LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034
B.Sc. DEGREE EXAMINATION – PLANT BIOLOGY & PLANT BIO-TECH.
FIFTH SEMESTER – April 2009
VE 14
PB 5405 / PB 5401 - MEDICAL MICROBIOLOGY
Date & Time: 28/04/2009 / 1:00 - 4:00 Dept. No.
Max. : 100 Marks
PART A
(20 marks)
Answer All questions
I Choose the Correct Answer
(5 x 1 = 5 marks)
01. Match A) Jenner B) Metchnikoff C) Ehrlich D) Twort with i) Phagocytosis
ii) Vaccination iii) Phage iv) Chemotheraphy
a) A-ii, B-i, C-iv, D) iii
b) A-ii, B-i, C-iii, D) iv
c) A-ii, B-iv, C-i, D) iii
d) A-ii, B-iii, C-iv, D) i
02. Statement A: Sulfonamides are semisynthetic drugs.
Statement B: Mode of action is competitive inhibition.
a) Statement A is correct, but B is incorrect
b) Statement A is incorrect, but B is correct
c) Both A and B are correct
d) d) Both A and B are incorrect
03. Which of the following is a prominent resistant flora of vagina?
a. E. coli
b. Staphylococcus
c. Lactobacillus
d. Salmonella
04. The causal organism of chicken pox is a:
a. Fungus
b. Protozoan
c. Bacterium
d. Virus
05. The vector for malarial parasite is:
a. Male Anopheles
b. Female Anopheles
c. Male Qulex
d. Female Qulex
II State whether the following statements are True or False.
(5 x 1 = 5 marks)
06. Autoclave is used in dry heat sterilization.
07. Nystatin is an antifungal antibiotic.
08. Agglutination is the most striking of all test tube antigen-antibody reactions.
09. Histoplasmosis is an example for systemic fungal infection.
10. Typhus fever is a vector borne disease caused by Rickettsia.
III. Complete the following
(5 x 1 = 5 marks)
11. Application of silver nitrate to the eyes of newborn to control ophthalmic ____________
is called Credes method.
12. ___________ acremonium is the source for the antibiotic cephalosporin.
13. Transmission of disease is otherwise known as _______________.
14. Rice water stool is the most prominent symptom of _______________.
15. Hydrophobia is associated with the disease _______________.
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IV. Answer the following, each in about 50 words
16. What is fumigation?
17. Mention any two features of chemotherapeutic agents.
18. Enumerate any two points about external defense mechanisms.
19. Write down any two morphological characteristics of Mycobacterium.
20. Name any two genera of dermatophytic fungi.
(5 x 1 = 5 marks)
PART B
(5 x 8 = 40 marks)
Answer any five, each within 350 words only. Draw diagrams and flowcharts wherever
necessary.
21. Enumerate the characteristics of an ideal antimicrobial chemical agent. Add a note an
phenol .
22. Write about the salient aspects of antibiotic sensitivity tests.
23. Distinguish between exotoxins and endotoxins in tabular form.
24. Discuss the causal organism, symptoms and control of chicken pox.
25. Bring out the differences between Syphilis and Gonorrhea based on causal organism,
symptoms and incubation period.
26. Expand the following with a foot note each:
a) HTST
b) MIC
c) NMF
d) HBV
27. Define the following:
a) Lockjaw b) Cold sterilization
c) Chemotherapy
d) Inflammation
28. Write about the following:
a. Symptoms and treatment of amoebiasis
b. Causal organism of Tetanus
c. Acids and alkalies as chemical agent of control
d. Grieseofulvin
PART C
(2 x 20 = 40 marks)
Answer the following, each within 1500 words only. Draw diagrams and flowcharts wherever
necessary.
29. a) Given an account on control of microbes by physical agents
(or)
b) Give an outline of immunity. Add a note on blood as internal defense mechanism.
30. a) Discuss the structure of HIV. Write about the symptoms, treatment and control of AIDS
(or)
b) Describe in detail the causal organisms, symptom, lab diagnosis and prevention of
Cholera.
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