Carl Zeiss Meditec Developing innovation means finding what moves people. Presentation title XXX Page 2 Version xx/200y 1.1 Our Vision Our vision is to contribute to improvements in the lives of as many people as possible, re-establish their quality of life and preserve this quality well into old age. Presentation title XXX Page 3 Version xx/200y 1.1 Our Mission We live in an information-rich, fast-paced mobile society. Our mission is to provide the solutions that allow everybody to enjoy a high quality of life in our modern world. Everyone should be able to have best possible vision throughout their lifetime and the possibility of enjoying mental health and mobility. Presentation title XXX Page 4 Version xx/200y 1.1 160 Years of Excellence 1846 Carl Zeiss opens a workshop for precision mechanics and optics in Jena. 1847 Production of microscopes begins. 1889 Founding of the Carl Zeiss Stiftung by Ernst Abbe. 1945 Partial destruction of the Zeiss works during World War II. Subsequent partition of the company into Carl Zeiss “Optische Werke. Oberkochen” in West Germany and the state-owned enterprise “VEB Carl Zeiss Jena” in East Germany. 1971 Signing of the London Agreement governing the use of the name Carl Zeiss and trademarks containing the word “Zeiss”. 1991 Reunification of the two separated companies. Carl Zeiss acquires Humphrey Systems, a major manufacturer of ophthalmic diagnostic instruments. 1996 The 150th anniversary of the company Carl Zeiss. 2000 Carl Zeiss is the world market leader in microscopes, industrial measuring technology, lithography optics and opthalmic instruments. 2002 Carl Zeiss Meditec AG emerges as a public entity from the merger between the Ophthalmology Division of Carl Zeiss AG and Asclepion Meditec AG, a manufacturer of state-of-the-art refractive lasers. Shares are traded on the Frankfurt Stock Exchange. 2004 Carl Zeiss Meditec (CZM) acquires Laser Diagnostic Technologies, manufacturer of a glaucoma diagnostic instrument. 2005 CZM acquires Ioltech, a specialist in intraocular lenses. 2006 CZM becomes the leader in surgical visualization systems as a result of the integration of Carl Zeiss Surgical. 2007 CZM further strengthens its position in the IOL business by acquiring Acri.Tec AG. Presentation title XXX Page 5 Version xx/200y 1.1 Solid Presence Oberkochen, Germany Jena, Germany Madrid, Spain Presentation title XXX Munich, Germany Dublin, CA USA La Rochelle, France Page 6 Le Pecq, France Tokyo, Japan Hennigsdorf, Germany Version xx/200y 1.1 Gold Standard Products: Quality you can count on HFATM Perimetry Presentation title XXX IOLMaster® Biometry Page 7 Stratus OCTTM Retina Imaging Version xx/200y OPMI® Pentero® Surgical Microscope 1.1 Social Responsibility We support organizations that are committed to fighting illness in the poorer regions of the world. • Vision 2020 – The Right to Sight Striving to save the sight of 100 million people by 2020. Carl Zeiss is a long term partner, providing education, training, marketing, public relations, technical support and financial sponsorship. • Christian Blind Mission CBM acts upon the needs and rights of people with disabilities; 18 million people worldwide benefit from CBM's support. • World Federation of Neurosurgical Societies - WFNS "Microneurosurgery for patients all over the world" – despite financial obstacles. • * PriorDonations of ophthalmic equipment to Acri.Tec acquisition (Mercy ships, India, etc.) Presentation title XXX Page 8 Version xx/200y 1.1 What We Do in Ophthalmology Provide leading edge technology for comprehensive management of ophthalmic disease from diagnosis through treatment and follow-up Example: Cataract Diagnosis Treatment Visante® OCT IOLMaster® Surgical Microscopes IOLs and Consumables Follow-Up Visante OCT VISULAS YAG Laser III IOLs are not for sale in the USA. Presentation title XXX Page 9 Version xx/200y 1.1 Solutions for the Four Main Ophthalmic Diseases We Develop