Passive Transport cont... C. Facilitated diffusion - Movement of molecules that can't easily diffuse across membrane (too large, insoluble in lipids) - facilitated by carrier proteins A. Slower than regular diffusion B. Still no energy required (going from high to low) C. Ex. Glucose How is a crossing guard like a carrier protein? Glucose binds to protein, changes shape so it can cross hydrophobic interior, then released Types of Active Transport: Basics: - Movement of material up a concentration gradient (requires energy input) - Most energy needed is ATP - Carried by Cell Membrane “Pumps” that move material from low to high concentrations A. Sodium – Potassium Pump 1. Transports Sodium and Potassium against their concentration gradients a) 3 Na+ move out of the cell b) 2 K+ move into the cell c) This creates an electrical gradient (cell is positively charged) * Used in many things including creating nerve impulses Sodium – Potassium pump (see 2 K+ and 3 Na+ ions moving) Active Transport cont. B. Endocytosis and Exocytosis 1. Endocytosis – cells ingest macromolecules & large particles a) Can even be other cells b) Cell membrane folds over the particle & forms a vesicle c) 2 types: 1. Pinocytosis – engulfing of small solutes or fluids (cellular drinking) 2. Phagocytosis – engulfing of big particles (cellular eating) Once particle has been engulfed, it will fuse with a lysosome to digest it * How body destroys harmful bacteria & viruses Which picture below shows pinocytosis and which shows phagocytosis? The dots are liquids B A How does Pac Man feed? 2. Exocytosis – releases particles into external environment a) Used by the nervous system and endocrine(glands) system - releases hormones & molecules that control activities of other cells Exocytosis releases material outside of cell