September 30 – October 3, 2013
Westin Harbour Castle Hotel
Toronto, Canada
Denis Grant (Chair)
Univ of Toronto ON
Stelvio Bandiera
UBC, Vancouver BC
Jack Bend
UWO, London ON
Chantal Guillemette
Laval Univ, Quebec PQ
Malle Jurima-Romet
Celerion, Montreal PQ
Roger Keefe
Imperial Oil, Calgary AB
David K. Lee
NoAb, Mississauga, ON
Tom Massey
Queen’s Univ, Kingston ON
Eddie Morgan
Emory Univ, Atlanta GA
Sandy Pang
Univ of Toronto, Toronto ON
Allan Rettie
Univ of Washington, Seattle WA
David Riddick
Univ of Toronto, Toronto ON
Nathalie Rioux
Boehringer Ingelheim, Laval PQ
Rachel Tyndale
Univ of Toronto, Toronto ON
Jack Uetrecht
Univ of Toronto. Toronto ON
Peter Wells
Univ of Toronto, Toronto ON
Ann Daly
– Newcastle University, UK
Patrick Dansette
- Université Paris, France
Xinxin Ding
– Wadsworth, Albany NY, USA
Uwe Fuhr
– University Hospital of Cologne, Germany
Ron Hines
– Medical College of Wisconsin, Milwaukee WI, USA
Paul Hollenberg
– University of Michigan, Ann Arbor MI, USA
Magnus Ingelman-Sundberg
– Karolinska Instutute, Stockholm, Sweden
Tetsuya Kamataki
– Inst for Genome Function, Fujisawa, Japan
Richard Kim
– Univ of Western Ontario, London, ON, Canada
Steve Leeder
– Children's Mercy Hospital, Kansas City MO, USA
Peter Mackenzie
– Flinders University, Adelaide, Australia
Larry Marnett
– Vanderbilt Univ, Nashville TN, USA
Urs Meyer
– Biozentrum, Univ of Basel, Basel, Switzerland
Franz Oesch
– Univ of Mainz, Mainz, Germany
B. Kevin Park
- University of Liverpool, Liverpool, UK
Olavi Pelkonen
- University of Oulu, Oulu, Finland
Lance Pohl
- NIH/NHLBI, Bethesda, Maryland, USA
Rory Remmel
- University of Minnesota, Minneapolis, Minnesota, USA
Glenn Sipes
- University of Arizona, Tucson, Arizona, USA
Bill Smith (President-Elect)
- Pfizer Inc La Jolla Labs, San Diego, California, USA
Steve Tannenbaum
- MIT, Cambridge, Massachusetts, USA
Ken Thummel
- University of Washington, Washington, USA
Jacques Turgeon
- Universite de Montreal, Montreal PQ, Canada
Mike Waterman
- Vanderbilt University, Nashville, Tennessee, USA
David Waxman
- Boston University, Boston, Massachusetts, USA
Yasushi Yamazoe
- Tohoku University, Sendai, Japan
Uli Zanger
- Dr. Margarete Fischer-Bosch Institute, Stuttgart, Germany
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4-6 Short Courses
3 Keynote Lectures
2 Plenary Sessions
ISSX Awards and Award Lecture
8-12 Symposia
4-6 Industry-Sponsored Luncheon Seminars
3 Days of Poster Viewing
1 Poster Awards Session
3 Days of Commercial Exhibits
½ Day Free Time
Welcome Reception
ISSX Banquet
Sunday, September 29, 2013
12:00 - 18:00
Staff Prep
Monday, September 30, 2013
08:00 - 19:00
10:00 - 3:00 PM
Registration Open ISSX Council Meeting
09:00 - 12:00
12:00 - 14:00
14:00 - 17:00
18:00 - 18:15
18:15 – 19:00
19:00 – 21:00
Short Course I
Short Course II
Short Course III
Lunch for Short
Course Attendees
Short Course IV
Short Course V
Short Course VI
Opening Welcome
Address
Keynote Lecture 1
Welcome Reception
Tuesday, October 1, 2013
08:00 - 17:00
09:00 – 11:00
11:00 – 11:30
11:30 – 12:30
12:30 – 14:00
14:00 – 16:00
16:00 – 16:30
16:30 – 18:30
Registration Open
Plenary Session 1
Refreshment Break
ISSX Awards and
Award Lecture
Lunch
Industry Seminars
Poster Viewing
Exhibits
Symposium 1
Symposium 2
Symposium 3
Refreshment Break
Poster Viewing
Symposium 4
Symposium 5
Symposium 6
11:00 – 11:30
11:30 - 12:30
12:30 - 14:00
14:00 – 19:00
19:00 - 22:00
Refreshment Break
Keynote Lecture 2
Lunch
Industry Seminars
Poster Viewing
Exhibits
Free Afternoon
ISSX Banquet
Wednesday, October 2, 2013
08:00 - 17:00
Registration Open
09:00 – 11:00
Plenary Session 2
Thursday, October 3, 2013
08:00 - 17:00
09:00 - 11:00
11:00 – 11:30
11:30 - 12:30
12:30 – 14:00
14:00 - 16:00
16:00 – 16:30
16:30
Registration Open
