LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034 B.Sc. DEGREE EXAMINATION – ADVANCED ZOOLOGY & BIOTECH. FIFTH SEMESTER – April 2009 UF 39 AZ 5506 - CELL BIOLOGY & GENETICS Date & Time: 24/04/2009 / 1:00 - 4:00 Dept. No. Max. : 100 Marks SECTION-A Answer ALL the following question in a few sentences (10 x 2 = 20marks) 1. What is vital stain? Give an example. 2. Define fixation. Name any two fixatives. 3. Differentiate osmosis from diffusion. 4. What are passive transport and active transport? 5. Differentiate karyoplast from cytoplast. 6. What are primary and secondary lysosomes. 7. Distinguish nucleoside from nucleotide. 8. What are initiation and termination codons? 9. Define holandric gene. 10. What are inbreeding and out breeding? SECTION-B Answer any FOUR of the following (4 x 10 = 40marks) 11. Give an account of cell fractionation and differential centrifugation. 12. Explain the different models of structure of plasma membrane. 13. Describe the structure and functions of Golgi complex. 14. Give an account of cytology of cancer. 15. Describe Hardy-Weinberg law with one suitable example. 16. Explain sex linked genes and its inheritance in man. SECTION-C Answer any TWO of the following (2 x 20 = 40marks) 17. Give an account of principle and working mechanism of phase contrast microscope. 18. Describe the ultra structure and function of mitochondria. 19. Describe in detail polytene and lampbrush chromosomes. 20. Give a detailed account on inherited genetic disorders in human. ******************