric Pulmonary Center, University of Alabama at Birmingham Dietetic Intern, University of Alabama at Birmingham 7. EDUCATION: 1999-2004 BS, Dietetics Louisiana State University; Baton Rouge, LA Minor: Psychology Honors: Cum Laude 2004-2005 Registered Dietitian Credentialing, Dietetic Internship University of Alabama at Birmingham; Birmingham, AL Jessica A. Alvarez, PhD, RD Page 2 2005-2007 MS, Clinical Nutrition University of Alabama at Birmingham; Birmingham, AL Thesis title: The Association Between Insulin and Inflammation in African American and European American Children 2006-2011 PhD, Nutrition Sciences University of Alabama at Birmingham; Birmingham, AL Dissertation title: 25-Hydroxyvitamin D, Vascular Function, and Insulin Sensitivity 8. POSTGRADUATE TRAINING: 2011-present Postdoctoral Research Fellowship, Division of Endocrinology, Metabolism and Lipids, Department of Medicine, Emory University School of Medicine, Atlanta, GA; Supervisor: Vin Tangpricha, MD, PhD, Co-Supervisor: Thomas R. Ziegler, MD 2013-2014 Certificate Program in Translational Research, Atlanta Clinical & Translational Science Institute; Emory University; Atlanta, GA 2013-present Cystic Fibrosis Scholar’s Program, Emory+Children’s Center for CF and Airways Disease Research, Emory University, Atlanta, GA; Supervisors: Arlene A. Stecenko, MD, and Nael A. McCarty, PhD 9. COMMITTEE MEMBERSHIPS: 2008-2009 2008-2010 2010-2011 2010-2011 Dietetic Internship Advisory Board, University of Alabama at Birmingham; Birmingham, AL Co-Chair, New Member Recruitment committee, Alabama Dietetic Association Website Committee, Alabama Dietetic Association Nominating Committee, Birmingham District Dietetic Association 10. MANUSCRIPT REVIEWER: 2011-present 2013-present 2014-present International Journal of Endocrinology Clinical Nutrition Nutrition, Metabolism & Cardiovascular Diseases Canadian Journal of Diabetes BMC Endocrine Disorders International Journal of Obesity Journal of Pediatric Biochemistry American Journal of Clinical Nutrition Diabetes Care Advances in Nutrition Journal of Clinical Endocrinology and Metabolism Clinical Endocrinology Jessica A. Alvarez, PhD, RD Page 3 11. HONORS AND AWARDS: 2004 2005 2005 2005 2007 2007 2007 2008 2009 2009 2009 2009 2009 2009 2010 2011 2011 2011 2011 2012 2013 2013 2014 UAB Dietetic Internship Carol B. Craig Scholarship UAB Dietetic Internship E. Neige Todhunter Award Alabama Dietetic Association Memorial/Honor Scholarship Alabama Dietetic Association William E. Smith Scholarship Office of Dietary Supplements and National Institutes of Health Travel Award UAB Department of Nutrition Sciences Research Poster Award UAB School of Health Professionals Dean’s Diversity Scholarship UAB Center for Clinical and Translational Science TL1 Training Grant Fellowship Birmingham District Dietetic Association Recognized Young Dietitian of the Year American Dietetic Association, Alabama Memorial Scholarship The Endocrine Society Presidential Poster Award Minority Health & Health Disparities Research Center Charles Barkley Health Disparities Investigator Award, 2nd Place The Endocrine Society Outstanding Abstract Travel Grant Award Selection for Endocrine Trainee Day at the Annual Endocrine Society Meeting Alabama Dietetic Association Recognized Young Dietitian of the Year Science Unbound Foundation’s Best Paper Award by a UAB Student in Obesity-Related Research The Endocrine Society Presidential Poster Award The Endocrine Society Outstanding Abstract Travel Grant Award Howerde E. Sauberlich Endowed Award for Excellence in Nutrition Sciences Research Trainee Research and Travel Award, Southern Section-American Federation for Medical Research and the Southern Society for Clinical Investigation Trainee Research and Travel Award, Southern Section-American Federation for Medical Research and the Southern Society for Clinical Investigation Invited Presenter Award, Emory University Postdoctoral Association FASEB Minority Access to Research Careers Travel Award 12. SOCIETY MEMBERSHIPS: 2002-present 2004-2006 2004-2011 2004-2011 2005-present 2008-present 2010-present 2011-2012 2011-2013 2011-present American Dietetic Association (ADA)/Academy of Nutrition and Dietetics (AND) ADA Pediatric Nutrition Practice Group Alabama Dietetic Association Birmingham District Dietetic Association ADA/AND Research Nutrition Practice Group The Endocrine Society American Society for Nutrition American Heart Association American Federation For Medical Research Georgia Academy of Nutrition and Dietetics Jessica A. Alvarez, PhD, RD Page 4 13. RESEARCH FOCUS: My