Name: ________________________
Gr. 12
Date_______________________
Biology worksheet -Cell communication
1st Semester, School Year 2023-2024
.
Multiple Choice
Identify the choice that best completes the statement or answers the question.
Use the diagram below to answer the
following 2 questions
a.
The channel receptor with a closed gate
waiting for the signaling molecule to bind
to the receptor
b. The dissociation of the receptor from the
receptor protein, allowing the gate to
close and prohibiting ions from entering
c. The signaling molecule binding to the
receptor, allowing the gate to open for
ions to flow through the channel
d. A hormone passing through the plasma
membrane via a G protein-coupled
receptor
2.
Which type of membrane receptor (B) is
represented in the diagram?
a. Receptor Tyrosine Kinase
b. Ligand-Gated Ion Channel Receptor
c. G Protein-Coupled Receptor
d. Phosphorylation Cascade
1. What is Part 2 of the diagram showing?
1
3. Yeast and mammals share very similar cell
communication molecules and pathways.
What does this suggest about yeast and
mammals?
a. Yeast and mammals share a recent
common ancestor
b. Early versions of cell communication
mechanisms still used today must have
evolved before the first multicellular
organisms
c. Signaling molecules first evolved in
multicellular eukaryotes
d. All cell communication systems are used
for sexual reproduction
4. Which of the following signaling
mechanisms represent a correctly matched
pair?
5. Identify the correct sequence of cell
signaling.
a. Activation of cellular response,
Reception, Transduction
b. Transduction, Reception, Activation of
cellular response
c. Reception, Transduction, Activation of
cellular response
d. Reception, Activation of cellular
response, Transduction
6. During which process do cells enter into
programmed cell death, during which time
DNA is chopped up, organelles are
fragmented, the cell shrinks and parts of the
cell are packaged into vesicle and removed by
scavenger cells?
a. Apoptosis
b. Catastrophism
c. Cytokinesis
d. Endocytosis
a. endocrine- neural communication
b. synaptic- intravenous communication
c. paracrine- communication with nearby,
surrounding cells
d. gap junction- communication via
hormones
2
Short Answer
Model 1 — Types of Signaling
3. Which of the cellular communication
methods in Model 1 appear to be for
signaling between cells in different parts of
an organism (long-distance communication)?
4. In which of the cellular communication
methods would a ligand (signaling molecule)
need to have the longest "life"? Explain your
reasoning.
5. Cellular communication takes place for a
variety of reasons—mating, defense
mechanisms, homeostasis, growth, etc.
Discuss the following question
1. Label the diagrams in Model 1 with the type
of cellular communication methods.
"Do all ligands for cellular communication
have the same chemical structure (shape)?"
Provide specific reasons or examples to
support your prediction.
2. Which of the cellular communication
methods in Model 1 appear to be for
signaling between cells that are in close
proximity?
3
Consider each of the following cellular
communication examples. Determine
which type of signaling is being used in
their scenario, and then present their
reasoning
9. Cells in the pituitary gland produces thyroid
stimulating hormone (TSH), which is
received by cells in the thyroid. The arrival of
TSH in the thyroid triggers the production of
several hor¬mones, which then travel
throughout the body to regulate metabolism.
6. Pheromones released by a female gamete cell
(egg) provide a pathway for the male gamete
cell (sperm) to travel, increasing the
possibility of fertilization.
7. Some cancer cells release their own growth
hormone rather than relying on growth
hormones from the host organism or from
other cells. This presents challenges to cancer
researchers looking for ways to slow the
growth of cancer cells.
8. Neurotransmitters are ligands that are
released from the axon of one nerve cell to
the dendrite of another nerve cell. This helps
to propagate the signal across several cells.
4
ID: A
.
Answer Section
MULTIPLE CHOICE
1.
2.
3.
4.
5.
6.
C
B
B
C
C
A
SHORT ANSWER
1. A: Autocrine signaling
B: Direct signaling
C: Paracrine signaling
D :Endocrine signaling
2. Types B and C.
3. Type D
4. Type D, the molecule must travel long distances and therefore must be stable longer.
5. Answers may vary. Students should come to the conclusion that if all ligands were alike, then signals
could be misunderstood. Therefore, ligands for signaling different purposes must have different shapes
6. Endocrine—In the case of a human uterus, the pheromone would need to travel within the uterus to the
sperm, this is a fairly large distance compared to the size of a cell.
7. Autocrine—The signal is released from and received by the same cell.
8. Paracrine—The signal only travels a short distance from one cell to a neighboring cell.
9. Endocrine—The ligands (hormones) travel a fairly large distance throughout the body
1
Name: ________________________
Gr. 12
Date_______________________
Biology worksheet -Cell communication
1st Semester, School Year 2023-2024
.
