Pain Consultations 101 Melissa Durham, Pharm.D. September 14th, 2011 Acute vs. Chronic Pain Characteristic Acute Pain Chronic Pain (No Self-Treatment) Relief of Pain Highly Desirable Highly Desirable Dependence & Tolerance Unusual to Medication Common Psychological Component Usually Not Present Often a Major Problem Organic Cause Common Often Not Present Environmental Contributions & Family Involvement Small Significant Insomnia Unusual Common Component Treatment Goal Cure Functionality Assessment of Pain SCHOLAR • Symptoms – Describe the symptoms you are experiencing • Characteristics/Course – Is the pain throbbing, sharp, dull, tingling? Rate the pain on a scale of 1-10 • History – How does it compare to other pain experienced? Has it gotten worse over time? • Onset – When did the pain start? • Location – Where is the pain located? Does it stay localized to one area or does it spread? • Aggravating factors – What makes the pain worse? • Relieving factors – What makes the pain better? Temporary relief of minor aches and pain associated with the common cold Reduction of fever Sore throat Headache (Episodic Tension, Migraine, Sinus) Muscle aches Minor aches and pains of arthritis Acute back pain Menstrual pain Acetaminophen, AKA APAP (Tylenol) Mild-moderate pain, fever, headaches NSAIDs Ibuprofen (Motrin, Advil) Naproxen sodium (Aleve) Mild-moderate pain, headaches, muscle pain, menstrual pain Salicylates Aspirin AKA ASA (Ecotrin, Bayer) Mild-moderate pain, muscle pain, menstrual pain, cardioprotection Topicals (IcyHot, Bengay) Muscle soreness, muscle pain, osteoarthritis Brand Name – Tylenol®, FeverAll® Class – Analgesic/Antipyretic ◦ Not effective as an anti-inflammatory Very few side effects ◦ Liver toxicity a major concern with chronic high doses Very few drug interactions ◦ Warfarin, alcohol DOC in pregnancy/breastfeeding Used mostly for primary and secondary prevention of thrombotic events ◦ Ex. Aspirin 81mg/day Has anti-inflammatory properties, but only at high doses Major side effects are bleeding, GI ulcers, bronchospasm in patients with asthma More DDIs than APAP NOT for use in pregnancy/breastfeeding Counseling point: TAKE WITH FOOD Ibuprofen, naproxen sodium More effective than APAP and ASA for most pain conditions Analgesic and anti-inflammatory effects Major side effects are bleeding, GI ulcers, bronchospasm in patients with asthma, increased blood pressure, fluid retention Generally avoid in pregnancy but OK in breastfeeding Counseling point: TAKE WITH FOOD Used for minor aches and pains of muscles and joints, muscle soreness, osteoarthritis, lower back pain, neuropathy Ben-gay, Icy-hot, Salonpas Methyl salicylate, camphor, menthol, capsaicin Combinations Apply 3-4 times daily for a max of 7 days Do not apply immediately after a hot shower or bath, do not use with a heating pad Wash hands after applying Types of Headache Stress Anxiety Depression Emotional conflicts Fatigue Repressed hostility Excedrin® Tension Headache ◦ 500mg Acetaminophen + 65mg caffeine APAP Ibuprofen Naproxen Other combo products Physical therapy Relaxation exercises Massage Topical Peppermint oil ◦ Applied to forehead and temples Stress Fatigue Oversleeping Fasting, missing a meal Alcohol Changes in barometric pressure or altitude Menses Hormone changes Magnesium deficiency Foods with nitrites, tyramine, phenylalanine, MSG, caffeine Excedrin® Migraine Advil® Migraine Other analgesics will work, NSAIDs probably best Initiate NSAIDS 2 days before menses for menstrual migraine Self-treatment is only for patients who have been diagnosed with migraine by a physician ◦ Acetaminophen 