FUNGAL SKIN INFECTIONS Liz McKensey Presentation 24yr old male Recent holiday in Spain Painful, scaling, flaking, itchy lesions on feet Between fourth and fifth digits Thinks his friend has a similar problem Diagnosis Pompholyx-type eczema b. Tinea pedis c. Cellulitis d. Eczema a. Diagnosis Pompholyx-type eczema b. Tinea pedis c. Cellulitis d. Eczema a. Treatment options Advise on general hygiene and avoid occlusive footwear + Itraconazole 100mg od po for 1-2 months b. Terbinafine (topical) tds for 1-2 weeks c. Terbinafine 250mg od po for 1-2 months d. Clotrimazole (topical) tds for 1-2 weeks a. Treatment options Advise on general hygiene and avoid occlusive footwear + a. Itraconazole 100mg od po for 1-2 months b. Terbinafine (topical) tds for 1-2 weeks c. Terbinafine 250mg od po for 1-2 months d. Clotrimazole (topical) tds for 1-2 weeks Presentation 37 year old female Type I DM Pain and infection of the right foot First started 3 to 4 days ago Initially blisters + weeping between toes of the right foot only Recently bought a second-hand pair of tennis shoes at a garage sale and has been wearing the shoes without socks Treatment Phenoxymethylpenicillin 500mg qds po + flucloxacillin 500mg qds po for 1 week b. Itraconazole 100mg od po for 1-2 months c. Phenoxymethylpenicillin 500mg qds po + flucloxacillin 500mg qds po for 1-2 weeks + antifungal treatment d. Hospital admission for IV antibiotics a. Treatment Phenoxymethylpenicillin 500mg qds po + flucloxacillin 500mg qds po for 1 week b. Itraconazole 100mg od po for 1-2 months c. Phenoxymethylpenicillin 500mg qds po + flucloxacillin 500mg qds po for 1-2 weeks + antifungal treatment d. Hospital admission for IV antibiotics a. Presentation 44yr old female Works as beauty therapist Asymmetrical whitening + yellow/black discolouration of the nails Also some changes of fingernails but toenails worse Diagnosis a. Psoriasis b. Senile ischaemia c. Onychomycosis d. Eczematous eruptions (contact dermatitis) Diagnosis a. Psoriasis b. Senile ischaemia c. Onychomycosis d. Eczematous eruptions (contact dermatitis) Treatment Topical amorolfine for 3 months b. Itraconazole 200mg bd po for 1 week per month for 3-6 months or Terbinafine 250mg od po for 3-6 months c. Topical + oral d. No treatment a. Treatment Topical amorolfine for 3 months b. Itraconazole 200mg bd po for 1 week per month for 3-6 months or Terbinafine 250mg od po for 3-6 months c. Topical + oral d. No treatment a. Psoriasis Contact dermatitis Presentation 16yr old male Slightly itchy asymmetrical scaly patches on the torso sparing the face, hands, feet, and groin Started in the axilla Concerned he has ‘caught something’ from his new girlfriend Diagnosis a. Psoriasis b. Pityriasis rosea c. Tinea versicolor d. Tinea corporis Diagnosis a. Psoriasis b. Pityriasis rosea c. Tinea versicolor d. Tinea corporis Treatment Clotrimazole 1% tds top for 1-2 weeks b. Terbinafine 1% bd top for 1-2 weeks c. Compound benzoic acid ointment tds top for 1-2 weeks d. Any of the above a. Treatment Clotrimazole 1% tds top for 1-2 weeks b. Terbinafine 1% bd top for 1-2 weeks c. Compound benzoic acid ointment tds top for 1-2 weeks d. Any of the above a. Note: Extensive skin infections may require oral therapies e.g.terbinafine 250mg daily for four week or itraconazole 100mg daily for 15 days Psoriasis Pityriasis Rosea Presentation 8yr old Afro-Carribean male Presents with scaly patches on scalp Started two weeks ago, but mum worried now because ‘his hair