1/20/2023 The Respiratory System Why do we breathe? Just Breathe! • We’re warm-blooded creatures who require OXYGEN to survive! • Function of the Respiratory System: provides oxygen FOR the body and allows carbon dioxide to leave the body • Works closely with the circulatory system to accomplish this gas exchange “When you can’t breathe, nothing else matters.” Canadian Lung Association 1 2 1 1/20/2023 The Respiratory System: • Respiration: Why do we need to breath oxygen? – all processes involved in the exchange of oxygen and carbon dioxide between cells & the environment O2 3 CO2 4 2 1/20/2023 The Respiratory System: Types of Respiration: • PRIMARY function: BREATHING (for gas exchange) – oxygen and carbon dioxide 1.) To get oxygen (O2) to its cells 2.) To get rid of excess carbon dioxide (CO2) O2 • Also used to produce SOUND 5 External Respiration • gas exchange with the surrounding air • (O2 and CO2 ) CO2 6 3 1/20/2023 Types of Respiration: HUMAN ADAPTATIONS • For efficient gas exchange to occur: Internal Respiration • gas exchange at the cellular level • (cellular respiration) 1. Water must be present at the respiratory surface. • glucose + oxygen → carbon dioxide + water + energy 7 Adaptation: Human lung located within the body cavity which contains a lot of water and air is moistened when it enters lungs. 8 4 1/20/2023 HUMAN ADAPTATIONS The Human Respiratory System 2. The respiratory surface must be large Adaptation: Massive surface area Larynx 9 Nasal Cavity Path taken by air Upper Path taken by food Respiratory Pharynx Tract Epiglottis Esophagus Trachea Bronchi Bronchioles Lower Respiratory Alveoli Tract Diaphragm 20 5 1/20/2023 External Respiration: Mechanics of Breathing 2 Phases: • Inspiration https://medlineplus.gov/ency/anatomyvideos/000018.htm – diaphragm contracts, volume increases, creating low pressure and drawing air in • Expiration – diaphragm relaxes, volume decreases, creating high pressure, forcing air out 23 24 6 1/20/2023 Mechanics of Breathing Breathing Movements • The body uses muscles to change the VOLUME of the thoracic cavity. • This alters the PRESSURE inside the lungs • An increase in volume = decrease in pressure (and vice versa) • Gas moves from an area of high pressure to an area of low pressure 25 26 7 1/20/2023 Respiratory Muscles • Diaphragm: dome shaped sheet of muscle separating thoracic and abdominal cavities. • Intercostal muscles: muscles of the ribcage – External intercostals: outer surface, pull ribs up – Internal intercostals: inner surface, pull ribs down 27 28 8 1/20/2023 Breathing Mechanics of INSPIRATION • Diaphragm CONTRACTS and FLATTENS (moves downwards) • Intercostals CONTRACT and move ribcage UPWARDS • Pleural membrane pulls on lungs • Result: – Lung volume: INCREASED – Pressure inside the lungs: DECREASED – AIR MOVES IN • Inspiration: the act of taking air INTO the lungs, occurs when pressure inside the lungs is LOWER than pressure outside the lungs (i.e. atmospheric pressure) • Expiration: the act of breathing OUT, occurs when pressure inside the lungs is GREATER than pressure outside the lungs (atmospheric) 29 30 9 1/20/2023 Mechanics of EXPIRATION • • • • Diaphragm RELAXES and RETURNS to DOME shape Intercostals RELAX and move ribcage DOWNWARDS Pleural Membrane no longer pulling on lungs Result: – Lung volume: DECREASED – Pressure inside the lungs: INCREASES – AIR MOVES OUT • *Internal intercostals can pull ribs in further to force exhalation 31 32 10 1/20/2023 Respiration and Gas Exchange • Once inside the lungs, air is exchanged with the gases in the bloodstream. • External Respiration: The exchange of O2 and CO2 between air and blood (occurs in the lungs). • The alveoli are surrounded by tiny blood vessels (capillaries); both have walls that are only a single cell layer thick to allow for diffusion of gases. 33 34 11 1/20/2023 Respiration and Gas Exchange Respiration and Gas Exchange • Once in the bloodstream, oxygen travels throughout the body. • the gases are exchanged due to differences in CONCENTRATION. – O2 in inhaled air > O2 in blood of capillaries in lungs. – CO2 in inhaled air < CO2 in blood of capillaries in lungs. • Internal Respiration: The exchange of O2 and CO2 between blood and the cells of the surrounding tissue (occurs in the body tissues). • So in external respiration, – O2 diffuses from the alveoli to the capillaries and – CO2 diffuses from the capillaries to the alveoli. 35 • As blood passes body cells O2 diffuses from the capillaries to the tissue and CO2 diffuses from the tissue to the capillaries. 37 12 1/20/2023 Lung Capacities Lung Capacities • The full capacity of your lungs is not used up under normal conditions - consider yawning, or blowing out a candle, or exercising. • A spirometer is used to measure lung capacities and produces a spirograph 38 • Tidal Volume: volume of air inhaled and exhaled in a normal breathing movement 39 13 1/20/2023 Lung Capacities Lung Capacities • Expiratory Reserve Volume: the additional volume that can be forced out of lungs • Vital Capacity: the total volume of gas that can be moved in or out of the lungs • Inspiratory Reserve Volume: the additional volume of air that can be taken in, beyond a regular or tidal inhalation. • Inspiratory Capacity: total volume of air that can be taken in =(TV + IRV) TV + IRV + ERV = VC IRV IRV ERV 40 41 14 1/20/2023 Lung Capacities • Residual Volume: the amount of gas that remains in the lungs and passageways of the respiratory system even after full exhalation (prevents collapse, no value for gas exchange) 42 15