BREAST CANCER SCREENING PROGRAMS AND STRATEGIES IN CANADA ENVIRONMENTAL SCAN March 2013 Background Quarterly, the Canadian Partnership Against Cancer collects information from the provinces/territories on the status of population-based breast cancer screening programs and/or strategies. The information is collected through provincial and territorial leads represented on the National Committee of Canadian Breast Cancer Screening Initiative supported by the Canadian Partnership Against Cancer. March 2013 Presentation Outline Canadian Task Force on Preventive Health Care Guidelines Provincial and Territorial Guidelines Breast Cancer Screening Program Distribution and Administration Recruitment and Recall Quality Assurance Breast Cancer Data Reported Breast MRI (High Risk Screening Guidelines) March 2013 Canadian Task Force on Preventive Health Care Guidelines The Canadian Task Force on Preventive Health Care (2011) recommends the following for breast cancer screening: Mammography For women aged 40-49, routine screening not recommended (Weak recommendation; moderate quality evidence) For women aged 50-69, routine screening every 2 to 3 years (Weak recommendation; moderate quality evidence) For women aged 70-74, routine screening every 2 to 3 years (Weak recommendation; low quality evidence) Magnetic Resonance Imaging Routine screening not recommended (Weak recommendation; no evidence) March 2013 Canadian Task Force on Preventive Health Care Guidelines (Cont’d) Clinical Breast Exam Routine screening for breast cancer is not recommended when performing clinical breast exam alone or in conjunction with mammography (Weak recommendation; low quality evidence) Breast Self Exam Routine practice of breast self exam is not advised by the Task Force (Weak recommendation; moderate quality evidence) March 2013 Breast Cancer Screening Programs: Provincial and Territorial Guidelines Start Age Interval Stop Age Nunavut Northwest Territories Yukon British Columbia Alberta Saskatchewan Begin at age 50 (age 40 – 49 accepted by physician referral and self –referral but not actively recruited) For women aged 40-49 - annual recall For women aged 50-69 - biennial recall For women aged 70+ - biennial recall 79 Begin at age 40 For women aged 50-69 - biennial recall For women aged 70+ - biennial recall 70+ Begin at age 40 (<40 accepted with physician referral) For women aged 40-49 - annual recall For women aged 50-69 - biennial recall For women aged 70-79 - biennial recall 79 (age 80+ only with physician referral) Begin at age 50 (age 40-49 accepted with physician referral for the first screen) For women aged 40-49 - annual recall For women aged 50-69 - biennial recall 70+ For women aged 50-69 - biennial recall For women aged 70-74 - biennial recall (only if previously enrolled in the program) 75+ Begin at age 50 (age 49 accepted on the mobile if turning 50 in same calendar year) Manitoba Begin at 50 (ages 40-49 accepted to mobile unit only with physician referral) For women aged 40-49 - biennial recall For women aged 50-69 - biennial recall For women aged 70-74 - biennial recall 75+ Ontario Begin at age 50 (ages 30-49 accepted if high risk and referred by physician) For high risk women aged 30-49 - annual recall For high risk women aged 50-69 – annual recall For women aged 50-69 - biennial recall For women aged 70-74 - biennial recall 75+ Breast Cancer Screening Programs: Provincial and Territorial Guidelines (Cont’d) Start Age Québec New Brunswick Nova Scotia Prince Edward Island Newfoundland & Labrador Begin at age 50 (accept ages 35-49 only with physician referral if done at a program screening centre) Interval For women aged 50-69 - biennial recall Stop Age 69 (age 70+ only with a physician referral at a program screening centre) Begin at age 50 (age 40-49 accepted only with physician referral) For women aged 50-69 - biennial recall 69 (age 70+ only with a physician referral) Capacity to increase to age 74 Begin at age 40 For women aged 40-49 - annual recall For women aged 50-69 - biennial recall 70+ Begin at age 40 (ages 30-39 accepted if high risk and referred by physician) For women aged 30-39 - annual recall For women aged 40-49 - annual recall For women aged 50-69 - biennial recall For women aged 70-74 - biennial recall 74 Begin at age 50 (age 40-49 accepted only with physician referral) For women aged 50-69 - biennial recall 69 (age 70+ only if previously enrolled in the program) March 2013 Distribution of mammography and CBE among breast screening programs Province/Territory (Program Disribution) Mammography alone Yukon Territory Clinical Breast Examination & Mammography (1990) Northwest