research focuses on the role of nutrition and body composition on metabolism in chronic diseases, including cystic fibrosis and cystic fibrosis-related diabetes, type 2 diabetes, cardiovascular disease, and chronic kidney disease. My research integrates state-of-the-art metabolomics with many aspects of nutrition research including rigorous clinical trials, body composition analysis, biomarker assessment, analysis of dietary intake and physical activity. Specific research foci include: 1) use of plasma high-resolution metabolomics, redox and bioenergetic assessment to identify targets for nutritional intervention to optimize health in adults with cystic fibrosis and cystic fibrosis-related diabetes, 2) role of vitamin D in sulfur/disulfide thiol redox, insulin sensitivity, vascular function, and clinical outcomes in the general population and various clinical diseases (e.g., cystic fibrosis and chronic kidney disease, 3) role of diet, body composition, and energy metabolism in ethnic health disparities of chronic diseases including type 2 diabetes mellitus and cardiovascular disease, and 4) role of diet in sulfur/disulfide thiol redox-mediated pathophysiology. 14. GRANT SUPPORT: a. Active Support: 1. P30 ES019776-01A1S1 (Miller) 03/15/2014-03/15/2015 NIH/NIEHS Annual Directs: $35,000 HERCULES: Health and Exposome Research Center at Emory Pilot Grant “The Human Airway Ecosystem: Metabolomics and Trace Element Profiling to Track Complex Exposures in Chronic and Acute Disease” (Pilot PI: Tirouvanziam) The goal of this pilot proposal is to establish a robust pipeline for high-resolution metabolomics and trace element profiling of human airway fluid to allow powerful explorations of the complex exposures that shape the human airway ecosystem. Role: Pilot Project Co-Investigator 2. K01 DK102851 (Alvarez) 08/01/2014-07/01/2019 NIH/NIDDK Annual Directs: $99,320 “Integration of Nutritional Metabolomics with Bioenergetics in Cystic Fibrosis” The primary goal of this career development proposal is for Dr. Alvarez to develop expertise in highresolution metabolomics analysis for use in clinically-oriented nutrition research. The aims of the research project are to integrate metabolomics with redox biology and bioenergetic assessment in adults with cystic fibrosis. Role: Principal Investigator b. Pending Support: 1. R23 (#pending) (Ziegler, Jones, Quyyumi) NHBLI “Dietary Regulation of Cystine/Glutathione Redox-Mediated Cardiovascular Disease Risk” The objective of this project is to test the overall hypotheses that plasma cysteine/glutathione redox status: 1) is determined by dietary sulfur amino acid intake; and 2) functionally impacts flow-mediated vasodilation and other pathogenic processes linked to CVD. Role: Co-Investigator 2. R01 (# pending) (Il’yasova) Jessica A. Alvarez, PhD, RD Page 5 NIH/NIDDK “Early Identification of Risk of Type 2 Diabetes and Obesity in African Americans” The objective of this study is to determine whether urinary isoprostane (F2-IsoP) levels are a biomarker of fat oxidation, mitochondrial function, and/or intramuscular adipose issue content in a cohort of active versus sedentary African Americans and Caucasians. Role: Co-Investigator c. Previous Support: 1. TL1 RR025775 (Guay-Woodford) 07/01/2008-06/31/2009 NIH/NCATS This training grant fellowship provided support for doctoral students to acquire competencies necessary to conduct clinical and translational research. Role: Predoctoral Trainee 2. Alabama Louis Stoke Alliance for Minority Participation (Dale) National Science Foundation This grant provided short-term stipend support. Role: Graduate Student 08/01/2008-12/31/2008 3. K12 HD043397 (Ashraf) 12/01/2008-11/30/2011 NIH/NICHD Child Health Research Center Development Award “Serum 25-Hydroxyvitamin D, Vascular Functioning, and Insulin Sensitivity in Adolescent Girls” The goal of this study was to investigate the relationships of serum 25(OH)D, vascular function, and insulin sensitivity in African American and European American adolescent girls. Role: Graduate Student Trainee 4. 