STEMI/STROKE BOOT CAMP “Time is Muscle” Paul T. Frantz, MD Medical Director, Cardiac Services Carilion Clinic Agenda • “Time is Muscle” – what is the science behind this statement • Case Reviews – with ‘take home’ messages • Q&A Full Disclosure Statement: Dr. Frantz receives no reimbursement from any of the companies or products sited in his presentation Atherothrombosis: Thrombus Superimposed on Atherosclerotic Plaque Adapted with permission from Falk E, et al. Circulation. 1995 ;92:657-671. Slide reproduced with permission from Cannon CP: Atherothrombosis slide compendium; www.theheart.org Treatment Delayed is Treatment Denied Symptom Recognition Call to Medical System PreHospital ED Cath Lab Increasing Loss of Myocytes Delay in Initiation of Reperfusion Therapy Antman EM et al. Circulation, 2004 11 Normal Right Coronary Arteriogram Case # 1 “When all the stars are aligned” • 54 y.o male with sudden onset chest pain before going to work • Called 9-1-1, Fort Lewis crew responded • c/o nausea, vomiting, right shoulder pain • Cool and diaphoretic; BP 90/40 P 56 (weak) • Loaded & IMI identified on 12 lead EKG • Field Heart Alert called “ETA 10 minutes” Field EKG @ 8:04 AM Time Sequence for Case # 1 Dispatched Arrived at Scene Arrived at Patient Field EKG Transport Heart Alert Called (“ETA 10 min”) Arrived at CCL (direct admit) Balloon Time Door to Balloon Time EMS Contact to Balloon Time 7:52 7:56 7:57 8:04 8:07 8:23 8:35 9:01 26 minutes 64 minutes Cardiac Catheterization/PCI Normal Left Coronary Arteriogram Case # 2 “Reinforcing That Time is Muscle” • 61 y.o. male (R.M.) c/o severe c.p. beginning about 4:30 PM • Called 9-1-1 after 5:00 and CPTS ground crew requested LG 10 on standby • Clinical presentation and12 lead by ground crew suspicious for MI (rapid AF with wide complex QRS); LG 10 launched • Given ASA, NTG, adenosine and fluid bolus • Repeat 12 lead suspicious for MI and pt transferred to CRMH by air • Remained hypotensive (100/72) with rapid, weak pulse during transport • After evaluation in ED, Heart Alert called CPTS 2nd EKG on ground CPTS 1st EKG on ground CPTS 1st EKG on ground LG 10 EKG while in air Time Sequence for Case # 5 Standby Request for LG 10 Launch Request Lift off Arrive at Scene 17:20 17:55 17:59 18:23 Transport Arrive CRMH Arrived at ED 18:34 18:50 19:00 Heart Alert called Balloon Time Door to Balloon Time 19:30 20:33 93 minutes HA to Balloon Time EMS Contact to Arrival CCL 63 minutes 130 minutes Cardiac Catheterization/PCI Bottom Line………………… the old mantra rings true! System saves time! System saves muscle! Systems saves lives! 41 Treatment Delayed is Treatment Denied Symptom Recognition Call to Medical System PreHospital ED Cath Lab Increasing Loss of Myocytes Delay in Initiation of Reperfusion Therapy Antman EM et al. Circulation, 2004 42