Territories (2003) British Columbia (1988) No Organized Program Nunavut Newfoundland & Labrador (1996) Alberta (1990) Saskatchewan Manitoba (1990) (1995) Quebec (1998) Ontario (1990) Prince Edward Island (1998) New Brunswick (1995) Nova Scotia (1991) Breast Cancer Screening Program Administration Program Start Date Program Name Agency Responsible for Program Administration Nunavut Northwest Territories 2003 2008 Breast Screening Program, Stanton Territorial Health Authority Breast Screening Program, Hay River Health and Social Services Authority Stanton Territorial Health Authority Hay River Health and Social Services Authority Yukon 1990 Yukon Mammography Program Government of Yukon British Columbia 1988 Screening Mammography Program of British Columbia BC Cancer Agency Alberta 1990 Alberta Breast Cancer Screening Program Alberta Health Services Saskatchewan 1990 Screening Program for Breast Cancer Saskatchewan Cancer Agency Manitoba 1995 BreastCheck Cancer Care Manitoba Ontario 1990 Ontario Breast Screening Program Cancer Care Ontario Québec 1998 Québec Breast Screening Program Ministère de la Santé et des Services sociaux New Brunswick 1995 New Brunswick Breast Cancer Screening Services New Brunswick Cancer Network (NB Ministry of Health) Nova Scotia 1991 Nova Scotia Breast Screening Program Government of Nova Scotia Prince Edward Island 1998 PEI Breast Screening Program Government of Prince Edward Island Newfoundland and Labrador 1996 Breast Screening Program for Newfoundland and Labrador Eastern Health, Cancer Care Program Participant Recruitment Doctor referral Self-referral Initial letter of invitation Age group to which letter is sent Nunavut Northwest Territories Yukon British Columbia 50-69 Alberta 50-69 50-70+ 50-69 50-69 (not all regions) 50-69 Saskatchewan Manitoba Ontario Québec New Brunswick Nova Scotia* Prince Edward Island Newfoundland and Labrador * NS initially started sending out letters of invitation; however, they have since stopped due to capacity issues. March 2013 Recall Following a Normal Mammogram Send out recall letters Coordination of recall for women following a normal screening episode performed by Any additional follow-up to first recall letter after no reply Age group for recall 40-79 Nunavut Northwest Territories Centralized management (Program or Agency) Yukon Screening centre British Columbia Centralized management (Program or Agency) 40-79 (AHS Screen Test only) Centralized management (Program or Agency) 40-69 Saskatchewan Centralized management (Program or Agency) 50-70+ Manitoba Centralized management (Program or Agency) 50-74 Ontario Regional coordination centres/ Screening centre 50-74 Québec Regional coordination centres 50-69 (not all regions) Screening centre 50-69 (postcard) Centralized management (Program or Agency) 40-69 Prince Edward Island Screening centre 40-74 Newfoundland and Labrador Screening centre 50-74 Alberta New Brunswick Nova Scotia 40-79 March 2013 High Breast Density Recall and Recommendations Five provinces and territories recall women based on high breast density Recommendations following a high breast density reading varies across P/Ts Automatic annual recall based on breast density Value considered high breast density Recommendation for high breast density levels > 75% Annual recall >75% Annual recall >75% Annual recall Nova Scotia >75% Annual recall Newfoundland and Labrador >75% Annual recall Northwest Territories Alberta Ontario March 2013 Association of Screening Program/Centre with Diagnostic Follow-Up Assessment of abnormal results (radiological or histopathological) occurs within the screening program Screening centre books diagnostic assessments Medical prescription needed for each diagnostic assessment Radiological/ pathological assessment teams have access to screening reports Nunavut Northwest Territories Yukon Facilitates diagnostic referral British Columbia (Varies by site) (Varies by site) Saskatchewan Manitoba Ontario (Varies by site) Québec (Varies by site) (Varies by site) Nova Scotia Prince Edward Island Newfoundland and Labrador Alberta New Brunswick (On request) Quality Assurance: General Conduct a review of screening films/digital images of interval cancers* Conduct a review of missed at assessment cancers Require a ‘double read’ of a portion of all screens Have a questionnaire to evaluate client satisfaction Conduct analyses to estimate the effect of organized breast screening on mortality Nunavut Northwest Territories Yukon British Columbia Alberta** Saskatchewan Manitoba Ontario (Done at individual centres) Québec New Brunswick Nova Scotia (Provincial Cancer Report) *** (periodically) (in