LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034
M.Sc. DEGREE EXAMINATION – BIOMED.INSTRUMENTATION SC.
TM 13
THIRD SEMESTER – APRIL 2007
BI 3806 / 3801 - TECHNICAL PATHOLOGY
Date & Time: 24/04/2007 / 9:00 - 12:00
Dept. No.
SECTION-A
Answer all the questions
1. Enumerate the factors that increase the risk of folliculities.
Max. : 100 Marks
(10 x 2 =20)
2. What types of treatment are used for melanoma?
3. Define “Programmed cell death”
4. What are the objectives of honing?
5. Comment on the importance of clearing agents.
6. What is “Pityriasis Alba”?
7. Distinguish Metaplasia from Dysplasia.
8. What is Sjogren’s syndrome?
9. Explain the importance of histochemistry.
10. What is a herpes virus?
SECTION-B
Answer any four
11. Explain the freezing microtome and its applications.
(4 x 10 =40)
12. Can melanoma be treated? If so what types of treatment are used? Add note on
the methods of treatment.
13. Describe the techniques of honing and stropping with neat diagram.
14. Describe the histochemical technique for carbohydrate by PAS.
15. Explain the morphology of reversible cell injury.
16. Which is the staining method introduced by Yasuma & Ichikawa? Write the exact
protocol in detail.
SECTION-C
Answer any Two
(2 x 20 = 40)
17. Write down the steps of “Paraffin embedding technique” for section cutting with suitable diagrams.
18. Explain the metabolic steps and the pathological changes involved in fatty changes in the liver.
19. Explain the sequence of events in irreversible cell injury in ischaemia with a flow chart’
20. Explain in detail the molecular mechanism of Apoptosis.
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