09PRE2100038 (Alvarez) 07/01/2009-07/01/2011 American Heart Association Predoctoral Fellowship Greater Southeast Affiliate “25-Hydroxyvitamin D, Vascular Functioning, and Insulin Sensitivity in a Bi-Ethnic Population” The goal of this study was to investigate the interrelationships of vitamin D, vascular function, and insulin sensitivity in African American and European American populations. Role: Principal Investigator 5. P60 DK-079626 (Ashraf) 10/01/2009-11/30/2010 ARRA/NIDDK DRTC Pilot and Feasibility Program “Vitamin D, Vascular Function and Insulin Sensitivity in Adults” The goal of this study was to investigate the relationships of serum 25(OH)D, vascular function, and insulin sensitivity in African American, European American, and Hispanic American adults. Role: Graduate Student Trainee 6. TANGOR11A0 (Tangpricha) 07/01/2011-06/30/2014 Cystic Fibrosis Foundation Therapeutics Annual Directs: $217,531 “Vitamin D for Enhancing the Immune System in Cystic Fibrosis” The aims of this multicenter, double-blind randomized project are to examine the impact of high-dose vitamin D on clinical outcomes (infections, readmissions and survival) and antimicrobial peptide expression in adult and adolescent CF patients hospitalized for an acute pulmonary exacerbation. Role: Postdoctoral trainee Jessica A. Alvarez, PhD, RD Page 6 7. T32 DK007298-32S1 (Pacifici) 07/01/2011-06/30/2014 NIH/NIDDK Annual Directs: $57,690 “Endocrinology, Metabolism, and Diabetes” This award supports the training of MD and PhD underrepresented minority trainees as full-time academic scientists. My specific project is to investigate the effects of high-dose vitamin D in patients with early stage chronic kidney disease and in patients with CF. Role: Postdoctoral Trainee 15. FORMAL TEACHING: 2005-2006 2006-2011 2007 2009 Nutrition Instructor, Children’s Hospital of Alabama, Children’s Harbor Asthma Summer Camp; Birmingham, AL Moderator, Bionutrition Journal Club, General Clinical Research Center, University of Alabama at Birmingham Co-Instructor, Journal Club in Clinical Nutrition (NTR 680) Department of Nutrition Sciences, University of Alabama at Birmingham Teaching Assistant, Dental Nutrition (DENT 3337), Department of Nutrition Sciences and School of Dentistry, University of Alabama at Birmingham 16. SUPERVISORY TEACHING: a. PhD students directly supervised: (Date, Name, Current Position) 2013-present Ellen M. Smith, BS Third year PhD student, Nutrition and Health Sciences, Graduate Division of Biological and Biomedical Sciences, Emory University b. Post-doctoral fellows directly supervised: 2011-2013 Oranan Siwamogsatham, MD Pediatric Endocrinologist, Samitivej Srinakarin Hospital, Bangkok Hospital Group, Bangkok, Thailand 2013-present Jennifer L. Jones, PhD, RD Postdoctoral Research Fellow, Division of Endocrinology, Metabolism and Lipids, Department of Medicine, Emory University School of Medicine c. Other students directly supervised: 2005-2011 Research Rotation Student Preceptor for Dietetic Interns, General Clinical Research Center, University of Alabama at Birmingham; Birmingham, AL 2011 Breanne Wright, BS PhD Student, Nutrition Sciences, Purdue University 2012-2013 Aneesha Thobani, BS Second year medical student, Mercer University School of Medicine-Macon Jessica A. Alvarez, PhD, RD Page 7 2012-present Moon Lee, BS Clinical Research Coordinator, Division of Endocrinology, Metabolism and Lipids, Department of Medicine, Emory University School of Medicine 2013-present Ivana Stojkic Senior, Emory University 2013-2014 Daud Lodin, BS First Year Medical Student, San Juan Bautista School of Medicine, San Juan, Puerto Rico 17. LECTURESHIPS, SEMINAR INVITATIONS, AND VISITING PROFESSORSHIPS: 2005 Spinal Muscular Atrophy: A Nutritional Perspective, Invited Speaker, The Children’s Hospital of Alabama Pulmonary Division Seminar Series; Birmingham, AL 2007 Spinal Muscular Atrophy: A Nutritional Perspective, Invited Speaker, Birmingham Chapter of the Families of Spinal Muscular Atrophy Parent Group. Birmingham, AL 2007 Inflammation Overload: Associations of Inflammatory Markers with Insulin Resistance. Guest Lecturer, Advanced Medical Nutrition (NTR 601), Department of Nutrition Sciences, University of Alabama at Birmingham 2010 Vitamin D and Extra-Skeletal Health Outcomes in Pediatrics, Invited Speaker, Intensive Course in Nutrition for Infants, Children, and Adolescents (Annual Pediatric Conference); Birmingham, AL 2010 Vitamin D, Insulin Resistance and Cardiovascular Risk, Invited Presenter, 21st Annual University of Alabama at Birmingham Vascular Biology & Hypertension Symposium; Birmingham, AL 2010 Vitamin D Associations with Insulin Sensitivity, Guest Lecturer, Advanced Medical Nutrition (NTR 601), Department of Nutrition Sciences, University of Alabama at Birmingham 2011 Vitamin D Associations with Insulin Sensitivity and Vascular Function, Invited Speaker, Atlanta Vitamin D Research Seminar Series, Emory University 2012 Diet Quality and RDA Rationale, Guest Lecturer, Introduction to Nutrition (HLTH220), Emory University 2012 Vitamin D, Insulin Sensitivity, and Vascular Function, Invited