3/11/2015 The Exposure Index for Digital Radiography (IEC 62494-1 and AAPM Report 116) S. Jeff Shepard, MS, DABR, FAAPM Imaging Physics Department Diagnostic Imaging Division The University of Texas M. D. Anderson Cancer Center Houston, Texas Acknowledgement: Michael Flynn, PhD AAPM Spring Clinical Meeting 2015 MDACC Imaging Physics Henry Ford Hospital 1 System Learning Objectives • Recognizing good technique in DR - Noise • Understand causes and solutions to “exposure creep” • Understand IEC/TG116 Exposure Index • Verifying EI calibration in the clinic • Be aware of additional recommendations in TG116 MDACC Imaging Physics 2 Identifying Correct Clinical Technique Recognizing Bad Images • In the film-screen world, under- and over- exposures were easily recognized by the appearance of the recorded image – Repeat at a higher or lower technique based on optical density MDACC Imaging Physics 3 1 3/11/2015 Identifying Correct Clinical Technique Recognizing Bad Images • With Digital Radiography, under- and over-exposures are not so easily recognized – Adequate images over a much wider range of exposure – Post-processing can hide mistakes – Excellent dynamic range may have down-sides MDACC Imaging Physics 4 Exposure Indices MDACC Imaging Physics 5 Exposure Indices MDACC Imaging Physics 6 2 3/11/2015 Exposure “Creep” • Under-Exposure – Higher noise – Detail visibility suffers • Over-Exposure – Lower noise (“Pretty” – improved SNR) – High patient dose • Radiologists may complain about noise, but not usually about over-exposure – Technologists learn quickly how to avoid criticism – If no one is paying attention, exposures will “creep” up. 7 MDACC Imaging Physics Exposure “Creep” Widely known problem that’s been around for a long time • Freedman M, Pe E, Mun SK, Lo SCB, Nelson M, “The potential for unnecessary patient exposure from the use of storage phosphor imaging systems,” SPIE 1897:472-479 (1993). • Gur D, Fuhman CR, Feist JH, Slifko R, Peace B, “Natural migration to a higher dose in CR imaging,” Proc Eighth European Congress of Radiology, Vienna Sep 12-17, 154 (1993). 8 MDACC Imaging Physics Vendor-Specific Indices Manuf. Index Lin or Log Exposure relation Std kV/Filter Cal Agfa lgM Log Direct 75/1.5 mm Cu 1.96 bel @ 2.5 uGy Alara EIV Log Direct 70/7.1 mm HVL 2000 mbel @ 10 µGy Canon EXP Linear Direct 80/8.2 mm Al 2000 @ 10 µGy Canon REX Linear Direct -- 106 @ 10 µGy* Carestream EI Log 80/0.5 Cu + 1 Al 3000 @ 1 mR Fuji Linear Inverse 80/3 mm Al “Total” 200@1 mR 2.85 @ 0.5 mAs S Direct GE UDExp Linear Direct 80/21 mm Al Imaging Dynamics SE Linear Inverse 80/1 mm Cu 200 @ 10 uGy Konika S Linear Inverse 80/3 mm Al “Total” 200@1 mR 70/7.1 mm HVL Philips EI_s Linear Inverse Siemens EXI Linear Direct 70/0.6 mm Cu MDACC Imaging Physics 400 @ 2.53 µGy 100 @ 1 uGy 9 3 3/11/2015 Exposure Indices IEC 62494-1 & AAPM TG116 • Recommendation for a standard detector exposure index for all digital radiography • Published 2008 • Mike Flynn and Jeff Shepard represented the USA (USNC TAG members) and AAPM on the IEC working group MDACC Imaging Physics 10 Exposure Index – IEC Exposure Index (EI): • Index is proportional to the air Kerma that the detector would have received under standard beam conditions for the same raw pixel value in the relevant image region. • Calibrated for the imaging system over the specified operating range of image receptor air kerma such that: EI = (100 uGy-1) * KCAL where KCAL is the image receptor air kerma in μGy under the calibration conditions. • For Krel = 10 uGy, EI = 1000 • For Krel = 2.5 uGy, EI = 250 MDACC Imaging Physics 11 “Relevant” Image Region • Gray histogram is for the entire image. • Black histogram is for the relevant anatomic region or Values of Interest (VOI) MDACC Imaging Physics 12 4 3/11/2015 “Relevant” Image Region • Gray histogram is for the entire image. • Black histogram is