Medicine in the Renaissance Topics • • • • • • Contemporary view of health and illness Illnesses, epidemics, infectious diseases Learned Medicine Knowledge of Anatomy and Physiology Medical education Surgeons and Surgery Contemporary view of health and illness • Hippocratic / Galenic tradition – Hippocrates 450-370 BCE; Galen 129200 CE – Tied disease to the environment • Changes in air or water or planets • Individual, not anatomical Galen and Hippocrates Humoralism Four humors: – Black bile – Yellow or red bile – Blood – Phlegm • An imbalance caused sickness; the environment could affect it Sickness as Invasion • Pollution of the body • Immorality and vice • To “cure”: – Prayer, penance, exclusion Medicine and the body • Body not well understood • Metaphorical terms: – “Balance,” “sympathy,” “rhythms,” – outward marks or signs of inner state • Mental and physical intertwined • Cures: transference, sympathy, purge • Astrology – stars influenced bodies and caused illness – Treatment did not differ Mortality • Curve differs from that of today • Infant mortality often quite high • Most dangerous age of life: – Infancy and early childhood – 1 out of 4 or 5 did not survive 1st year – 50% of mortality occurred before age 10 • Geographical and class divergence • Debate over statistics for death in childbirth Infant mortality, pre-1750 Area England France Germany Scandinavia Spain Switzerland Number of deaths /1000 live births 187 252 154 224 281 283 Michael W. Flinn, The European Demographic System, 1500-1820. Brighton, 1981), 16-17. Cited in Lindemann. Survival rates, pre-1750 Area Number of survivors/1000 live births at age England 1 799 5 668 10 624 15 -- France 729 569 516 502 Switzerland 766 597 533 506 Michael W. Flinn, The European Demographic System, 1500-1820. Brighton, 1981), 16-17. Cited in Lindemann. Childhood illnesses • • • • • • • • • • • Minor illnesses Smallpox Whooping cough Infantile diarrheas Tuberculosis Plague Typhus Injuries that crippled or severely impaired Worm infestations Eye infections Accidents Social and environmental factors • • • • • • • Not straightforward Diet Housing Invasion and civil war; revolt Some diseases attacked the strong (plague) Lepers had a certain immunity to tuberculosis Dyeing, bleaching, tanning, etching, hot metals, fires of forges, butchers’ knives, animals Views of disease: • Survival of childhood made one hardy and resistant • Religious views of pain, illness, deformity • People knew life was fragile Hans Holbein the Younger, Dance of Death. Lyons, 1538 Disease and Epidemics • Causes of disease: – Macroparasites, such as worms: – Microparasites: bacteria, protozoa, viruses • Propagated by: – Air, water, food – Non-human vectors: • Mosquitoes, ticks, fleas, lice Most Important infectious diseases in the period • • • • • • • • • Plague: bacillus Dysentery: bacillus Influenza: virus Smallpox: virus Measles: virus Tuberculosis: bacillus Typhus: bacterium Syphilis: bacterium Malaria: protozoan parasites Medical Education • • • • • • Learned Medicine Medical universities Clinics and clinical instruction Medical students Training surgeons Midwifery and man-midwifery Context: Galenic Medicine • 13th c.: transmitted through Arabic sources – significant parts missing • • • • • • An adaptable system Not of Galen himself (129-200 CE) Known by learned and lay people Natural causes and non-supernatural cures Rational and learned Stressed philosophy Renaissance Galenism • Was rational and logical • Reform took place over 3 centuries: – 16th century anatomical revolution – Paracelsus’ attack on medical ideas – 17th century scientific revolution – Rise of iatromechanical and iatrochemical medicine Paracelsus (1493/94-1541) • • • • • Attacked established medical community Rejected Galenic humoral theory Relied on experience and practice Traveled as an army surgeon Father physician trained him in: – botany, mineralogy, mining, natural philosophy • Studied in Northern Italy? – no record of A degree • Turbulent life, followed a pattern Paracelsus and medicine