Speaker, Department of Physiology and Biophysics Seminar Series, University of Mississippi Medical Center, Jackson, MS 2013 Effects of High-Dose Cholecalciferol in Patients with Early Chronic Kidney Disease: a Pilot, Randomized, Double-Blind, Placebo-Controlled Trial, Invited Speaker, Children’s Healthcare of Atlanta Nutrition Support Colloquium; Atlanta, GA Jessica A. Alvarez, PhD, RD Page 8 2014 JMP® Tutorial for Translational Science, Guest Lecturer, Biostatistics for Translational Science (CPTR 502), Emory University 2014 Conducting Systematic Reviews, Guest Lecturer, Emory University Dietetic Internship; Atlanta, GA 18. INVITATIONS TO NATIONAL OR INTERNATIONAL CONFERENCES 2015 Nutritional Metabolomics in Cystic Fibrosis, Invited Speaker, American Society for Parenteral and Enteral Nutrition/Nutrition Week, Long Beach, CA 19. BIBLIOGRAPHY a. Original Research Articles in Refereed Journals: 1. Alvarez JA, Bush NC, Hunter GR, Brock DW, Gower BA. Ethnicity and weight status affect the accuracy of proxy indices of insulin sensitivity. Obesity 2008;16:2739-44. 2. Alvarez JA, Higgins PB, Oster RA, Fernandez JR, Darnell BE, Gower BA. Fasting and postprandial markers of inflammation in lean and overweight children. American Journal of Clinical Nutrition 2009;89:1138-44. PMCID: PMC2667459 *Comment in American Journal of Clinical Nutrition 2009 Nov;90(5):1446; author reply, 1446-7 3. Ashraf A, Alvarez J, Saenz K, Gower B, McCormick K, Franklin F. Threshold for effects of vitamin D deficiency on glucose metabolism in obese female African American adolescents. Journal of Clinical Endocrinology & Metabolism 2009;94:3200-06. PMCID: PMC2819826 4. Chandler-Laney P, Hunter G, Bush N, Alvarez J, Roy J, Byrne N and Gower B. Associations among body size dissatisfaction, perceived dietary control, and diet history in African American and European American women. Eating Behaviors 2009;10:202-208. PMCID:PMC2752653 5. Brock DW, Chandler-Laney PC, Alvarez J, Gower B, Gaesser GA, and Hunter GR. Perception of exercise difficulty predicts weight regain in formerly overweight women. Obesity 2010;18:982-6. PMCID:PMC2924634 6. Gower BA, Hunter GR, Chandler-Laney P, Alvarez J, Bush N. Glucose metabolism and diet predict changes in adiposity and fat distribution in weight-reduced women. Obesity 2010; 18:1532-7. PMCID: PMC3070365 7. Bush NC, Alvarez JA, Choquette SS, Hunter GR, Oster RA, Darnell BE, Gower BA. Dietary calcium intake is associated with less gain in intra-abdominal adipose tissue over 1 yr. Obesity 2010;18:2101-4. PMCID: PMC2902577 8. Alvarez JA, Bush NC, Choquette SC, Hunter GR, Darnell BE, Oster RA, Gower BA. Vitamin D intake is associated with insulin sensitivity in African American, but not European American, women. Nutrition & Metabolism 2010, 7:28. PMCID: PMC2868016 Jessica A. Alvarez, PhD, RD Page 9 9. Hanks L, Casazza K, Alvarez JA, Fernandez J. Does Fat Fuel the Fire: Independent and interactive effects of genetic, physiological, and environmental Factors on Variations in Fat Deposition and Distribution across Populations. Journal of Pediatric Endocrinology & Metabolism 2010;23:1233-34. PMCID: PMC3208239 10. Alvarez JA, Ashraf A, Hunter G, Gower B. Serum 25-Hydroxyvitamin D and Parathyroid Hormone are Independent Determinants of Whole-Body Insulin Sensitivity. American Journal of Clinical Nutrition 2010;92:1344-9. PMCID: PMC2980959 *Comment in American Journal of Clinical Nutrition 2011;93(3):672-3; author reply 673-4 * Science Unbound Foundation’s Best Paper Award by a UAB student in obesity-related research, 2011 11. Chandler-Laney PC, Brock DW, Gower BA, Alvarez JA, Bush NC, Hunter GR. Self-reported low vitality, poor mental health, and low dietary restraint are associated with over-perception of physical exertion. Journal of Obesity 2010; vol 2010: Article ID 207451. PMCID: PMC2948900 12. Bush NC, Alvarez JA, Hunter GR, Brock DW, Chandler-Laney PC, Gower BA. Ethnicity-specific anthropometric predictors of metabolic risk in women. International Journal of Body Composition Research 2010;8:69-79. PMCID: PMC3172136 13. Ashraf A, Alvarez JA, Gower BG, Saenz K, McCormick K. Associations of serum 25-hydroxyvitamin D and components of the metabolic syndrome in obese adolescent females. Obesity 2011;19:2214-21. PMCID: PMCIn Process 14. Ellis AC, Alvarez JA, Granger WM, Dalla Man C, Cobelli C, Ovalle F, Gower BA. Ethnic differences in glucose disposal, hepatic insulin sensitivity, and endogenous glucose production among African American and European American women. Metabolism 2012;61:634-40. PMCID: PMC3288425 15. Fisher