Innovative, Advanced Devices for the Four Main Ophthalmic Syndromes Refraction Retina Cataract Diagnosis Treatment Follow-Up Glaucoma IOLs are not for sale in the USA. Presentation title XXX Page 10 Version xx/200y 1.1 Refractive Solutions Anterior Segment Imaging Visante® OCT Refractive Surgery Systems VisuMax® MEL80™ WASCA® Analyzer CRS-Master® ATLAS® Surgical Microscopes OPMI Lumera® Digital Visualization Phakic Refractive Lenses PRL™ 100/101 PRL™ 200 Epi.Lens® Slit Lamps SL 115 SL 120 SL 130 IOLs, WASCA Analyzer, and CRS-Master are not for sale in the USA. Presentation title XXX Page 11 Version xx/200y 1.1 Refractive Solutions Anterior Segment Imaging and Biometry Visante® OCT – High resolution, non-contact optical coherence tomography Refractive Surgery System VisuMax®– Transfer patients between VisuMax femtosecond system and the MEL80™ excimer laser with a pivoting patient table. MEL80 – A unique workflow for refractive surgery and excellent clinical outcomes. WASCA® Analyzer – High-resolution wavefront aberrometry. CRS-Master®– Provides full spectrum of customized treatment options in combination with MEL80 excimer laser. Combines conventional refractive surgery with wavefront- and topography-guided surgery. ATLAS® – Displays higher-order corneal aberrations, providing valuable insight for patient education and treatment planning. IOLs, WASCA, and CRS-Master are not for sale in the USA. Presentation title XXX Page 12 Version xx/200y 1.1 Refractive Solutions Surgical Microscopes OPMI Lumera® – Surgical microscope with Stereo Coaxial Illumination (SCI™) providing revolutionary red reflex technology. Digital Visualization – Encompassing the MediLive® family of products. Slit Lamps SL 115 – Superb optics for diagnosis, routine examinations and contact lens fitting. SL 120 – Ultimate in performance for diagnosis and documentation. SL 130 – For the full spectrum from diagnosis to therapy. Presentation title XXX Page 13 Version xx/200y 1.1 Refractive Solutions Visante® OCT – Anterior segment imaging & Biometry, V 2.0 Superb cross-sectional images of the entire anterior chamber. New software modules significantly enhance and expand the imaging platform's capabilities: – Software version 2.0 provides a Global – Pachymetry Map and image quality enhancement. – Refractive Tools Software Module features additional LASIK tools and a phakic IOL template to simulate placement. – Irido-Corneal Tools Software Module features AC angle metrics for narrow angle quantification. Presentation title XXX Page 14 Version xx/200y 1.1 Refractive Solutions ATLAS® model 9000 corneal topography system Leveraging proven Placido disk technology, the next-generation ATLAS is a compact, all-in-one system that provides unmatched accuracy and ease of use. New SmartCapture™ Image Analysis Technology enhances clinical accuracy. Zernike corneal wavefront analysis helps optimize aspheric IOL selection. Presentation title XXX Page 15 Version xx/200y 1.1 Cataract Solutions Optical Biometry IOLMaster® Intraocular Lenses (IOLs) XL Stabi ZO® Invent ZO® Acri.LISA® Acri.Smart® XL Stabi® XL Stabi® Sky XL Octo® Sky Bigbag® MF4® Hydromax® Cataract Diagnostics ATLAS® Ophthalmic Lasers VISULAS YAG III VISULAS YAG III Combi Slit Lamps SL 115 SL 120 SL 130 Ophthalmic Viscoelastic Devices (OVDs) VisThesia™ / VisThesia™ Light TwinVisc® Gelbag® / Gelbag Plus® Ophthalin™ / Ophthalin Plus™ Endogel® Acri.Hylon® / Acri.Hylon Plus® Acri.Viscose® Surgical Microscopes OPMI Lumera® OPMI Lumera® T Digital Visualization IOLs are not for sale in the USA. Presentation title XXX Page 16 Version xx/200y 1.1 Cataract Solutions Optical Biometry IOLMaster® – Precision non-contact optical biometry. Corneal Topography ATLAS® – Displays higher-order corneal aberrations, providing valuable insight for patient education and treatment planning. Ophthalmic Lasers VISULAS YAG III - The new dimension of disruption. VISULAS YAG III Combi - Complete laser therapy system