Many kinds of patients from all strata of society Firsts: • Described miners’ diseases as occupational • Distinguished congenital syphilis • Noted mercury had to be in small doses to cure syphilis • Medical account of chorea (nervous disorder) • Linked goiter and cretinism to thyroid • Said disease has external cause (chemical or mineral) • Said disease was localized • Sought proper chemical treatments Paracelsus “In this portrait Paracelsus is shown surrounded by various philosophical symbols, including his famous sword. From Paracelsus: Etliche Tractaten, zum ander Mal in Truck auszgangen. Vom Podagra und seinem Speciebus (Coln, 1567). Washington University Collection.” Allen G. Debus E. Feynon, Der Barmhertziger Samariter Renaissance instruction in preparation of chemicals. From Annibal Barlet, Le Vray et methodique cours de Chymie (Paris, 1653) New Anatomical Studies • Galenic medicine still current • Dissections of cadavers recent • Vesalius (Belgian, humanistic, medical studies in Paris and Padua) • Published De Humani Corporis Fabrica Libri Septem, 1543 • Woodcuts done by a student of Titian • Corrected 200 errors of Galen • Revolutionary • Beginning of modern medicine Andreas Vesalius (1514-1564) Andreas Vesalius, De Humani Corporis Fabrica Libri Septem, 1543 M. R. Columbus, De re anatomica, Venice, 1559. Wellcome Trust Medical Education • Universities trained physicians • Lay physicians had no formal training • Surgeons, midwives: – Gained expertise through apprenticeships • Some physicians were autodidacts • Eventually there were hospitals and private schools Medical Universities • 12th and 13th centuries in Italy, France, England, Iberia, • 14th century: Prague, Wittenberg • In Italy: – Salerno, Bologna, Padua, Ferrara • In France: – Paris, Montpellier Basis of education • Galen’s work fully known only in 15th century • Pre-printing, MSS and texts were limited • Professors lectured from the major texts: – – – – Articella: gathering of major Galenic and Hippocratic texts Commentaries: on the major texts (by Professors) Consilia: Case studies All were studied in terms of solving differences of opinion • Practice under supervision • Attendance at public dissections – first in Bologna, 1316 Renaissance Medical Education • Drew on and changed Medieval education • Relied on repetition of topics • Post 15th-century: – Medical texts for students – Access to anatomical prints – Physicians had libraries of medical texts – By 18th century, more emphasis on bedside practice Clinical Education • Arguments over the “birth of the clinic” and rise of hospital medicine • Protoclinics in the 16th and 17th centuries • 1540s Padua • 1630s Leiden • 1720s Halle • 1730s Strasbourg • 1740s Edinburgh • 1750s Vienna Private Medical Education • • • • English universities: Oxford and Cambridge Hospital at London Modern medicine developed differently Private lessons: – In anatomy and dissection – In medical education • Private medical career more consumer driven than on the continent Medical Students • Educational objectives: – To produce physicians – To maintain learnedness – To separate them in social status from the lower classes • Recruited from families of: – Bourgeoisie, lawyers, churchmen. – Rarely from noble or poor families – Poorer students usually had benefactors Surgeons and their training • • • • • • • • Surgeons were not trained in universities Trained as artisans within a guild system Was there a strict hierarchy? In social status Many physicians did not take courses but were trained as apprentices Some university-trained physicians never finished their degrees Surgical training could be as rigorous and complex The difference: cultural status Eventually, surgery and physic will merge Surgeons and guilds • Guilds as institutions • Unique systems of education and requirements for completion of training • Licensed their candidates • Sometimes included surgeons, barbersurgeons, and bathmasters: conflicts • For a fee, the apprenticeship lasted 4 years • Then, a longer Journeyman period • Return