G, Alvarez JA, Ellis AC, Granger WM, Ovalle F, Dalla Man C, Cobelli C, Gower BA. Race differences in the associations of oxidative stress and insulin sensitivity. Obesity 2012;20:972-7. PMCID: PMC3687548 16. Alvarez JA, Gower BA, Calhoun DA, Judd SE, Dong Y, Dudenbostel T, Scholl J, Ashraf AP. Serum 25hydroxyvitamin D and ethnic differences in arterial stiffness and endothelial function. Journal of Clinical Medicine Research 2012;197-205. PMCID: PMC3376878 17. Alvarez JA, Law J, Coakley KE, Zughaier SM, Hao L, Salles KS, Wasse H, Guitiérrez OM, Ziegler TR, Tangpricha V. High-dose cholecalciferol reduces parathyroid hormone in patients with early chronic kidney disease: a pilot, randomized, double-blind, placebo-controlled trial. American Journal of Clinical Nutrition 2012;96:672-9. PMCID: PMC3417221 18. Osunkwo I, Ziegler TR, Alvarez J, McCracken C, Cherry K, Osunkwo C, Ofori-Acquah S, Ghosh S, Ogunbobode A, Rhodes J, Eckman J, Dampier C, Tangpricha V. High dose vitamin D therapy decreases chronic pain and improves quality of life in children and adolescents with sickle cell disease. British Journal of Haematology 2012;159:211-5. PMCID: PMC3460143 Jessica A. Alvarez, PhD, RD Page 10 19. Ashraf AP, Fisher G, Alvarez J, Dudenbostel T, Calhoun DA, Szalai AJ, Gower BA. Associations of Creactive protein to indices of vascular health and the influence of serum 25(OH)D status in healthy adults. Journal of Nutrition & Metabolism 2012; vol 2012: Article ID 475975. PMCID: PMC3457628 20. Hanks LJ, Casazza K, Ashraf AP, Beasley M, Alvarez JA, Fernandez JR. BMI, but not race contributes to vitamin D-parathyroid hormone axis in peripubertal girls. ICAN: Infant, Child, & Adolescent Nutrition 2012. doi:10.1177/1941406412472699. Available at: http://can.sagepub.com/content/5/2/100.abstract?rss=1 21. Gower BA, Alvarez JA, Bush NC, Hunter GR. Insulin sensitivity affects propensity to obesity AfricanAmerican in an ethnic-specific manner: results from two controlled weight loss intervention studies. Nutrition & Metabolism 2013;10:3. doi:10.1186/1743-7075-10-3. PMCID: PMC3571978 22. Alvarez JA, Zughaier SM, Law J, Hao L, Wasse H, Ziegler TR, Tangpricha V. Effects of high-dose cholecalciferol on serum markers of inflammation and immunity in patients with early chronic kidney disease. European Journal of Clinical Nutrition 2013;67:264-9. PMCID: PMC3824962. 23. Ashraf AP, Alvarez J, Huisingh C, Casazza K, Gower B. Higher serum insulin concentrations positively influence the bone mineral density in African American adolescents. British Journal of Medicine & Medical Research 2013;3:1050-1061. PMC-In Process 24. Middleton JP, Bhagavathula AP, Gaye B, Alvarez JA, Huang CS, Sauer CG, Tenjarla G, Schoen BT, Kumar A, Prasad M, Okou DT, Ifeadike WC, Dhere TA, Conneely KN, Ziegler TR, Tangpricha V, Kugathasan S. Vitamin D Status And Bone Mineral Density In African American Children With Crohn's Disease. Journal of Pediatric Gastroenterology and Nutrition 2013;57:587-93. PMCID: PMC3845217. 25. Hanks LJ, Ashraf AP, Gower BA, Alvarez JA, Casazza K. Subclinical indication of linkage between markers of skeletal and cardiovascular properties. Bone Research 2013;3: 291-297. NIHMSID: NIHMS590766 26. Ashraf AP, Huisingh C, Alvarez JA, Wang X, Gower BG. Insulin resistance indices are inversely associated with vitamin D binding protein concentrations. Journal of Clinical Endocrinology and Metabolism 2014;99:178-183. PMCID:PMC3879668 27. Chandler-Laney PC, Higgins PB, Granger W, Alvarez J, Casazza K, Fernandez JR, Dalla Man C, Cobelli C, Gower BA. Use of a simple liquid meal test to evaluate insulin sensitivity and beta-cell function in children. Pediatric Obesity 2014;9:102-10. PMCID: PMC-In Process 28. Ellis AC, Alvarez JA, Gower BA, Hunter GR. Cardiorespiratory fitness in older adult women: relationships with serum 25-hydroxyvitamin D. Endocrine 2014, Feb 22 [Epub ahead of print]. PMCID: PMC-In Process. 