Swine Coccidiosis Members:Chen Hongxiu Cui Keqi Li Xiuying Luo Chuan Wang Ruijiao From:Class 1 2007 Introduction of swine coccidiosis • Coccidians parasite at intestinal epithelial cell ,and cause pig intestinal mucosa (粘 膜)bleeding and diarrhea Total introduction • Definitive host: pig • Site of infection: intestinal epithelial cell • Intective stage: sporulated oocyst • Diagnosis stage:oocyst Morphology • swine coccidiosis origins from many types ; • the classifies belongs to the Sporozoa, Eucoccidia, Eimeriina,Eimeria and Isospora of Eimeriidae of spores and genera. • Generally considered pathogenic strongly are Isospora suis、Eimeria debliecki E.scabra、E.spinosa . Oocysts of swine coccidians Eimeria One oocyst of Eimeria contain 4 sporoblasts oocysts of Isospora suis A Unsporulated Oocyst C Sporulated Oocyst One oocyst of Isospora suis contain 2 sporoblasts . E.Debliecki and E .Scabra Life Cycle • • • • • • • • • oocyst→ sporulated oocyst→ sporozoite → trophozoite→ schizont→ merozoite→ gametocytes→ zygotes→ a new oocyst • Two breeding way: • schizogony:schizont→gametocytes • gametogony:gametocytes→zygotes • Two kinds of living environment: • one is feces:oocyst→sporulated oocyst • the other is intestinal epithelium : • sporulated oocyst→zygotes→ a new oocyst Epidemiology • The disease occurs in only piglet.older pigs may get more recessive infection.As the oocyst development needs the higher temperature, so the disease occur in late spring and summer • sources of infections: Infective pigs and feces. Routes of infections This disease is the main gastrointestinal dissemination way. • When oocysts in a waste, pollution eliminated from the feed, water, soil sac or equipment etc, in suitable temperature and humidity piglets will get infectious incubation(潜伏) by the oocysts Symptoms • Diarrhea. • Feces yellow to gray. Beginning feces loose or show paste, as the illness grew worse due to a liquid, occasionally feces three stylistically brown; And often sticks full liquid waste, and will be issued corruption milk samples calculate stink. Coat coarse disorderly, dehydration, angular, increase weight slowly. • A high incidence, mortality is low Isospora suis • 等孢球虫感染猪的 小肠,粘膜上皮发 现的裂殖体形成裂 殖子 Lesions • Piglets records variation is mainly chordapsus, confined by open-stope and ileum, sometimes visible necrotic enteritis, pseudomenbrane loosely adherent in hyperemia of mucous membrane. 黏膜坏死病变的肠粘膜有撒糠样的伪膜 Diagnosis • Clinically 7-21 age of piglets occurrence diarrhoea, after using common antibiotics therapy failed, a suspect about coccidiosis comes. • fecal method:flotation method • Scrape off jejunum and ileum mucous membrane, wipe piece dyed, find made of endogenous growth phase worm body(merozoite、schizont、gametocyte) 球虫病组织学变化小肠粘膜上见不同成熟期 的球虫和小配子体、大配子体及卵囊感染 Treatment&Prevention • Coccidiostat:Toltrazuril • Prevention: • 1、Disinfect the maternity ward:With formaldehyde, glutaraldehyde,ethylene oxide ethane fumigation method disinfection, or basin of peracetic acid fog method, heating flame method disinfection • 2、With amprolium feeding pigs can have good prevention effect • Inactivation treatments of feces 陈红秀 罗川 崔可琦 黎秀英 王睿姣