home to be tested and licensed • Drawn from families of surgeons, artisans, pastors, apothecaries • Not from prosperous families or poor families Surgical treatments • From 15th c: move to more active surgery • Military revolution demanded new medical techniques • Ambroise Paré (1510-90). – – – – – – Apprenticed as a barber-surgeon Army surgeon in Habsburg-Valois conflicts Wrote on treatment of gunshot wounds Wrote on vascular ligature Wrote on how to correct breach position in childbirth 1564: Book on general surgery Rise in surgery Military surgery had civilian applications • 1549-99: Skin grafting introduced – Branca family secret • 1620s: Forceps – Chamberlen family secret • mid 16th c: lithotomy, Colot family secret • 16th c: Cataract surgery • 18th c: surgery separated from barbersurgeons Hieronymus Brunschwig, Das Buch der Cirurgia. Strassburg, 1497. Countway Library of Medicine, Harvard University Leg surgery. Buch der Cirurgia Hantwirckung der Wundartzny, Hieronymus Brunschwig, 1497. Major, 434 First illustration of amputation. Feldtbuch der Wundartzney, Hans von Gerssdorff, 1517. Military surgery: removing an arrow. Possibly from Feldtbuch der Wundartzney, Hans von Gerssdorff, 1517 Injuries soldiers could suffer on the battlefield. "Wundenmann aus Eyn gut [well] artzney" ca. 1525 Brain Surgery Buch der Cirurgia Hantwirckung der Wundartzny, Hieronymus Brunschwig, 1525 Reduction of dislocated arm Hans von Gersdorf, Feldbuch der Wundartzney, Strassburg, 1530. Wellcome Trust Medical Photographic Library Surgery on a Stomach Wound Hans von Gersdorf, Feldbuch der Wundartzney, Strassburg, 1540. Wellcome Trust Medical Photographic Library Surgical Instruments Hans von Gersdorf, Feldbuch der Wundartzney, Strassburg, 1540. Wellcome Trust Medical Photographic Library Cataract Surgery. Georg Bartisch, das ist Augendienst, 1583. Major, 44142 M. R. Columbus, De re anatomica, Venice, 1559. Wellcome Trust From Paracelsus, Opus chyrurgicum ... und Artzney Buch (Franckfurt am Mayn, 1565) Midwifery • • • • Midwives delivered most babies: 20th c. Spprentice system Experience desirable; midwife families In early 16th century, – some had to attend public dissections – or be instructed by physicians or surgeons • Some produced manuals of instruction • Some cities held courses for men and women midwives; men after 1700 • Surgeons often helped with difficult births Midwife Aiding at a Birth. Wellcome Trust Medical Photographic Collection A seated woman giving birth aided by a midwife and two other attendants, in the background two men are looking at the stars and plotting a horoscope. Woodcut, 1583[?]. Obstretics Early Printed Medical Works Herbolarium de virtutibus herbarum, Vincenza, 1491. Countway Library of Medicine, Harvard University Hortus sanitatis, Mainz, 1491. Countway Library of Medicine, Harvard University John de Ketham, Fasciculus medicinae. Lier, Milan,1491. Wellcome Trust. Chiromantia, Venice, 1493. Countway Library of Medicine, Harvard Joseph Grünpeck, Ein hubshcer Tractat von dem Ursprung des Bösen Franzos (A fine treatise on the Origin of the French Evil [syphilis]), Nuremburg, Caspar Hochfeder, c. 1497. Countway Library of Medicine, Harvard Univ. Jerome of Brunswick, The vertuose boke of disyllacyon of the waters of all manere of herbes, London, 1527. Leonardo Fuchs, De historia stirpium commentarii, 1542. Poppy. Sources • Mary Lindemann, Medicine and Society in Early Modern Europe (Cambridge: Cambridge University Press, 1999). Some text slides • Nancy G. Siraisi, Medieval and Early Renaissance Medicine: An Introduction to Knowledge and Practice (Chicago: University of Chicago Press, 1990). Summary of text, images • Mario Biagioli, Harvard University, History of Science 161: The Scientific Revolution. Notes on Paracelsus • National Library of Medicine: Exhibit on Paracelsus: Five Hundred Years. • From Homer to Vesalius: Exhibit at Univ. of Virginia Medical School. Images. • University of Kansas Medical School. Ralph Major’s photographs. • Wellcome Trust Medical Library. Images.