Heterotopic Ossification After Burn Injuries
Study
Main
Research
Sample
Purpose
Design
Crawford,
1986121
To determine
Incidence of
Heterotopic
Ossification
(HO).
Djurickovic To report
, 1996122
incidence of HO
and results of
surgical
excision.
Outcome
Measures
Results
Study
Level of
Category Evidence
Retrospective
review of patients
admitted to burn
center.
1,066
Radiological
consecutive
confirmation of
admissions to
HO.
burn center.
Patients who
developed
decreased ROM
and joint pain
had x-ray.
12 patients or 1.2% had
evidence of HO on X-ray.
Average TBSA 49% and 6
required surgical excision.
Prognostic
III
Retrospective
review of
admissions to burn
unit between 1982
through 1993.
1,855
consecutive
admissions to
burn center.
24 patients with diagnosis of HO Prognostic
or 1.2%. Elbow HO was present
in 18 of the 24 cases. 15
required surgical excision.
III
Radiological
confirmation of
HO.
Elledge,
1988123
To determine
Retrospective
Incidence of HO. review of burn
injury admissions
to U.S. Army
Institute of
Surgical Research
between 1967 and
1985.
5,031
Radiological
admissions to
confirmation of HO
burn center and
review of X-rays
completed
during routine
clinical care.
HO diagnosed in 63 patients for Prognostic
incidence of 1.2%. Average
TBSA was 44.6% and HO was at
the elbow in 82.5% of the cases.
Patients with HO had a longer
length of hospitalization
compared to those without HO.
III
Gaur,
2003125
To report on
Prospective, case
outcome of
series.
surgical excision
of HO.
8 children (10
elbows) with
severe HO after
burn injuries who
underwent
surgical
excision.
Average gain in ROM of 57
degrees. Follow-up completed
on 7 children (9 elbows).
IV
Range of motion
(ROM) before
surgery and at
follow-up 3 to 10
years later.
Therapeutic
Holguin,
1996126
To report on
outcome of
surgical excision
of HO.
Retrospective
study of patients
who required
surgical excision
for HO. No control
group.
6 subjects with
HO out of 2280
total patients. All
6 required
surgical
excision.
Range of motion
before surgery and
at follow-up 6
months to 22
years later.
Very good outcome in 5 subjects Therapeutic
with average gain in ROM of
73.6 degrees. One subject was
not cooperative with
postoperative treatment and had
poor outcome.
IV
Peterson,
1989124
To determine
Retrospective
1,478 individuals
Incidence of HO. review of
admitted to burn
consecutive
center.
admissions to burn
center.
All patients had
decreased ROM,
joint pain and x-ray
confirmation of
HO.
18 patients developed HO
Prognostic
(1.2%). 17 of the patients had
HO at the elbow. 10 patients
were treated conservatively and
8 with surgical excision. Both
groups had a large gain in ROM.
III
Tsionos,
2004127
To report on
Retrospective,
outcome of
case series.
surgical excision
of HO.
Range of motion
pre-op and at a
follow-up. Mean
follow-up was 21
months post-op.
Significant gain in ROM. 4
elbows had recurrence of the
HO.
III
28 patients (35
elbows) who had
surgical excision
of HO at the
elbow. Post-op
treatment with
splinting, CPM
and
indomethacn.
Therapeutic