is falling out’ Two close friends off school for the last few days with similar problem Diagnosis a. Kerion b. Tinea capitis c. Folliculitis decalvans d. Bacterial pyodermas Diagnosis a. Kerion b. Tinea capitis c. Folliculitis decalvans d. Bacterial pyodermas Treatment Clotrimazole 1% tds top for 4 weeks b. Itraconazole 100mg od po for 4 weeks c. Griseofulvin 1g od po (15-20mg/kg for kids) d. Itraconazole 100mg od po for 4 weeks + clotrimazole 1% tds top for 1 week a. Treatment Clotrimazole 1% tds top for 4 weeks b. Itraconazole 100mg od po for 4 weeks c. Griseofulvin 1g od po (15-20mg/kg for kids) d. Itraconazole 100mg od po for 4 weeks + clotrimazole 1% tds top for 1 week a. True or false Tinea capitis can lead to scarring alopecia (and permanent hair loss) Tinea capitis requires systemic antifungal treatment for therapeutic success Tinea capitis is very infectious so that children may have to be kept away from school If tinea capitis is suspected clinically then it is important to confirm or refute this diagnosis by further investigation (e.g. taking skin scrapings and hair for fungal elements) Asymptomatic carriers should be treated with topical antifungals alone Presentation The previous boys classmate Diagnosis a. Abscess (staph aureus) b. Cellulitis c. Kerion d. Pustular dermatosis Diagnosis a. Abscess (staph aureus) b. Cellulitis c. Kerion d. Pustular dermatosis Treatment Griseofulvin 1g od po for 8 weeks b. Griseofulvin + prednisolone c. Griseofulvin + prednisolone + flucloxacillin d. Surgery a. Treatment Griseofulvin 1g od po for 8 weeks b. Griseofulvin + prednisolone c. Griseofulvin + prednisolone + flucloxacillin d. Surgery a. Presentation 22yr old male Concerned he has Michael Jackson’s disease!! Reports that he has been quite itchy all over On examination he has multiple well-demarcated, scaly, oval- to-round hypopigmented macules occasionally forming into larger patches Mostly on upper trunk and arms, some areas on neck also States he usually has a good tan and admits to often using tanning oils when away on holidays Diagnosis a. Postinflammatory pigmentary change b. Pityriasis rosea c. Tinea versicolor d. Vitiligo Diagnosis a. Postinflammatory pigmentary change b. Pityriasis rosea c. Tinea versicolor d. Vitiligo Treatment Clotrimazole cream 1% top tds for 7 days b. Ketoconazole shampoo od used as body wash for 7 days c. Itraconazole 100mg od po for 2 weeks d. All of the above a. Treatment Clotrimazole cream 1% top tds for 7 days b. Ketoconazole shampoo od used as body wash for 7 days c. Itraconazole 100mg od po for 2 weeks d. All of the above a. Vitiligo Presentation 32yr old male 135kg Describes a brownish red rash with ‘pimples’ around the border on the inside of his thighs/groin ‘Feels like it is burning and incredibly itchy at times’ Reports nothing on penis or scrotum Also reports itchy flaky skin between toes Diagnosis Candida intertrigo b. Contact dermatitis c. Tinea cruris d. Psoriasis a. Diagnosis Candida intertrigo b. Contact dermatitis c. Tinea cruris d. Psoriasis a. Treatment Clotrimazole cream 1% top tds for 7 days b. Clotrimazole 1% + hydrocortisone 1% (cream) top tds for 7 days c. Clotrimazole cream 1% top tds + itraconazole 100mg od po for 7 days d. Any of the above a. Treatment Clotrimazole cream 1% top tds for 7 days b. Clotrimazole 1% + hydrocortisone 1% (cream) top tds for 7 days c. Clotrimazole cream 1% top tds + itraconazole 100mg od po for 7 days d. Any of the above a. Candida Intertrigo