International Cardiovascular Infection Symposium
2012 Final Programme
Monday 26 March
International cardiovascular infection symposium – Monday 26 March
Session 1: Scientific evidence and history
Chair
Howard Jenkinson (University of Bristol)
Dental infections and cardiovascular disease (CVD) – the early findings
09:00
Kimi Mattila (Helsinki University Hospital, Finland)
Epidemiological evidence of bacteria playing a role in the cardiovascular system
09.30
Lise Lund Håheim (University of Oslo, Norway)
Offered paper Impact of sub-inhibitory antibiotic concentrations on the plasminogen binding
10.00
ability on viridans group streptococci
Susan Lang (Glasgow Caledonian University)
10.15
Refreshments and Exhibition
Session 2: Models of disease
Chair
Steve Kerrigan (Royal College of Surgeons in Ireland, Ireland)
Imaging of platelets in real time in vivo
10.45
Neena Kalia (University of Birmingham)
Animal models of disease / infective endocarditis
11.15
Paul Sullam (University of California, San Francisco, USA)
Offered paper Platelet receptor polymorphisms do not influence Staphylococcus aureus11.45
platelet interactions or infective endocarditis
Shruti Daga (University of Edinburgh)
SGM Prize Medal Lecture
12.10
Molecules, Microbes and Me
Julian Davies (University of British Columbia, Canada)
13.00
Lunch and exhibition
Session 3: Infection in the cardiovascular system – Streptococci
Chair
Philippe Moreillon (University of Lausanne, Switzerland)
Streptococcal surface lipoproteins and endocarditis virulence
14.00
Todd Kitten (Virginia Commonwealth University, USA)
Offered paper Viridans bacterium Streptococcus gordonii mimics the actions of fibrinogen by
14.30
expression of aIIbß3 binding motifs
Helen Petersen (UCL Eastman Dental Institute & RCSI, Dublin, Ireland)
Offered paper A critical role for platelet FcγRIIa in Streptococcus oralis induced platelet
14:45
activation
Dorothea Tilley (The Royal College of Surgeons, Ireland)
Offered paper The facultative pathogen Streptococcus pneumoniae induces exocytosis
15.00
mechanisms of human lung endothelium
Simone Bergmann (Technische Universität Braunschweig, Germany)
15.15
Refreshments and Exhibition
Session 4: Infection in the cardiovascular system – Staphylococci
Chair
Oonagh Shannon (Lund University , Sweden)
Surface proteins of Staphylococcus aureus
15.45
Timothy Foster (Trinity College Dublin, Ireland)
Using a dynamic shear based system to investigate the interactions between S. aureus and
16.15
platelets
Steve Kerrigan (Royal College of Surgeons in Ireland)
Offered paper Iron regulated surface determinant B (IsdB) of S. aureus directly interacts with
16.45
integrins promoting adhesion and invasion of mammalian cells
Marta Anna Zapotoczna (Trinity College Dublin, Ireland)
17.00
Session ends
Tuesday 27 March
Infection & the cardiovascular system – Tuesday 27 March
Session 5: Infection in the cardiovascular system – Other micro-organisms
Chair
Kimi Mattila (Helsinki University Hospital, Finland)
Platelet activation mediated by Enterococcus faecalis and Aerococcus urinae
09.00
Oonagh Shannon (Lund University , Sweden)
Offered paper Staphylococcus lugdunensis, an unusual staphylococcus
09:30
Simon Heilbronner (Trinity College Dublin, Ireland)
Offered paper SNP genotyping of chromosomally integrated Human Herpesvirus 6 in patients
09:45
with acquired cardiomyopathies and heart failure symptoms
Dirk Lassner (Institute Cardiac Diagnostics and Therapy GmbH, Germany)
Offered paper CD36 is a Platelet Receptor for Bacterial Pathogens
10.00
Jennifer Mitchell (University College Dublin, Ireland)
10.15
Refreshments and Exhibition
Session 6: Current treatments & novel drug targets
Chair
Paul Sullam (University of California, San Francisco, USA)
Current treatment and management for Infective Endocarditis
10.45
Philippe Moreillon (University of Lausanne, Switzerland)
Novel Drug Targets for the treatment of Infective Endocarditis and bloodstream infection
11.15
Dermot Cox (Royal College of Surgeons in Ireland)
Offered paper Does Positron Emission Tomography have a role to play in the diagnosis of
11.45
infective endocarditis and its associated complications?
B. Cherie Millar (Belfast City Hospital, Belfast)
Marjory Stephenson Prize Lecture
12.10
Old themes and new variations in human tumor virology
Yuan Chang & Patrick Moore (University of Pittsburgh Cancer Institute)
13.00
Lunch and exhibition
Workshop: Open presentations
Chair
Angela Nobbs (University of Bristol, UK)
Offered paper Staphylococcus aureus lipoteichoic acid raises platelet cAMP levels via
14.00
interactions with the Paf receptor, inhibiting their activation
Amie Waller (University of Reading)
Offered paper FcγRIIA phosphorylation as a common mechanism of bacterial-mediated
14.15
platelet activation
Monica Arman (University of Birmingham)
Offered paper The role of platelet-neutrophil complexes in inflammation & infection
14.30
Sinéad Hurley (Lund University, Sweden)
Offered paper Von Willebrand factor fibers mediate luminal S. aureus adhesion to intact
14.45
endothelial cell layer under shear stress
Karin Pappelbaum (Medical Faculty Mannheim, Dermatology, Germany)
Offered paper Staphylococcus aureus lipoteichoic acid interacts with the human membrane
15.00
receptor CD36 on the surface of platelets
Alyson Murray (University College Dublin, Ireland)
Offered paper The role of Staphylococcus aureus wall teichoic acid in potentiating activation
15.15
of human platelets
Simon Clarke (University of Reading)
15.30
Refreshments and Exhibition
Framework Presentation & General Discussion
Chair
Dermot Cox (Royal College of Surgeons in Ireland)
16.00
Presentation from FP call
16.30
Group Discussion: Possibility of European Network or Consortium FP7 or FP8.
17.30
Session ends
Updated 29/02/2012