250mg/Aspirin 250mg/Caffeine 65mg ◦ 2 tabs at onset, no more than 2 tabs per 24 hours ◦ Ibuprofen 200mg (liquid filled) ◦ 2 caps at onset, no more than 2 tabs per 24 hours Regular sleeping & eating schedule Avoidance of triggers (food, stress) Cold packs + pressure Lie in a dark, quiet room Keep a headache journal Symptoms of cluster headache Symptoms of migraine headache with no formal diagnosis Chronic tension headache (>15 days/month for > 6 months) Severe pain (pain score 8-10) Signs of infection (fever, purulent discharge, altered mental status) Headache that Lasts more than 10 days Occurs more than 3 times a week Not managed by NonRx dosing Acute Low Back Pain Possible causes Inactive lifestyle Poor posture Improper shoes Excess body weight Poor mattress Poor sleeping posture Improper lifting techniques • • Most back pain disappears with home treatment and self-care Treatment options • NSAIDs • Topical analgesics • Alternating heat/cold • Massage • Chiropractic manipulation • Moderate physical activity when not acutely injured • Chronic low back pain ( > 4 weeks) Refer Sprains – injury to ligaments Strains – injury to muscle or tendons ◦ Overextension of the joint ◦ Ankle inversion most common ◦ Overuse or improper use Symptoms: Pain, bruising, loss of some function, stiffening Treatment ◦ RICE Therapy ◦ NonRx NSAIDS Rest the injured area. Ice the area in 10 minute intervals, 3 – 4 times a day for 1 – 2 days. Compress the area with elastic support. Elevate the area above the heart for 48-72 hours to decrease swelling and pain. Delayed-onset muscle soreness most common and is self-treatable Other types - Refer NonRx treatment: ◦ NSAIDS ATC ◦ Topical Preparations (Salicylates, Camphor, Menthol) Nonpharmacologic Therapies NonRx Therapies ◦ ◦ ◦ ◦ ◦ Low-impact exercise Weight-loss Shock-absorbing shoes Physical and occupational therapy Acupuncture ◦ Tylenol is drug of choice ◦ NSAIDS ◦ Glucosamine & Chondroitin: Not for people with shellfish allergy, may raise blood sugar in diabetics, may increase the effect of warfarin ◦ Topical analgesics/counterirritants OTC treatment options: Midol® Menstrual Complete: (Acetaminophen 500mg/Caffeine 60mg/Pyrilamine 15mg) Midol® Extended Relief (Naproxen sodium 220mg) Midol® Cramps and Body Aches (Ibuprofen 200mg) Midol® Teen Formula (APAP 500mg/Pamabrom 25mg) NonRx NSAIDs are the treatment of choice at MAX OTC doses Heating pads Regular exercise Loose clothing Massage Smoking cessation Do Give advice and make suggestions Determine if nonprescription medications will help Provide resources Suggest options and let people know their pain may be managed ◦ Use common sense ◦ ◦ ◦ ◦ Don’t ◦ ◦ ◦ ◦ Say something you are not sure about Diagnose or suggest specific prescription therapy Recommend self-treatment when not appropriate Give false hope Community Resources Referral Sources: ◦ American Chronic Pain Association (www.theacpa.org) ◦ American Pain Foundation (www.painfoundation.org) ◦ American Headache Society (www.americanheadachesociety.org) ◦ Arthritis Foundation (www.arthritis.org) Referral for pain management: ◦ American Chronic Pain Association at 800-533-3231 ◦ Local hospice or cancer center often know good pain specialists ◦ USC/Norris Comprehensive Cancer Center (323) 865-3000, ask for referral to pain specialist ◦ USC pain center: 323-442-6202 For those without a doctor or insurance: ◦ Local hospital’s social services department or local health department LA Social Services Info Line at 800-339-6993 LAC/USC Referral Line at 323-226-4970 ◦ Patient Advocate Foundation at 800-532-5274 Poison Control: 1-800-222-1222 Questions?