29. Zughaier SM, Alvarez JA, Sloan JH, Konrad RJ, Tangpricha V. The Role of vitamin D in regulating the iron-hepcidin-ferroportin axis in monocytes. Journal of Clinical and Translational Endocrinology 2014. Available at http://dx.doi.org/10.1016/j.jcte.2014.01.003. PMCID: PMC-In Process 30. Siwamogsatham O, Dong W, Binongo JN, Chowdhury R, Alvarez JA, Feinman SJ, Enders J, Tangpricha V. Relationship between fat-soluble vitamin supplementation and blood concentrations in adolescent and adult patients with cystic fibrosis. Nutrition in Clinical Practice 2014, April 17 [Epub ahead of print]. PMCID: PMC-In Process Jessica A. Alvarez, PhD, RD Page 11 31. Alvarez JA, Chowdhury R, Jones DP, Martin GS, Brigham KL, Binongo JN, Ziegler TR, Tangpricha V. Vitamin D status is independently associated with plasma glutathione and cysteine thiol/disulfide redox status in adults. Clinical Endocrinology 2014, Mar 13 [Epub ahead of print]. NIHMSID: NIHMS574031 32. Tangpricha V, Judd SE, Ziegler T, Hao L, Alvarez JA, Fitzpatrick AM, McComsey G, Eckard AR. LL-37 concentrations and the relationship to vitamin D, immune status, and inflammation in HIV-infected children and young Adults. AIDS Research and Human Retroviruses 2014, May 5 [Epub ahead of print]. PMCID: PMC-In process b. Manuscripts submitted: 1. Smith EM, Alvarez JA, Martin GS, Zughaier SM, Ziegler TR, Tangpricha V. Vitamin D deficiency is associated with anemia: a cross-sectional study in healthy adults in the United States. Eur J Clin Nutr 2014. Under review. 2. Alvarez JA, Ziegler TR, Millson EC, Stecenko AA. The paradox of normal weight obesity in cystic fibrosis. JAMA 2014. Under review. 3. Kempker JA, West KG, Kempker RR, Siwamogsatham O, Alvarez JA, Tangpricha V, Ziegler TR, Martin GS. Vitamin D and the risk for hospital-acquired infections in critically ill adults: a prospective cohort. PLOS One 2014. Under review. c. Review Articles: 1. Alvarez JA, Ashraf A. Role of vitamin D in insulin secretion and insulin sensitivity for glucose homeostasis. International Journal of Endocrinology 2010;2010:351385. PMCID: PMC2778451 2. Alvarez JA, Wasse H, Tangpricha V. Vitamin D supplementation in pre-dialysis chronic kidney disease: A systematic review. Dermato-Endocrinology 2012;4:118-27. PMCID: PMC3427190 3. Kearns MD, Alvarez JA, Tangpricha V. Large, single-dose oral vitamin D supplementation in adult populations: a systematic review. Endocrine Practice 2014;20:341-51. PMCID: PMC-in process 4. Siwamogsatham O, Alvarez JA, Tangpricha V. Diagnosis and treatment of endocrine comorbidities in patients with cystic fibrosis. Curr Opin Endocrinol Diabetes Obes 2014. In press. d. Book Chapters: 1. Casazza K, Hanks LJ, Alvarez J. The role of various cytokines and growth factors in pubertal development. In: Physical Activity, Cytokines and Growth Mediators in Childhood and Adolescence. J. and T. Jürimäe (Tartu), AP. Hills (Brisbane) eds. Karger, 2010, 14-31. e. Abstracts: 1. Alvarez J, McLeod K, and Smith A. The consumption of soy and breast cancer rates among Asian women vs. Asian-American women: A Review. Poster. Annual Alabama Dietetic Association Meeting, Mobile, AL, March 2005. Jessica A. Alvarez, PhD, RD Page 12 2. Alvarez J, Harris C, King J, Lanfair K, and Torsch S. Health insurance disparities of Latino children in the United States: a data and literature review. Poster. UAB Maternal and Child Health Network Seminar: Emerging Issues in Health Care: Latino Populations, The Children’s Hospital of Alabama, Birmingham, AL, March 2006. 3. Bush N, Alvarez J, Brock D, Hunter G, Gower B. Thigh circumference is independently associated with greater insulin sensitivity and lower cardiovascular risk in healthy Black and White premenopausal women. Poster. UAB Department of Nutrition Sciences Annual Retreat, Birmingham, AL, August 2007. 4. Alvarez J, Bush N, Brock D, Hunter G, Gower B. Accuracy of proxy indices of insulin sensitivity is affected by ethnicity and obesity. Poster. UAB Department of Nutrition Sciences Annual Retreat, Birmingham, AL, August 2007. *UAB Department of Nutrition Sciences Research Poster Award 5. Bush N, Alvarez J, Brock D, Hunter G, Gower B. Thigh circumference is independently associated with greater insulin sensitivity and lower cardiovascular risk in healthy Black and White premenopausal women. Poster. Annual Obesity Society Conference, New Orleans, LA, October 2007. (Published in Obesity 2007;15:A72.) 6. Alvarez J, Bush N, Brock D, Hunter G, Gower B. Accuracy of proxy indices of insulin sensitivity is affected by ethnicity and obesity. Poster. Annual Obesity Society Conference, New Orleans, LA, October 2007. (Published in Obesity 2007;15:A65) 7. Alvarez J, Higgins P, Oster S, Fernandez J, Darnell B, Gower B. Fasting and postprandial insulin are not associated with inflammation in African American and European American children. Poster. Annual Obesity Society Conference, New Orleans, LA, October 2007. (Published in Obesity 2007;15:A82) 8. Chandler-Laney P, Alvarez J, Brock D, Gower B, Bush N, Hunter G. Low dietary restraint and low vitality are associated with over-estimation of physical exertion. Poster. Annual Obesity Society Conference. Phoenix, AZ, October 2008. (Published in Obesity 2008;16:S276) 9. Chandler-Laney P, Bush N, Hunter G, Alvarez J, Gower B. Weight gain differentially affects self-reported body dissatisfaction and dietary control of African American and European American women. Poster. Annual Obesity Society Conference. Phoenix, AZ, October 2008. (Published in Obesity 2008;16: S214) 10. Alvarez J, Bush N, Goss M, Choquette S, Hunter G, Gower B. Ethnic-specific associations of dietary vitamin D and calcium with insulin sensitivity. Oral presentation. UAB Graduate Student Research Days, Birmingham, AL, February 2009. 