for photocoagulation and photodisruption. Slit Lamps SL 115 – Superb optics for diagnosis, routine examinations and contact lens fitting. SL 120 – Ultimate in performance for diagnosis and documentation. SL 130 – For the full spectrum from diagnosis to therapy. Presentation title XXX Page 17 Version xx/200y 1.1 Glaucoma Solutions Perimetry Humphrey® Field Analyzer (HFA) II-I Guided Progression Analysis™ (GPA) SITA-SWAP™ HFA-NET Pro™ & HFA-NET™ Humphrey Matrix® Humphrey FDT® Scanning Laser Polarimeter GDx™ Guided Progression Analysis Surgical Microscopes OPMI Lumera® OPMI Lumera® T Invertertube™ Digital Visualization Ophthalmic Lasers VISULAS YAG III VISULAS YAG III Combi Glaucoma Drain T-Flux® NV Optical Coherence Tomography Cirrus™ HD-OCT Stratus OCT™ Guided Progression Analysis (GPA) Fundus Cameras FF450plus with VISUPAC® VISUCAM NM/FA VISUCAM PRO NM Presentation title XXX T-Flux NV is not for sale in the USA. Page 18 Version xx/200y 1.1 Glaucoma Solutions Perimetry: Humphrey® Field Analyzer HFA II-i – The Gold Standard in perimetry for more than 20 years. Guided Progression Analysis™ (GPA) – Single page analysis that allows clinicians to determine the stage of disease and the rate of progression, and assess the future risk of vision loss. SITA-SWAP™ - Blue-yellow threshold testing in just three to six minutes. HFA-NET Pro™ & HFA-NET™- Connect your HFA II-i series field analyzer to (Electronic Medical Record) EMR systems or your office network to increase practice efficiency. Humphrey Matrix® – Frequency doubling technology for early detection and longterm management Humphrey FDT® – Doubling the opportunity for early glaucoma detection Presentation title XXX Page 19 Version xx/200y 1.1 Glaucoma Solutions Scanning Laser Polarimeter GDx™ – for early detection and management of glaucoma Guided Progression Analysis™ – Easy identification of disease progression Optical Coherence Tomography Cirrus™ HD-OCT – High definition spectral domain imaging Stratus OCT™ – Comprehensive glaucoma and retinal imaging and analysis Guided Progression Analysis™ – Easy identification of disease progression Fundus Cameras FF450plus with VISUPAC® – Multiple image overlay, merge and graphic functions provide a broad range of tools. VISUCAM NM/FA / VISUCAM PRO NM - Fundus cameras that can photograph through undilated pupils as small as 3.3mm Presentation title XXX Page 20 Version xx/200y 1.1 Glaucoma Solutions Humphrey® Field Analyzer II-i with GPA, HFA-NET™ and EasyConnect™ (RCT) Premier automated perimeter for examining a patient’s visual field. Included in all systems are: STATPAC2 - the language of perimetry that is accepted worldwide VFI (Visual Field Index)-Powered Guided Progression Analysis™ (GPA) Software for trend analysis of patient’s overall visual field history and easy identification of disease progression HFA-NET connectivity license with EasyConnect Remote Configuration Tool (RCT) enables you to easily network, configure, and synchronize your HFAs. Optional SITA–SWAP™ reduces blue-yellow threshold test time to just 3-6 minutes to increase practice workflow. Presentation title XXX Page 21 Version xx/200y 1.1 Glaucoma Solutions Humphrey Matrix® – Visual field instrument Patented WelchAllyn® Frequency Doubling Technology provides the eye care professional with an ideal tool to detect and characterize visual field changes for basic glaucoma management. Full threshold test strategies include up to 69, 5º x 5º frequencydoubled stimuli that localize and fully characterize visual field defects. STATPAC-like analysis provides doctors with familiar tools to make confident diagnoses. Presentation title XXX Page 22 Version xx/200y 1.1 Glaucoma Solutions GDx™ – Scanning laser polarimeter Designed and optimized specifically for early detection and management of glaucoma. Compares each patient’s RNFL measurements to a large, agestratified, multi-ethnic normative database. Nerve Fiber Index (NFI) generated by