Reaxys
‘The new web based workflow solution
for Chemical Scientists’
Dr. Denis Reidy, Product Sales Manager
Agenda
• What is Reaxys?
• What is the content and the primary source of information?
• Who is it for?
• What are the values for different types of users?
• Competitive analysis
• Customer feedback
2
Chemistry R&D in Turkey
 Chemistry, Engineering and Medical Specialities the top 3 main
R&D areas in Turkey
 Chemistry illustrates the most inter-disciplinary strengths
 70% of the articles related to No. 1 distinctive competencies in
Turkish universities are from the field of chemistry
 5.85% article increase across all disciplines in Turkey in 2010,
6th in growth globally
Turkey values chemistry and desires increased visibility
What is Reaxys?
What is Reaxys?
 Elsevier’s premier workflow tool for research chemists &
related science
 An extensive repository of chemical properties and reaction
data presented with chemistry as the organizing principle
 A resource for accurate and validated experimental data. High
quality answers you can use with confidence.
 A simple interface, easy to work with. Analysis and planning
tools offer new, and fast functions that help identify and plan
the synthesis of molecules.
 A web-based product that makes chemistry research more
efficient, and helps to achieve better results. Simply access at
www.reaxys.com
J. Org. Chem.
What is Reaxys?
J. Med. Chem.
J. Am. Chem. Soc.
• Chemistry
• ~200 years of organic, organometallic and inorganic
chemistry
• Experimentally validated structural, chemical, and
physical data from Journal articles and patents
• Based on the 3 CrossFire Databases.
• Intuitive
• Easy to use, appealing web-interface, available anytime
and anywhere without limits and without installation
needs
• Allowing chemists to query and filter by property data,
design the optimum synthesis route, and view multistep reactions.
• Created from scientist for scientist
• Workflow Solution
• Supporting scientists in life science and chemistry in
industry and academia in their daily work
• Providing decision support in finding relevant and
validated chemical information
• Helping to reduce time and efforts in building synthesis
plans
Heterocycles
Applied Spectroscopy
J. Of Mass Spectrometry
Biomolecular Spectroscopy
Biochemical Pharmacology
Bioorganic and Med.
Chemistry
Chem. of Natural
Compounds
Experimental Physiology
What do chemists
want to know?
1. What is this?
•
•
Is it novel? Patented?
What are its physical characteristics
(weight, melting point, etc?)
2. What does it do?
•
•
•
Is it a reagent? Solvent?
What is its bioactivity?
Pharmacology?
Is it toxic?
3. How can I make it?
•
•
How can I change it?
How can I make it better?
Where would you need Reaxys a customer’s question to the world
TO: CHMINF-L@listserv.indiana.edu
SUBJECT: [CHMINF-L] Looking for Information
My patron is looking for a prep of CAS RN 1603-02-7 which is 4-pyrmidinol, 2,5,6-triamino- 4(hydrogen sulfate).
The ‘standard’ old method of finding answers –
dig through the literature
TO: CHMINF-L@listserv.indiana.edu
SUBJECT: [CHMINF-L] Looking for Information
One of our searchers at
information relevant to
Two citations – no data
found these two references through
query:
. These may provide
Bisheterocyclic synthesis and antimicrobial studies on some biologically significant 2-[N-(3'chloro-4'-substituted azetidinone-2)]amino-6-hydroxypurines.
Sharma, Pratibha; Kumar,
Ashok; Sharma, Shikha. School of Chemical Sciences, Devi Ahilya University, Indore, India.
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry
(2004), 43B(2), 385-388. Publisher: National Institute of Science Communication, CODEN:
IJSBDB ISSN: 0376-4699.
Journal written in English.
Synthesis of guanine.
Chen, Xin; Wang, Ying. China Pharm. Univ., Nanjing, Peop. Rep.
China. Zhongguo Yiyao Gongye Zazhi (1992), 23(1), 32-3. CODEN: ZYGZEA Journal written
in
Chinese. Message---------Original
Does not answer the researchers’
question.
From:
xxxxxx
CHMINF-L@listserv.indiana.edu
Researcher needs to know how, notTo:where
or if.
My patron is looking for a prep of CAS RN 1603-02-7 which is 4-pyrmidinol, 2,5,6-triamino- 4(hydrogen sulfate).
Reaxys extracts valuable chemical properties
and reaction details from journals and patents...
1H
NMR
300
MHZ
......And gives you what no other database has.....
• > 29 million Reactions
(how things are made)
• Properties for
> 19 million Substances
Hundreds of searchable fields
Interoperability with Scopus and Science Direct
for a full solution for researchers
Reaxys provides explicit answers
• What chemistry is known about a certain research topic/effect?
• Which compounds have a certain physicochemical property?
• Which compounds show certain biological effects?
• Does a compound exist and if so what is known about it?
• Is it toxic?
• What are its physical characteristics (melting point, solubility, etc?)
• Any biological effects known?
• How can I get a given compound?
•
•
•
•
Can I make it and if so how?
Can I buy it?
Can I make something like it?
Can I make it better?
Melting Point
Solubility
Pharm.Effect
Who is Reaxys for?
Who is Reaxys for?
• Reaxys supports the discovery process in synthetic chemistry and related
disciplines
Medicinal chemists
Synthesis chemists
Information Specialists
Process engineers
Chemical engineers
How does Reaxys answer the researcher’s
question?
With one simple query, Reaxys gives them an exact answer with detailed
experimental data and references for the full-text article if needed.
"...advantage is that
the reaction data is
already extracted
from the journal
article citations,
whereas SciFinder
will provide you
with a list of
references which
you then must
order and read“
subject librarian
from US
Unique tools that save researchers days of
reading
• Create full synthesis plans
with all experimental details
• Each step can come from a different
publication
• Complex problems
normally requiring
weeks of research can
be done in minutes
“What you just showed
would have taken me
a week to do”
Dr Andy Liepa, CSIRO
Chief Research Scientist and
namesake of Liepa
phenanthrenes synthesis
Five good reasons to use Reaxys
1. The wealth of experimentally validated data
which can be searched, filtered and ranked to
find the most relevant answer to a specific
question quickly.
2. Functionality beyond data searching: synthesis
planner, results management, smart analysis
tools for fast evaluation.
3. No user or usage limits: flat-rate for
institution-wide access at any time.
4. The intuitive interface and online educational
material help reduce your training efforts.
5. Interoperable: linking to SciVerse Scopus, fulltexts at publishers and patent offices. Access to
your own library settings via OpenURL resolver
is possible.
Professor Peter Johnson, University of Leeds
Competitive Analysis:
Reaxys is built for chemists’ workflow
Reaxys
Other chemistry databases