Multiple Choice
Identify the choice that best completes the statement or answers the question.
1. Which of the following signaling
mechanisms represent a correctly matched
pair?
3. During which process do cells enter into
programmed cell death, during which time
DNA is chopped up, organelles are
fragmented, the cell shrinks and parts of the
cell are packaged into vesicle and removed by
scavenger cells?
a. Catastrophism
b. Apoptosis
c. Cytokinesis
d. Endocytosis
a. synaptic- intravenous communication
b. gap junction- communication via
hormones
c. paracrine- communication with nearby,
surrounding cells
d. endocrine- neural communication
2. Yeast and mammals share very similar cell
communication molecules and pathways.
What does this suggest about yeast and
mammals?
a. All cell communication systems are used
for sexual reproduction
b. Signaling molecules first evolved in
multicellular eukaryotes
c. Early versions of cell communication
mechanisms still used today must have
evolved before the first multicellular
organisms
d. Yeast and mammals share a recent
common ancestor
1
Use the diagram below to answer the
following 2 questions
5.
Which type of membrane receptor (B) is
represented in the diagram?
a. G Protein-Coupled Receptor
b. Receptor Tyrosine Kinase
c. Ligand-Gated Ion Channel Receptor
d. Phosphorylation Cascade
6. Identify the correct sequence of cell
signaling.
a. Transduction, Reception, Activation of
cellular response
b. Activation of cellular response,
Reception, Transduction
c. Reception, Transduction, Activation of
cellular response
d. Reception, Activation of cellular
response, Transduction
4. What is Part 2 of the diagram showing?
a. The dissociation of the receptor from the
receptor protein, allowing the gate to
close and prohibiting ions from entering
b. A hormone passing through the plasma
membrane via a G protein-coupled
receptor
c. The signaling molecule binding to the
receptor, allowing the gate to open for
ions to flow through the channel
d. The channel receptor with a closed gate
waiting for the signaling molecule to bind
to the receptor
2
Short Answer
Model 1 — Types of Signaling
3. Which of the cellular communication
methods in Model 1 appear to be for
signaling between cells in different parts of
an organism (long-distance communication)?
4. Label the diagrams in Model 1 with the type
of cellular communication methods.
Consider each of the following cellular
communication examples. Determine
which type of signaling is being used in
their scenario, and then present their
reasoning
1. Which of the cellular communication
methods in Model 1 appear to be for
signaling between cells that are in close
proximity?
5. Cells in the pituitary gland produces thyroid
stimulating hormone (TSH), which is
received by cells in the thyroid. The arrival of
TSH in the thyroid triggers the production of
several hor¬mones, which then travel
throughout the body to regulate metabolism.
2. In which of the cellular communication
methods would a ligand (signaling molecule)
need to have the longest "life"? Explain your
reasoning.
3
6. Some cancer cells release their own growth
hormone rather than relying on growth
hormones from the host organism or from
other cells. This presents challenges to cancer
researchers looking for ways to slow the
growth of cancer cells.
9. Cellular communication takes place for a
variety of reasons—mating, defense
mechanisms, homeostasis, growth, etc.
Discuss the following question
"Do all ligands for cellular communication
have the same chemical structure (shape)?"
Provide specific reasons or examples to
support your prediction.
7. Pheromones released by a female gamete cell
(egg) provide a pathway for the male gamete
cell (sperm) to travel, increasing the
possibility of fertilization.
8. Neurotransmitters are ligands that are
released from the axon of one nerve cell to
the dendrite of another nerve cell. This helps
to propagate the signal across several cells.
4
ID: B
.
Answer Section
MULTIPLE CHOICE
1.
2.
3.
4.
5.
6.
C
C
B
C
C
C
SHORT ANSWER
1. Types B and C.
2. Type D, the molecule must travel long distances and therefore must be stable longer.
3. Type D
4. A: Autocrine signaling
B: Direct signaling
C: Paracrine signaling
D :Endocrine signaling
5. Endocrine—The ligands (hormones) travel a fairly large distance throughout the body
6. Autocrine—The signal is released from and received by the same cell.
7. Endocrine—In the case of a human uterus, the pheromone would need to travel within the uterus to the
sperm, this is a fairly large distance compared to the size of a cell.
8. Paracrine—The signal only travels a short distance from one cell to a neighboring cell.
9. Answers may vary. Students should come to the conclusion that if all ligands were alike, then signals
could be misunderstood. Therefore, ligands for signaling different purposes must have different shapes
1
Name: ________________________
Gr. 12
Date_______________________
Biology worksheet -Cell communication
1st Semester, School Year 2023-2024
.