11. Alvarez J, Bush N, Goss M, Choquette S, Hunter G, Gower B. Associations of dietary vitamin D and calcium with insulin sensitivity. Oral presentation. UAB Health Disparities Research Symposium, Birmingham, AL, April 2009. *Minority Health & Health Disparities Research Center Charles Barkley Health Disparities Investigator Award, 2nd Place 12. Alvarez JA, Bush NC, Goss AM, Choquette SS, Hunter GR, Gower BA. Dietary vitamin D and calcium are differentially associated with insulin sensitivity among African American and European American premenopausal women. Poster. The Endocrine Society Annual Meeting, Washington DC, June 2009. Jessica A. Alvarez, PhD, RD Page 13 *The Endocrine Society Presidential Poster Award and Outstanding Abstract Travel Award 13. Bush NC, Alvarez JA, Goss AM, Hunter GR, Gower BA. Adiponectin independently predicts change in insulin sensitivity over 1 yr and has ethnic-specific associations with leg fat. Poster. The Endocrine Society Annual Meeting, Washington DC, June 2009. 14. Ashraf A, Alvarez J, Saenez K, Gower B, McCormick K, Franklin F. Does a different threshold for vitamin D exist for effects on glucose metabolism in obese African American adolescents? Poster. The Endocrine Society Annual Meeting, Washington DC, June 2009. 15. Ellis AC, Alvarez JA, Granger WM, Dalla Man C, Cobelli C, Fernandez JR, Ovalle F, Gower BA. Associations between adiposity and insulin-mediated glucose disposal in African American and European American females. Poster. Endocrine Society Annual Meeting, San Diego, CA, June 2010. (Published in Endocrine Reviews 2010;31:S2226) 16. Ashraf AP, Alvarez JA, Saenz K, Gower BA, McCormick K. Vitamin D affects components of metabolic syndrome in obese adolescent females. Poster Presentation. Endocrine Society Annual Meeting, San Diego, CA, June 2010. (Published in Endocrine Reviews 2010;31:S2433) 17. Alvarez JA, Ashraf AP, Hunter GR, Gower BA. Serum 25-hydroxyvitamin D is an independent determinant of whole-body insulin sensitivity. Poster Presentation. Endocrine Society Annual Meeting, San Diego, CA, June 2010. (Published in Endocrine Reviews 2010;31:S226) 18. Hanks L, Casazza K, Alvarez J, Fernandez J. Does fat fuel the fire: investigating the inter-relationships between adipose tissue, bone, and markers of inflammation. The Obesity Society Annual Meeting, San Diego, CA, October 2010. (Published in Obesity 2010;18:S46) 19. Alvarez JA, Gower BA, Calhoun DA, Judd SE, Dong Y, Dudenbostel T, Ashraf AP. Associations between serum 25-hydroxyvitamin D and clinical indicators of vascular function among apparently healthy African American and European American adults. Oral presentation. University of Alabama at Birmingham Graduate Student Research Days, Birmingham, AL, February 2010. 20. Ellis AC, Alvarez JA, Granger WM, Dalla Man C, Cobelli C, Ovalle F, Gower BA. Ethnic differences in insulin-stimulated glucose disposal, hepatic insulin sensitivity, and endogenous glucose production among African American and European American females. Poster. Endocrine Society Annual Meeting, Boston, MA, June 2011. 21. Ashraf AP, Alvarez JA, Granger WM, Gower BA. Associations between serum 25(OH)D and indices of hepatic and whole-body insulin sensitivity: effects of fasting glucose status. Poster Presentation. Endocrine Society Annual Meeting, Boston, MA, June 2011. 22. Alvarez JA, Gower BA, Calhoun DA, Judd SE, Dong Y, Dudenbostel T, Ashraf AP. Associations between 25(OH)D and clinical indicators of vascular function among apparently healthy African American and European American adults: relationships may differ with ethnicity. Poster Presentation. Endocrine Society Annual Meeting, Boston, MA, June 2011. *The Endocrine Society Presidential Poster Award and Outstanding Abstract Travel Award Jessica A. Alvarez, PhD, RD Page 14 25. Alvarez JA, Law J, Coakley K, Hao L, Ziegler TR, Tangpricha V. High-dose vitamin D supplementation in patients with early stage chronic kidney disease: a randomized, placebo-controlled trial to increase circulating 25-hydroxyvitamin D and prevent secondary