Symposium 7
Symposium 8
Refreshment Break
Keynote Lecture 3
Lunch
Industry Seminars
Poster Viewing
Exhibits
Symposium 9
Symposium 10
Poster Awards
Closing
Preliminary topics:
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Role of inflammation in chemical carcinogenesis
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Development and uses of stem cell derived hepatocyte-like cells and cultured
transformed cells
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Utility and challenges of genome-wide association studies in pharmacogenetics
research
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Extrapolation from in vitro and cell-based systems to predict in vivo human drug
metabolism
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Extrapolation of animal drug disposition studies to humans
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Utility of genetically modified animals in human drug disposition studies
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Toxicogenomic profiling: current status and future utility in drug development
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Drug-metabolizing enzymes as therapeutic targets
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Receptor cross-talk in the regulation of drug metabolizing enzyme expression
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Metabolomic profiling as a tool for identifying novel drug target interactions
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Role of oxidative stress in cell physiology and pathology
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Pharmacogenomics and translational medicine: promise and challenge
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Effect of natural products on drug disposition
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Methods for prediction of drug-drug interactions
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Systems biology and xenobiotic-host interactions: concepts and technologies
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Impact of advanced genome sequencing technologies on personalized medicine
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Neuronal damage and neuroprotection against chemical insult
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DNA damage and repair mechanisms in cancer risk
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Cell type specific cytotoxic mechanisms
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New approaches to the development of biomarkers for drug-induced toxicity
Members:
500
Non-members:
200
Students:
300
TOTAL
1000
• Oct 2011– May 2012
(24-16 mo)
• MOC/SAB memberships approved and finalized (1 mo)
• MOC/SAB meetings/teleconferences/email circulars –
scientific program details finalized (7 mo)
• May 2012
(16 mo)
• Finalized program, speakers and titles sent to SAC
• SAC approval of program
• June – Oct 2012
(16-12 mo)
• Speaker invitations
• Identification/approval of satellite meetings
Shopping
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Bloor Street
Yorkville
St. Lawrence Market
Eaton Centre
Distillery District
Neighbourhoods
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Arts & Culture
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Art Gallery of Ontario
Royal Ontario Museum
Toronto Symphony
Live Theatre
Opera
Sports: MLB Playoffs?!
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Chinatown
Kensington Market
The Beaches
Little Italy
Queen Street West
Danforth/Greektown
Leaside
Roncesvalles Village
Bloor West Village
Walking/Cycling
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Harbourfront
Discovery Walk tours
‘City of Ravines’
September 30 – October 3, 2013
Westin Harbour Castle Hotel
Toronto, Canada