LOYOLA COLLEGE (AUTONOMOUS), CHENNAI – 600 034 B.Sc. DEGREE EXAMINATION – ADVANCED ZOOLOGY & BIOTECH. FIFTH SEMESTER – APRIL 2012 AZ 5513 - GENETICS Date : 30-04-2012 Time : 9:00 - 12:00 Dept. No. Max. : 100 Marks PART – A Answer ALL the questions: (10x2=20marks) 1. Define epistasis. 2. What is incomplete dominance? 3. What is Rh incompatibility? 4. What is Thalassemia? 5. What is transduction? 6. What is Hfr? 7. What is a karyotype? 8. What is pedigree analysis? 9. What is transposons? 10. Explain artificial insemination. PART–B Answer any FOUR questions: (4x10=40marks) 11. Explain the laws of segregation with suitable examples. 12. Discuss the “one gene-one polypeptide” concept with an example. 13. Explain the lac operon concept in prokaryotes. 14. Explain the maternal inheritance of shell coiling in snail. 15. Write a note on genetic counseling. 16. What is amniocentesis? Elaborate on the procedure and its application. PART- C Answer any TWO questions: (2×20=40marks) 17. Write an essay on chromosomal disorders in man. 18. Explain the complimentary genes and epistatis with suitable example. 19. Define Hardy Weinberg law of equilibrium and explain the factors affecting the equilibrium. 20. Write a detailed account on the steps involved in the gene cloning techniques. $$$$$$$