Reaxys Demonstration Search Chemistry 137 – Spring 2013 Grace Baysinger Head Librarian & Bibliographer, Swain Chemistry & Chemical Engineering Library graceb@stanford.edu Reaxys – Home Page There are three tabs for searching. Chose Substances and Properties. Reaxys – Generate Structure from Name Click on Generate structure from name button. Then enter name in popup box. Reaxys – Found Chemical Structures If more than one structure is retrieved, choose one that best matches your needs. Reaxys – Substructure Search of Vancomycin Do substructure search, include tautomers and ignore stereo Reaxys – Initial Search Results Filters for refining search results Summary of available information for each structure Reaxys – Filter by Bioactivity – Limit to Substances with Pharmacological Data There are 3,747 articles/patents that have bioactivity on Vancomycin Reaxys – Limit to Articles/Patents Published in 2009-2010 Reaxys – Citations Display Form for Reviewing Results View results in Citations format to see titles of articles of potential interest Reaxys – Output Results Click on Output choice to create PDF of search results Reaxys – Popup Window Choices for Specifying Output Format Reaxys – Output Citation Results Reaxys – Record from Output that includes Hit Substance, Citation, and Abstract for Reference with Bioactivity Information View in Reaxys hot link lets you go to substance record for that compound from PDF Reaxys – Online Training at http://info.reaxys.com Training center includes Quick Reference Guide