neural network techniques helps to determine the likelihood of glaucoma. Easy to operate with highly repeatable measurements even between perators. Fast, never requires dilation and features a graphic printout that is easily explained to patients. Presentation title XXX Page 23 Version xx/200y 1.1 Glaucoma Solutions Cirrus™ HD-OCT – High definition spectral domain imaging Exquisite high definition images and optimized workflow. Advanced optics enable examination of patients even with cataracts or pupils as small as 2.5mm. Mouse Driven Alignment™ provides image capture and analysis in just a few clicks. Real-Time Registration™ assures precise visit-to-visit registration and excellent reproducibility. Presentation title XXX Page 24 Version xx/200y 1.1 Glaucoma Solutions Stratus OCT™ – Optical coherence tomography, V 5.0 Clinically proven diagnostic insight across a broad spectrum of ophthalmic conditions. Guided Progression Analysis™ (GPA) – Plots a linear regression analysis of average RNFL thickness data and reports statistically significant regression of RNFL thickness. Advanced Analysis tools allow the user to override the retinal segmentation algorithm. The resulting retinal segmentation is used for calculation and analysis. Presentation title XXX Page 25 Version xx/200y 1.1 Glaucoma Solutions FF450plus – Fundus camera with VISUPAC® Provides the highest optical resolution available, and it is the only fundus camera with telecentric optics that guarantee precise retinal measurements. Increased number of flash settings and an ergonomically designed instrument table. FF450Plus uses the popular Leica R-8 35mm body. Integrates seamlessly with the VISUPAC Digital Imaging System. - Multiple image overlay, merge and graphic functions. - DICOM conformant and reading center approved. Presentation title XXX Page 26 Version xx/200y 1.1 Glaucoma Solutions VISUCAM NM/FA – Fundus camera with VISUPAC® High-resolution fluorescein angiography and brilliant color photos. External and internal LED fixation targets plus ZEISS AutoMap enables an automatic wide overview of the retina. Small pupil mode for color exposures enables photos with pupil diameters of just 3.3 mm. Compact, ergonomic all-in-one system – Photograph and evaluate retinal photography on the same device while being able to send images through any existing network. Presentation title XXX Page 27 Version xx/200y 1.1 Retina Solutions Optical Coherence Tomography Cirrus™ HD-OCT Stratus OCT™ Fundus Cameras FF450plus with VISUPAC® VISUCAM NM/FA VISUCAM PRO NM Ophthalmic Lasers VISULAS 532S VISULAS 690S VISULAS 690plus Slit Lamps SL 115 SL 120 SL 130 Presentation title XXX Surgical Microscopes OPMI Lumera® OPMI Lumera® T Invertertube™ Digital Visualization Page 28 Version xx/200y 1.1 Retina Solutions Optical Coherence Tomography Cirrus™ HD-OCT - High definition spectral domain imaging Stratus OCT™ – Comprehensive glaucoma and retinal imaging and analysis Fundus Cameras FF450plus with VISUPAC® - Multiple image overlay, merge and graphic functions provide a broad range of tools. VISUCAM NM/FA / VISUCAM PRO NM - Fundus cameras that can photograph through undilated pupils as small as 3.3mm Slit Lamps SL 115 – Superb optics for diagnosis, routine examinations and contact lens fitting. SL 120 – Ultimate in performance for diagnosis and documentation. SL 130 – For the full spectrum from diagnosis to therapy. Presentation title XXX Page 29 Version xx/200y 1.1 Retina Solutions Cirrus™ HD-OCT – High definition spectral domain imaging Exquisite high definition images and optimized workflow. Advanced optics enable examination of patients even with cataracts or pupils as small as 2.5mm. Mouse Driven Alignment™ provides image capture and analysis in just a few clicks. Real-Time Registration™ assures precise visit-to-visit registration and excellent reproducibility. Presentation title XXX Page 30 Version xx/200y 1.1 Retina Solutions STRATUS OCT™ – Optical