Multiple Choice
Identify the choice that best completes the statement or answers the question.
Use the diagram below to answer the
following 2 questions
1. Which of the following signaling
mechanisms represent a correctly matched
pair?
a.
gap junction- communication via
hormones
b. paracrine- communication with nearby,
surrounding cells
c. synaptic- intravenous communication
d. endocrine- neural communication
2.
Which type of membrane receptor (B) is
represented in the diagram?
a. Ligand-Gated Ion Channel Receptor
b. Receptor Tyrosine Kinase
c. Phosphorylation Cascade
d. G Protein-Coupled Receptor
1
3. What is Part 2 of the diagram showing?
a. The dissociation of the receptor from the
receptor protein, allowing the gate to
close and prohibiting ions from entering
b. A hormone passing through the plasma
membrane via a G protein-coupled
receptor
c. The signaling molecule binding to the
receptor, allowing the gate to open for
ions to flow through the channel
d. The channel receptor with a closed gate
waiting for the signaling molecule to bind
to the receptor
4. During which process do cells enter into
programmed cell death, during which time
DNA is chopped up, organelles are
fragmented, the cell shrinks and parts of the
cell are packaged into vesicle and removed by
scavenger cells?
a. Apoptosis
b. Catastrophism
c. Endocytosis
d. Cytokinesis
5. Yeast and mammals share very similar cell
communication molecules and pathways.
What does this suggest about yeast and
mammals?
a. All cell communication systems are used
for sexual reproduction
b. Early versions of cell communication
mechanisms still used today must have
evolved before the first multicellular
organisms
c. Signaling molecules first evolved in
multicellular eukaryotes
d. Yeast and mammals share a recent
common ancestor
6. Identify the correct sequence of cell
signaling.
a. Reception, Transduction, Activation of
cellular response
b. Reception, Activation of cellular
response, Transduction
c. Transduction, Reception, Activation of
cellular response
d. Activation of cellular response,
Reception, Transduction
2
Short Answer
Consider each of the following cellular
communication examples. Determine
which type of signaling is being used in
their scenario, and then present their
reasoning
4. Pheromones released by a female gamete cell
(egg) provide a pathway for the male gamete
cell (sperm) to travel, increasing the
possibility of fertilization.
1. Some cancer cells release their own growth
hormone rather than relying on growth
hormones from the host organism or from
other cells. This presents challenges to cancer
researchers looking for ways to slow the
growth of cancer cells.
2. Neurotransmitters are ligands that are
released from the axon of one nerve cell to
the dendrite of another nerve cell. This helps
to propagate the signal across several cells.
3. Cells in the pituitary gland produces thyroid
stimulating hormone (TSH), which is
received by cells in the thyroid. The arrival of
TSH in the thyroid triggers the production of
several hor¬mones, which then travel
throughout the body to regulate metabolism.
3
Model 1 — Types of Signaling
7. Label the diagrams in Model 1 with the type
of cellular communication methods.
8. Which of the cellular communication
methods in Model 1 appear to be for
signaling between cells that are in close
proximity?
9. Cellular communication takes place for a
variety of reasons—mating, defense
mechanisms, homeostasis, growth, etc.
Discuss the following question
5. In which of the cellular communication
methods would a ligand (signaling molecule)
need to have the longest "life"? Explain your
reasoning.
"Do all ligands for cellular communication
have the same chemical structure (shape)?"
Provide specific reasons or examples to
support your prediction.
6. Which of the cellular communication
methods in Model 1 appear to be for
signaling between cells in different parts of
an organism (long-distance communication)?
4
ID: C
.
Answer Section
MULTIPLE CHOICE
1.
2.
3.
4.
5.
6.
B
A
C
A
B
A
SHORT ANSWER
1.
2.
3.
4.
Autocrine—The signal is released from and received by the same cell.
Paracrine—The signal only travels a short distance from one cell to a neighboring cell.
Endocrine—The ligands (hormones) travel a fairly large distance throughout the body
Endocrine—In the case of a human uterus, the pheromone would need to travel within the uterus to the
sperm, this is a fairly large distance compared to the size of a cell.
5. Type D, the molecule must travel long distances and therefore must be stable longer.
6. Type D
7. A: Autocrine signaling
B: Direct signaling
C: Paracrine signaling
D :Endocrine signaling
8. Types B and C.
9. Answers may vary. Students should come to the conclusion that if all ligands were alike, then signals
could be misunderstood. Therefore, ligands for signaling different purposes must have different shapes
1