Applications are invited for the following ERC Starting Grant funded research position: Postdoctoral Research Fellowship in Diffusion Tensor Imaging of Arterial Tissue (3 year contract) The aim of the project is to translate an existing diffusion tensor imaging protocol, used for fibre characterisation within animal arterial tissue, to one suitable for the characterisation of the arterial structure of healthy human carotid arteries. The research will also further develop an existing finite element based fibre remodelling algorithm for use in the prediction of fibre patterns in diseased human carotid arteries. The researcher will work closely with other members of a multidisciplinary team including PIs, clinicians, postdoctoral research fellows and postgraduate researchers in the Trinity Centre for Bioengineering, the Trinity College Institute of Neuroscience, and St. James’s Hospital Dublin. Candidates should have a PhD in biomedical imaging, bioengineering, computer science or a related discipline with specific expertise in medical imaging, preferably diffusion tensor imaging, soft tissue testing or tissue modelling experience and computer programming (e.g. Matlab). To apply for this position, submit a CV with the names and addresses of two referees to tcbe@tcd.ie with the subject heading ‘DTI Postdoctoral Research Fellow’ by July 15th, or to: Dr. Caitríona Lally, PhD Professor in Bioengineering, Trinty Centre for Bioengineering, Trinity College Dublin, Dublin 2, Ireland. Email: CLallytcd@gmail.com Applications are invited for the following ERC Starting Grant funded research position: Postdoctoral Research Fellowship in Vascular Tissue Engineering (3-year contract) This research aims to determine if the mechanical stimuli conferred by the natural collagen fibre network of a scaffold, derived from decellularised arterial tissue, can be tuned to induce stem cell differentiation and growth to develop a tissue engineered blood vessel. The postdoctoral researcher will characterise healthy and decellularised porcine coronary tissue using histological and imaging techniques and conduct a range of experiments to identify the influence of this strain and structure on the growth and differentiation of vascular smooth muscle cells and mesenchymal stem cells. The researcher will work closely with other members of a multidisciplinary project team including PIs, postdoctoral research fellows and postgraduate researchers in the Trinity Centre for Bioengineering and the School of Biotechnology in Dublin City University. Candidates should have a PhD in tissue engineering/bioengineering or related disciplines with specific experience in vascular tissue engineering. To apply for this position, submit a CV with the names and addresses of two referees to tcbe@tcd.ie with the subject heading ‘TE Postdoctoral Research Fellow’ by July 15th, or to: Dr. Caitríona Lally, PhD Professor in Bioengineering, Trinty Centre for Bioengineering, Trinity College Dublin, Dublin 2, Ireland. Email: CLallytcd@gmail.com Applications are invited for the following ERC Starting Grant funded research position: PhD Position in Arterial Biomechanics and MRI Imaging The aim of the research project is to develop a means of identifying alterations in collagen fibre architecture of arteries in vivo using non-invasive imaging techniques that can be linked with disease progression. DT-MRI has been used to characterise fibre patterns in animal tissue and this project will explore the means by which this can be enhanced in human tissue. Potential applications of the NODDI (neurite orientation dispersion and density imaging) protocol in arterial tissue will be explored. The researcher will work closely with other members of a multidisciplinary team including PIs, clinicians, postdoctoral research fellows and postgraduate researchers in the Trinity Centre for Bioengineering, the Trinity College Institute of Neuroscience, and St. James’s Hospital Dublin. Candidates should have a degree in biomedical imaging, bioengineering, computer science, electronic engineering or a related discipline with specific expertise in medical imaging, computer programming (e.g. Matlab) and/or arterial tissue characterisation. To apply for this position, submit a CV with the names and addresses of two referees to tcbe@tcd.ie with the subject heading ‘Vascular Imaging PhD’ by July 15th, or to: Dr. Caitríona Lally, PhD Professor in Bioengineering, Trinty Centre for Bioengineering, Trinity College Dublin, Dublin 2, Ireland. Email: CLallytcd@gmail.com