coherence tomography V 5.0 Clinically proven diagnostic insight across a broad spectrum of ophthalmic conditions. Guided Progression Analysis™ (GPA) – Plots a linear regression analysis of average RNFL thickness data and reports statistically significant regression of RNFL thickness. Advanced Analysis tools allow the user to override the retinal segmentation algorithm. The resulting retinal segmentation is used for calculation and analysis. Presentation title XXX Page 31 Version xx/200y 1.1 Retina Solutions FF450plus – Fundus camera with VISUPAC® Provides the highest optical resolution available, and it is the only fundus camera with telecentric optics that guarantee precise retinal measurements. Increased number of flash settings and an ergonomically designed instrument table. FF450plus uses the popular Leica R-8 35mm body. Integrates seamlessly with the VISUPAC Digital Imaging System. - Multiple image overlay, merge and graphic functions. - DICOM conformant and reading center approved. Presentation title XXX Page 32 Version xx/200y 1.1 Retina Solutions VISUCAM NM/FA – Fundus camera with VISUPAC® High-resolution fluorescein angiography and brilliant color photos. External and internal LED fixation targets plus ZEISS AutoMap enables an automatic wide overview of the retina. Small pupil mode for color exposures enables photos with pupil diameters of just 3.3 mm. Compact, ergonomic all-in-one system – Photograph and evaluate retinal photography on the same device while being able to send images through any existing network. Presentation title XXX Page 33 Version xx/200y 1.1 Connectivity Presentation title XXX Page 34 Version xx/200y 1.1 Connectivity Solutions Network and communication standards (e.g., DICOM) User interface standards Digital documentation and databases (e.g., VISUPAC®) Connectivity to expert systems Presentation title XXX Page 35 Version xx/200y 1.1 Connectivity Solutions We develop new ways to connect our instruments and systems VISUPAC® Review Stations VISUCAM PRO NM VISUCAM NM /FA FF450plus DICOM Connection Stratus OCTTM Visante® OCT HFATM II IOLMaster® Print2VISUPAC Server and VISUPAC databace DICOM Interface Storage HFA II GDxTM ATLAS® Corneal Topographer EMR Interface Classic Connection Picture Archive System (PACS) Presentation title XXX Electronic Medical Record System EMR Page 36 Version xx/200y 1.1 On-Going Business Support Services Practice-building programs Reimbursement support Investment analyzers Presentation title XXX Page 37 Version xx/200y 1.1 Customer Care Going beyond traditional service, Carl Zeiss Meditec wants to partner with you, our customers, to create a positive, lifelong customer care experience. We want to earn your loyalty by delivering services that anticipate your needs. Presentation title XXX Page 38 Version xx/200y 1.1 Our Services and Support Triage problems for quick solutions Provide direct contact to Technical Support Engineers whenever necessary Dispatch Field Support Engineers who provide on-site support Refer instrument practice management issues to Regional Sales Managers for assistance Email responses to questions posted on our web site Telephone contact upon request from Customer Service Offer On-line Knowledge Base and answers to FAQs Provide technical training Distribute updated service manuals, guides and bulletins Presentation title XXX Page 39 Version xx/200y 1.1 Clinical Support In depth, on-site product and applications training Additional education and training updates Continuing education for clinic service technician certificate support Availability of Clinical Applications Support Specialist Presentation title XXX Page 40 Version xx/200y 1.1 A Partner You Can Count On 160 years of innovation and leadership Products with unmatched quality and performance A comprehensive distribution network Unparalleled training, service, and support An unwavering commitment to your success Presentation title XXX Page 41 Version xx/200y 1.1