for the relevant anatomic region or Values of Interest (VOI) MDACC Imaging Physics 13 “Relevant” Image Region • AAPM TG116: “The median is recommended rather than the mean or mode because it is less affected by data extremes and outliers.” • IEC 62494-1: “The [indicator] shall be calculated using the mean, median, mode, trimmed mean, trimean, or other recognized statistical method for the description of central tendency of the [values] in the relevant image region.” MDACC Imaging Physics 14 Region to assess signal indicator Systems vary in the region used to assess the signal for an image. • Full Image • Regular regions • Anatomic regions (segmentation) MDACC Imaging Physics 15 5 3/11/2015 Deviation Index Both standards also call for a “Deviation Index” DI = 10 × Log10{EI/EIT(b,v)} • EIT (b,v) is a table of target values stored by body part (b) and view (v) DI = 0 is a perfect exposure DI = +1 means exposure was high/low by about 28% (one density or mAs step) • EIT tables to be customized for each site • If not customized, default value of DI is 0. 16 MDACC Imaging Physics Deviation Index • Exposure indices are saved in the DICOM header – 0018,1411 (EI) – 0018,1412 (EIT) – 0018,1413 (DI) – 0018,1405 (EI) and 0018,6000 (Sensitivity) are old and no longer recommended • DI Format: – AAPM: Decimal string with one decimal place (tracking and trend management) – IEC: Integer • Both indices change with VOI modification by the tech MDACC Imaging Physics 17 Values of interest – VOI Number of Pixels Pixel values to be filtered/re-scaled for presentation EI and DI calculated from median pixel value EI = EIT DI = 0.0 Values of Interest Pixel Value MDACC Imaging Physics 18 6 3/11/2015 VOI Recognition Failure • Gonadal shields, prosthetics, surgical mods • False EI & DI reported EI =≠ EITT -1.3 DI = 0.0 Number of Pixels EI and DI calculated from incorrect median pixel value Correct Values of Interest Incorrect Values of Interest Pixel Value 19 MDACC Imaging Physics Manual Correction of VOI Failure Tech manually returns the VOI to the proper position by reprocessing Number of Pixels Correct EI and DI calculated from new median pixel value EI = EIT DI = 0.0 Correct Values of Interest Pixel Value MDACC Imaging Physics 20 Standard Beam RQA5 is the standard beam condition • • • • RQR5 pre-filtered beam (70 kVp, 2.6 mm Al HVL) 70 kVp 21 mm added pure Al filtration 6.8 mm Al HVL But … • • • Pure Aluminum is impractical for field measurements (expensive, heavy, hard to find). An alternative is to use copper (cheap, portable and widely available). Valid substitution? MDACC Imaging Physics 21 7 3/11/2015 Beam Quality – spectral shape Report 116 reported equivalent spectral shape with RQA5 conditions and Cu/Al filtration HVL 6.8 mm Al Normalized Spectra, Cu/Al spectrum is about 2X that of RQA5 72.59 kVp 3.02 mm Al pre-filtered HVL • 21 mm type 1090 Al (99.9%) • Filtered HVL : 6.80 mm Al + + + + + • 0.5 mm Cu + 2.8 mm Al • Filtered HVL : 6.80 mm Al MDACC Imaging Physics 22 Standard Beam Report 116 illustrated how the addition of different Al filters to a Cu filter could compensate for differences in the unfiltered beam quality. Approximate Al to add to 0.5 mm Cu to achieve 6.8 mm HVL at 70 kVp. Averaged from about 25 systems tested. MDACC Imaging Physics 23 Beam Quality – IEC vs Report 116 AAPM Report 116 • • • • HVL = 6.8 mm Al Adjust Al and (if necessary) kVP to get HVL 70 ± 4 kVP 0.5 mm Cu + (0 – 4) mm Al (type 1100) – Brass acceptable as a Cu substitute – 21 mm pure Al acceptable. IEC Beam condition • • • • 70 kVP 0.5 mm Cu + 2 mm Al HVL = 6.8 +/- 0.3 mm Al Assumes 2.9 mm HVL unfiltered beam MDACC Imaging Physics 24 8 3/11/2015 Beam Quality – IEC vs Report 116 AAPM Report 116 • • • • HVL = 6.8 mm Al Adjust Al and (if necessary) kVP to get HVL 70 ± 4 kVP 0.5 mm Cu + (0 – 4) mm Al (type 1100) – Brass acceptable as a Cu substitute – 21 mm pure Al acceptable. IEC Beam condition • • • • 70 kVP 0.5 mm Cu + 2 mm Al HVL = 6.8 +/- 0.3 mm Al Assumes 2.9 mm HVL unfiltered beam MDACC Imaging Physics 25 Verifying EI calibration Verifying EI Calibration • • • • • • Check generator kV calibration/reproducibility Set up the Standard Beam HVL (add copper and adjust Al filtration) Establish a reference dosimeter away from the CR Obtain grid and table-top attenuation factors from the manufacturer Set up for a 10 µGy exposure to the detector (EI = 1000) Compare to EI that the system reports MDACC Imaging Physics 27 9 3/11/2015 Beam setup – step 1 Prior to any measurements verify that the x-ray source has acceptable exposure reproducibility (coefficient of variation < 0.03) and kV accuracy (within ± 3%) at the standardized condition. 28 MDACC Imaging Physics Beam setup – step 2 Collimate the x-ray beam to only cover the ion chamber with no more than 1 inch margins. Add 0.5 mm copper filtration at the face of the collimator. For DR systems, the detector should be covered with a lead apron or similar barrier when making the exposures for HVL determination and adjustment. 29 MDACC Imaging Physics Beam setup – step 3 Measure the HVL of the filtered beam Adjust the kVP and/or aluminium filtration within the limits specified to obtain a HVL as close as possible to 6.8 mm Al. Aluminum for HVL 70 kVP + 4 0 – 4 mm Al MDACC Imaging Physics 30 10 3/11/2015 Beam setup – step 4 (DR) The detector should be placed as far from the x-ray source as is practical, at least 100 cm. Collimate to the edges of the detector. If present, remove the grid and any other components between the ion chamber and the image detector. If any components cannot be removed, obtain the attenuation factors from the DR system or component vendor. 31 MDACC Imaging Physics Beam setup – step 4 (CR) Source Collimator For CR, the cassette should be separated from any surface that may increase backscatter from that surface, as recommended in AAPM Report 93 (TG 10). Use lead behind the plate to further reduce backscatter. Added Filtration Source to Detector Distance (maximum possible) If the detector is not square, the long axis of the detector should be perpendicular to the x-ray tube A-C axis. Lab Jack (CR only) > 25 cm (CR only) Lead (CR only) MDACC Imaging Physics 32 Beam setup – step 5 Place a calibrated ion chamber at the center of the beam approximately midway between the source and detector (Position A). All distances should be measured from the focal spot as indicated on the x-ray tube housing. Detector housing MDACC Imaging Physics 33 11 3/11/2015 Beam setup – step 6 Source Collimator Added Filtration Use lead to protect a DR detector. Source to Chamber Distance Make an exposure. Using an inverse square correction and applying the grid and table attenuation factors (if present) determine the air kerma at the detector (KCal). Source to Detector Distance (maximum possible) Ion chamber (position A) Chamber to Detector Distance Change the mAs setting to obtain a Kcal value that is in the middle of the detector’s response range (suggest 10 uGy). 34 MDACC Imaging Physics Beam setup – step 7 Source Collimator Move the ion chamber perpendicular to the tube axis such that it is at the edge of the field of view (Position B). Added Filtration Ensure that the entire ion chamber is in the radiation beam and is not shadowed by a collimator blade. Source to Chamber Distance Ion chamber (position B) Make an exposure using the mAs found earlier and determine the ratio of the air kerma at Position A to that at Position B. MDACC Imaging Physics Source to Detector Distance (maximum possible) Chamber to Detector Distance 35 Beam setup – step 8 Remove the protective lead and expose the detector again. Verify the resulting KCal by monitoring the exposure with the chamber at position B. Compare the corrected