ANAT THURS OCT 28
FRIENDLY REMINDER TO MAKE UP
ANY MISSED TESTS OR QUIZZES &
TURN IN ANY MISSING
ASSIGNMENTS BY TOMORROW.
(REPORT CARDS ARE DUE)
I WILL BE AROUND AFTER SCHOOL
TODAY
Functions of the skin that declines with age.
• Flattening of the dermal-epidermal junction,
increased susceptibility to friction/ shearing forces
resulting in blistering.
• Decreased sensitivity to pain perception
• Epidermis becomes thinner and flatter , uneven
distribution of melanocytes leading to uneven
pigmentation.
• Skin becomes wrinkled due to depletion of
elastic fibers.
• Skin becomes dry as a result of atrophy of
sebaceous glands
How do wounds heal?
WARNING: THERE ARE
SOME GROSS, SCARY
PICTURES COMING
Classification of wound healing
• Wounds that heal by
primary intention e.g.
incisional wounds
• Wounds that heal by
secondary intention
e.g. pressure ulcers
• Wounds that heal by
tertiary intention e.g.
delayed suture
4
Acute wounds
Characterised by:
•
•
•
•
No underlying trauma
Short duration
Normal inflammatory phase
Heal and do not breakdown
5
Chronic wounds
Characterised by:
• Underlying pathology not enough blood
flow
• Prolonged duration
• Hyperactive state
• Persistent state of inflammation
6
Wounds go through 4 distinct phases
Normal Wound Healing Response
Proteoglycans
Neutrophils
Fibroblasts
Collagen
remodelling
Collagen
Scar maturation
Angiogenesis
MATURATION
Macrophages
Platelets
Lymphocytes
Fibrin
PROLIFERATION
INFLAMMATION
HAEMOSTASIS
MINUTES
DAYS
WEEKS
MONTHS / YEARS
STAGE 1: BLEEDING
•Starts immediately after
injury.
•Blood vessel contraction
(vasoconstriction)
STAGE 2: INFLAMMATION
•Occurs between 0-3
days
STAGE 3: Proliferation
•0-24 days
STAGE 4: Maturation
•20 days – 2 years
•Closure of wound and
re-epithelisation.
•Scar maturation
Factors Affecting Healing
(WHOLE BODY)
•Age
•Anemia
•Nutrition
• Medications e.g.: Anti inflammatory, Cytotoxic
drugs, steroids
•Chronic health conditions eg :Diabetes Mellitus
•Systemic infection
•Oxygenation
•Smoking
•Psychological factors
•Temperature
Factors affecting healing
Local Factors
•Blood supply
•Denervation
•Hematoma
•Local Infection
•Duration
•Wound bed condition
•Anatomical site
•Size of wound
What we are doing today :)
GROUPS OF 4
EVERYTHING DUE MONDAY
COMPLETE AN
INDIVIDUAL
LAB PAPER TO
TURN IN
AS A GROUP
OF 4 TURN IN
ONE PHOTO
UPLOAD TO
GOOGLE
CLASSROOM