APBIO5 Mr. Nestojko Chapter 11 Questions There are three parts to

Mr. Nestojko
Chapter 11 Questions
There are three parts to this assignment, and each is designed to increase your
understanding and engagement with the material in Chapter 11 about cell
I. Book Questions
Please respond to:
p210 #1,2, and 4.
p214 #2.
P219 #1,2,3
P223 #1
P225 #1,2
MC pp226-227 #1-8
*remember, see appendix A for assistance on these
II. Knowledge/Comprehension Questions:
Respond to the following questions to ensure you have a working knowledge of
terminology in this chapter.
1. What are three stages of cell signaling?
2. What are the three stages of the signal transduction pathway?
3. What type of signaling is shown with a cell releasing a signal molecule into the
environment, followed by a number of cells in the immediate vicinity responding?
4. What is long distance signaling in the body called?
5. What is a ligand?
6. What activates a G protein?
7. What does a kinase enzyme do?
8. How does tyrosine kinase function in the membrane receptor?
9. What is dimerization?
10. How are ligand-gated ion channels similar to G protein-linked receptors and
receptor tyrosine kinases? How are they different?
11. How does testosterone in a cell illustrate how intracellular receptors work?
12. What are protein kinases?
Mr. Nestojko
13. What are protein phosphatases?
14. What is the difference between a first messenger and a second messenger?
15. What is cyclic AMP (cAMP) and what role does it play for the cell?
16. When cell signaling causes a response in the nucleus, what normally happens?
17. How do scaffolding proteins enhance a cellular response?
18. What is apoptosis?
19. What specifically happens during apoptosis?
20. What is a difference between cancer and apoptosis?
Write an essay response to the following prompt:
Cell receptors play an integral role in cellular communication.
A. Briefly list and describe the steps of a signal transduction cascade
B. Describe and discuss the mechanism by which a cell surface receptor sends a message
to the interior of the cell.
C. Describe and discuss the role of a receptor located in the cytosol with respect to
cellular communication.