the process) Prince Edward Island Newfoundland and Labrador *Classify cancer as either true interval or missed at screening **Alberta Health Services Screen Test sites only ***NS review of all interval cases 1991 to 2004 and CD of various cases are sent to all screening radiologists. Now with full field digital this will be competed electronically. Quality Assurance: Client Satisfaction Surveys NWT, BC, AB, MB, NS and NL evaluate client satisfaction on an ongoing basis Table: Specific information collected when evaluating client satisfaction per province/territory Mammography exam Particular Screening Centre Organized Screening Program Northwest Territories British Columbia Alberta Manitoba Nova Scotia Newfoundland and Labrador March 2013 Quality Assurance: Evaluation of Radiologist Performance Most P/Ts evaluate radiologists on their level of performance on an annual basis with the exceptions of YK and PEI. NB collects this data but does not report on it Table: Specific information collected when evaluating radiologist performance per province/territory Positive Predictive Value (PPV) Abnormal call rate Cancer detection rate Interval cancers Northwest Territories British Columbia Alberta Saskatchewan Manitoba Québec Nova Scotia Newfoundland and Labrador Ontario General performance reviews Other (specified) Sensitivity/ Specificity Sensitivity/ Specificity Sensitivity/ Specificity and One year recall rate Sensitivity/ Specificity Table: Specific volume requirement for radiologists per province/territory NL NS NB QC ON MB SK AB BC NT 1,500 / year 480 / year** 2,500 / year 480 / year 2,500 / year 1200/ year** *All radiologists greatly exceed this number **Includes diagnostic and screening mammograms 500/ year 1,000 / year 1,000 / year* 3,000 / year Quality Assurance: Vital and Cancer Registry-Linkages with Provincial Registries Collection of ‘Vital Status’ variable Collection of ‘Date of Death’ variable Collection of cancer stage (TNM or Collaborative stage) or other cancer variables Nunavut Northwest Territories ** ** British Columbia Alberta * * Saskatchewan Manitoba Ontario *** Yukon Québec New Brunswick Nova Scotia Prince Edward Island Newfoundland and Labrador *Through provincial client registry **Decreased lists are provided to WGH monthly ***linkage for post-screen cancer information only March 2013 Mammography Screening Program: Vital and Cancer Registries – TNM or Collaborative Stage For the provinces and territories that do not currently link with provincial cancer registries to collect cancer stage (TNM or Collaborative Stage) or other cancer variables, it may still be possible: For the collection of post-screen cancer information (BC, QC, NS*) For the collection of cancer and stage information (BC, NS*) *Note: Both linkages are possible in NS; however, an agreement has not yet been established For YK it is unknown if this is possible March 2013 Breast MRI: High Risk Guidelines Currently there are five provinces (BC, AB, ON, NS, NL) that have developed standard guidelines for MRI referral Table: The criteria or evidence that MRI referral is based upon per province Self-reported family history (>=2) of breast cancer (first degree relative) British Columbia Selfreported family history of BRCA 1/2 Genetic testing BRCA 1 or 2 Risk of breast cancer >20% (scored by validated assessment tools) Chest irradiation between the ages of 10 and 30 years Li-Fraumeni syndrome, Cowden syndrome, or BannayanRileyRuvalcaba syndrome **** Alberta Ontario * ** *** ** Nova Scotia Newfoundland and Labrador Prince Edward Island >=3 * First degree relative ** >25% using validated assessment tool *** Chest irradiation before age 30 and at least 8 years ago **** BC includes the following syndromes: Li Fraumeni Syndrome, Cowden’s Syndrome, HDGC (CDH-1), Peutz-Jegher’s Syndrome March 2013 Future Implementation of MRI Ontario has implemented an MRI screening component to its organized screening program for women considered at high risk for breast cancer. BC, NS and AB have established guidelines for the use of MRI among women considered to be at elevated risk (i.e. in BC the women considered are confirmed cases of BRCA1 and BRCA2 mutation only). For more information on MRI guidelines for NS please visit www.breastscreening.ns.ca NL is exploring the appropriateness of using MRI among women considered to be at elevated risk March 2013 Reference Slide Please use the following reference when citing information from this presentation: Breast Cancer Screening in Canada: Programs and Strategies. Cancer View Canada. Available at: [Enter Link], Accessed: [Enter Date Accessed]. March 2013