ACTIVE LEARNING TEMPLATE: Medication Fredy Ortiz STUDENT NAME______________________________________ Tocolytic MEDICATION___________________________________________________________________________ REVIEW MODULE CHAPTER____________ CATEGORY CLASS__tocolytic/adrenergics _____________________________________________________________________ PURPOSE OF MEDICATION Expected Pharmacological Action Stimulates beta-adrenergic receptors in the uterus, resulting in uterine relaxation. Therapeutic Use Decreased intensity and frequency of premature uterine contractions. Complications CNS: headache, anxiety, nervousness CV: Pulmonary Edema, angina, hypotension, tachycardia (maternal and fetal) GI: nausea, vomiting, drug-induced hepatitis Derm: erythema Hemat: agranulocytosis, leukopenia Endo: hyperglycemia Neuro: tremors Medication Administration IV (Adults): 50–100 mcg/min, increased q 10 min by 50 mcg/min until desired response is obtained or maternal heart rate reaches 130 bpm, followed by maintenance infusion at 150–350 mcg/min. Contraindications/Precautions Hypersensitivity,Cardiovascular disease or uncontrolled hypertension, Uncontrolled hyperthyroidism, Pheochromocytoma, Chorioamnionitis, Hypovolemia, Pulmonary hypertension, Eclampsia,Intrauterine fetal death or nonreassuring fetal status, Pregnancy less than 20 weeks. Abruptio placentae or placenta previa, Pre-eclampsia, Hypertension, History of migraine headache, Diabetes mellitus. Interactions Corticosteroids may increase the risk of hyperglycemia or fluid retention. Additive adrenergic effects may occur with sympathomimetics or other adrenergics. Beta blockers may negate the beneficial effects of ritodrine. Evaluation of Medication Effectiveness Decreased intensity and frequency of premature uterine contractions. Discontinue ritodrine as soon as labor is irreversible to allow for metabolic recovery before delivery. ACTIVE LEARNING TEMPLATES Nursing Interventions Assess uterine activity frequently throughout therapy. Assess gestational age and fetal maturity to determine premature labor. Monitor maternal BP and pulse and fetal heart rate frequently throughout administration. Monitor intake and output ratios for significant discrepancies in totals. Assess patient frequently during IV infusion for signs and symptoms of pulmonary edema Client Education Instruct patient to notify health care professional immediately if contractions begin again or if water breaks. Therapeutic Procedure A7