hyperparathyroidism. Oral presentation. Southern Regional Annual Meeting of the American Federation for Medical Research, New Orleans, LA, February 2012. (Published in Journal of Investigative Medicine 2012;60:433)** * Trainee Research and Travel Award from the Southern Section-American Federation for Medical Research and the Southern Society for Clinical Investigation 26. Alvarez JA, Law J, Coakley K, Wright B, Hao Li, Ziegler T, Tangpricha V. A prospective, randomized, placebo-controlled trial of high-dose vitamin D for prevention of vitamin D insufficiency in early stage chronic kidney disease. Oral presentation. Experimental Biology/American Society for Nutrition Annual Meeting, San Diego, CA, April 2012. (Published in The FASEB Journal 2012;26:41.5) 27. Wright B, Coakley K, Alvarez JA, Tangpricha V. Baseline vitamin D status in patients with chronic kidney disease. Poster presentation. Experimental Biology/American Society for Nutrition Annual Meeting, San Diego, CA, April 2012. (Published in The FASEB Journal 2012;26:626.7) 28. Siwamogsatham O, Alvarez JA, Enders JL, Tangpricha V. Trends in fat-soluble vitamin intakes and blood concentrations in adults subjects with cystic fibrosis. Poster. Annual North American Cystic Fibrosis Conference, Orlando, FL, October 2012. (Published in Pediatric Pulmonology 2012;47:413) 29. Alvarez JA, Zughaier SM, Law J, Hao L, Wasse H, Ziegler TR, Tangpricha V. Effects of high-dose cholecalciferol on serum markers of inflammation and immunity in patients with early chronic kidney disease. Oral presentation. Southern Regional Annual Meeting of the American Federation for Medical Research, New Orleans, LA, February 2013. (Abstract published in Journal of Investigative Medicine 2013;61:509) * Trainee Research and Travel Award from the Southern Section-American Federation for Medical Research and the Southern Society for Clinical Investigation 30. Siwamogsatham O, Alvarez J, Tangpricha V. Trends in fat-soluble vitamin intakes and blood concentrations in adults subjects with cystic fibrosis. Oral presentation. Southern Regional Annual Meeting of the American Federation for Medical Research, New Orleans, LA, February 2013. (Published in Journal of Investigative Medicine 2013;61:509) 31. Alvarez JA, Zughaier SM, Law J, Hao L, Wasse H, Ziegler TR, Tangpricha V. Effects of high-dose cholecalciferol on serum markers of inflammation and immunity in patients with early chronic kidney disease. Oral presentation. Experimental Biology/American Society for Nutrition Annual Meeting, Boston, MA, April 2013. (Published in The FASEB Journal 2013;27:46.3) 32. Alvarez JA, Stecenko A. Body composition and normal weight obesity in cystic fibrosis. Oral presentation. North American Cystic Fibrosis Conference, Salt Lake City, UT, October 2013. (Published in Pediatric Pulmonology 2013; Supplement 36:402.) 33. Alvarez JA, Mazer LM, Hebbar G, Frediani JK, Benton SM, Grossmann RE, Combs GF, Tangpricha Vin, Ziegler TR. Micronutrient status during acute pulmonary exacerbation in adult cystic fibrosis. Poster. North American Cystic Fibrosis Conference, Salt Lake City, UT, October 2013. (Published in Pediatric Pulmonology 2013; Supplement 36:403.) Jessica A. Alvarez, PhD, RD Page 15 34. Thobani A, Alvarez J, Blair SD, Gottlieb E, Jackson K, Tangpricha V. Life Space score and vitamin D status are associated with mobility in the adult CF population. Poster. North American Cystic Fibrosis Conference, Salt Lake City, UT, October 2013. (Published in Pediatric Pulmonology 2013; Supplement 36:364.) 35. Alvarez JA, Chowdhury R, Jones DP, Martin GS, Brigham KL, Binongo JN, Ziegler TR, Tangpricha V. Vitamin D status is linked with plasma glutathione and cysteine thiol/disulfide redox status in adults. Oral presentation. Experimental Biology/American Society for Nutrition Annual Meeting, San Diego, CA, April 2013. (Published in The FASEB Journal 2014;28:260.4) 36. Smith EM, Alvarez JA, Martin G, Zughaier S, Ziegler TR, Tangpricha V. Vitamin D deficiency is associated with anemia: a cross-sectional study in healthy adults in the United States. Oral presentation. Experimental Biology/American Society for Nutrition Annual Meeting, San Diego, CA, April 2013. (Published in The FASEB Journal 2014;28:260.3) 37. Alvarez, JA, Frediani JK, Jones DP, Grossmann RE, Uppal K, Tangpricha V, Ziegler TR. Plasma metabolomic profiling in adults with cystic fibrosis and cystic fibrosis-related diabetes. Oral Presentation. Experimental Biology/American Society for Nutrition Annual Meeting. San Diego, CA, April 2013. (Published in The FASEB Journal 2014;28:248.1)