Tools and features deliver actionable
outcome




Reactions generated across articles
and patents

Workflow driven, refineable searches,
easy-to-use

Exporting capabilities: RD/SD files,
Excel, pdf
Often just give links to articles
that then must be read
Difficult to navigate across the
various results and databases
User interfaces not intuitive,
steep learning curves
Limited exporting
A comparison (done by a customer)
Bibliographic Result (what the customer reported):
Reaxys:
4 Patents
SciFinder: 6 Patents
2 of the 4 that Reaxys found did not come up in SciFinder
The value of a Result is not equal to the Number of Patents
in the Database, but to the quality of the indexing.
However, the value of SciFinder is equal to the number of
Patents found with a search.
Conclusion: Always look behind the numbers
Factual Result:
Reaxys:
20 Reactions (5 out of Patents, including an experimental procedure from 1988)
SciFinder: No Reaction
This is what we always need to ask for: which results did the search give,
besides a bunch of Patents to read?
Conclusion: After comparing to the SciFinder strength, check what does SF has against Reaxys’ strength!
How does Reaxys rate with top research?
10 of the Global Top-10
24 of the Global Top-25
87 of the Global Top-100
- 2010 Global Chemistry Rankings
Reaxys Value Story
“ I can get my work done 3 times faster since I have begun
searching Reaxys. Life has certainly become easier. The
interface really enables me to find the content I need and to get it
out. I find that it’s more difficult to extract data from SciFinder. ”
“ It’s a very straightforward way to obtain and sift through a
huge amount of information from over the last 150 years.”
“ I really like the simplicity of the user interface. I don’t have to
read manuals to get answers fast. ”
“ The flat rate access is important for every moderate to large
institution. Now we have access for a sufficient number of
simultaneous users. ”
Peter Johnson, PhD, University of Leeds
Research Professor, School of Chemistry
But don‘t just listen to us, listen to our
customers
“It is obvious that Reaxys has
"After almost one year of searching
and using Reaxys, my users and I just
love it."
been programmed with the needs
and expectations of chemists in
mind”
Norah Xiao, Science Librarian, University of Southern
California
Prof. Ulrich Jordis, Vienna University of
Technology, Austria
“Reaxys is a joy to use… It’s beautiful.”
US Librarian
"The patent information is great."
Professor Anthony Barrett, Imperial College London
“Whenever we hit stumbling blocks,
Reaxys helps drive the critical
decisions.”
Group Leader, Acoris
“Reaxys thinks and works like
chemists do. So it’s easy for
most chemists to find the
information they need.”
Tommi Meulemanns, Mercachem
"A chemist without access to Reaxys is like a
computer without a monitor. It's able to work,
but is blind" Vladimir Maslenko, Senior Researcher, Organic
Chemistry: Mendeleyev University of Chemical Technology
Any Questions about Reaxys ……
• ... And if you have any questions about Reaxys or search strategies,
please contact us:
26
Thank you
www.info.reaxys.com
www.reaxys.com
Dr. Denis Reidy
d.reidy@elsevier.com
+31 610 680990
Maximising the Chemistry
Research Workflow