Muscle Anatomy and Physiology Chapter 9 I. Lecture Aspect A. Describe four ways skeletal muscles function. B. Study the organization of skeletal muscle from its gross anatomy to its microscopic anatomy. (Figs. 9.1 and 9.2) 1. Relate the following connective tissues to the organization of skeletal muscle: epimysium, perimysium, and endomysium. 2. Describe how blood vessels and nerves interact with skeletal muscle. 3. Relate the following structures to the microanatomy of skeletal muscle fibers (fig. 9.5): a. Sarcolemma and transverse tubules b. Myofibrils and sarcomeres with their myofilaments, actin and myosin c. Sarcoplasmic reticulum and terminal cisternae d. Sarcomere organization: z lines, actin, myosin, I band, and A band e. Thin filaments: F actin, tropomyosin, and troponin f. Thick filaments: myosin and cross-bridges C. Develop a thorough understanding of the physiological mechanisms responsible for muscle contraction. 1. sliding filament theory (P. 284) 2. Neuromuscular junction: synaptic junction, synaptic cleft, acetylcholine, acetylcholinesterase (AChE) ( fig. 9.9) 3. Action potential and excitation-contraction coupling (fig. 9.9 and 9.10) D. Describe completely the contraction cycle. E. Relate the following terms, conditions, and processes to muscle mechanics: (PP.297-300) 1. Components of a single muscle twitch (P. 293) 2. Wave summation 3. Tetanus 4. Muscle tone (tonus) 5. Treppe 6. Muscle fatigue F. Describe a motor unit. (P. 289) G. Contrast isotonic and isometric contractions. Which type contraction is utilized when the body is in tone? (Fig. 9.18) H. What are antagonistic sets of muscles? I. Describe the following steps of cellular respiration. (PPs 297-299) 1. Anaerobic steps (glycolysis) a. ATP production b. Biproducts – NADH2 and pyruvate J. K. L. M. N. O. P. Q. II. 2. Aerobic steps (Krebs cycle and Cytochrome Hydrogen Transport system) a. ATP production b. Biproducts – NADH2, FADH2, CO2, and H2O Describe the conditions necessary for an oxygen debt to occur. List the causes for muscle fatigue. Describe how lactic acid forms and how it is removed and recycled. Compare ATP and creatine phosphate. (P. 316) Contrast the three major types of skeletal muscle fibers: fast fibers, slow fibers, and intermediate fibers. (Table 9.2) Contrast anaerobic and aerobic endurance. Describe the following conditions: (PPs. 327-328) 1. muscle hypertrophy 2. muscle atrophy 3. rigor mortis 4. fibrosis 5. myalgia 6. hyperplasia 7. Duchenne Muscular Dystrophy (DMD) Describe the effects of aging on the muscular system. Contrast cardiac, smooth, and skeletal muscle tissue. (Table 9.3) 1. structural differences 2. functional differences 3. Describe the intercalated discs found in cardiac muscle. 4. What type cell junction is associated with cardiac muscle? Associated Laboratory Studies: Muscle Identification (Chapter 10) A. Using the figures shown on pages 326 and 327, locate and learn the following muscles: Note: Know the origin and insertion points as well as action of those with asterisks (*). Use your lecture textbook for this lab exercise. 1. frontalis 2. orbicularis oculi 3. orbicularis oris 4. masseter 5. zygomaticus *6. sternocleidomastoideus 7. temporalis 8. pectoralis major 9. transverses abdominis 10. serratus anterior 11. external and internal intercostals 12. rectus abdominis 13. internal and external oblique *14. deltoid 15. 16. 17. 18. 19. *20. 21. 22. 23. 24. 25. 26. 27. 28. biceps brachii brachiroadialis iliopsoas adductor longus adductor magnus rectus femoris coracobrachialis vastus lateralis vastus medialis gracillis occipitalis trapezius latissium dorsi triceps brachi 29. *30. 31. *32. *33. *34. 35. gluteus maximus gluteus medius biceps femoris semitendinosus semimembranosus gastrocnemius sartorius B. CLOSE UPS: 1. 2. 3. 4. 5. Head-lateral Muscles of thorax Muscles of abdominal wall Anterior leg muscles Posterior leg muscles C. Rotator Cuff Muscles (PPs 350-351) 1. 2. 3. 4. supra spinatus infra spinatus subscapularis teres minor 36. 37. 38. 39. 40. 41. tibialis anterior brachialis diaphragm splenius capitis platysma soleus Textbook pages Pg. 331 Pg. 343, 347, 348, 351 Pg. 343 Pg. 364 Pg. 367