reading to the Exposure Index reported by the system/detector. EI should equal KCal *100 if properly calibrated, MDACC Imaging Physics 36 12 3/11/2015 EI Calibration EI calibration should be verified • At acceptance • Annually thereafter • After service events and software upgrades MDACC Imaging Physics 37 Rules for repeats Little clinical information on reject thresholds in literature • Van Metter and Yorkston – Chest and abdominal imaging – Wide range of patient thicknesses – Most AEC controlled images fell within the range of DI = ± 1.2. MDACC Imaging Physics 38 Rules for Repeats Emulating film/screen limits ΔOD = γ*Log10 {E2/E1}, and DI = 10*Log10 {E2/E1} So: Δ DI = 10*ΔOD / γ γ (film gamma): slope of H&D at 1.0 above B+F For an OD range of +0.3 (0.6 OD total) and γ = 2.5: Δ DI = 10 * {0.6/2.5} = 2.4 Acceptable DI range is + 1.2 MDACC Imaging Physics 39 13 3/11/2015 DI action levels (Table 2) DI EI Action Between -1.0 79% < exp < 126% and +1.0 Check for noise and clipping (always) < -1.0 < 79% of target Check for noise and consult with radiologist/management on need for repeat, investigate cause. Between +1.0 and +3.0 126% – 200% of target Repeat only if relevant anatomy is clipped or “burned out” > 3.0 > 200% of target Repeat only if relevant anatomy is clipped or “burned out”, require immediate management follow-up MDACC Imaging Physics 40 DI Action Levels Sites reporting excessive follow-up. Action levels based on screen/film emulation is admittedly arbitrary. Little or no published literature. MDACC Imaging Physics 41 DI Action Levels AAPM Report 232 To investigate the current state of practice for CR/DR Exposure and Deviation Indices based on AAPM Report 116 and IEC 62494, for the purpose of establishing achievable goals (reference levels) and action levels in digital radiography. The products of this task group will be a brief report and an updated version of Table 2 from AAPM Report #116. Jaydev Dave and Kyle Jones, Co-Chairs MDACC Imaging Physics 42 14 3/11/2015 Other TG116 Recommendations • VOI Histograms and graphical pixel overlays • Repeat/Reject logs • Import/Export of EIT tables • Export of for-processing image data • Dependence of EI on kV MDACC Imaging Physics 43 AEC and Technique Charts Still important in controlling patient exposure • AEC may need to be adjusted for CR and add-on DR – Energy dependence may not be the same as GdO2S • Technique charts are important for portables and extremities MDACC Imaging Physics 44 AEC Calibration Using EI EI should remain consistent with: • • • • Varying Varying Varying Varying energy phantom thickness AEC cell dose rate (mA) • EI should be reproducible over multiple exposures MDACC Imaging Physics 45 15 3/11/2015 What the Exposure Index is NOT for Patient dose estimation – Need beam HVL, pt. thickness, SSD and SID, grid atten, AEC pickup atten, detector assy. input atten … – If you have all these, you don’t need EI! System intercomparisons – Index says nothing about detector energy dependence, efficiency. - VOI recognition strategy will dramatically affect indices. MDACC Imaging Physics 46 Exposure Index Monitoring QC programs based on exposure indices are successful – Seibert JA, Shelton DK, and Moore EH, “Computed Radiography X-ray Exposure Trends,” Academic Radiology 3, 313-318 (1996). Katie Hulme will cover this next. MDACC Imaging Physics 47 Summary Exposure Indices • Noise, not density • Exposure creep • Exposure indices – AAPM Report 116 – IEC 62494-1 • Calibration • Rules for repeats MDACC Imaging Physics 48 16 3/11/2015 THANK YOU! jshepard@di.mdanderson.org MDACC Imaging Physics 49 References: Fredman M, Pe E, Mun SK, Lo SCB, Nelson M, The potential for unnecessary patient exposure from the use of storage phosphor imaging systems, SPIE 1897:472-479 (1993). Gur D, Fuhman CR, Feist JH, Slifko R, Peace B, Natural migration to a higher dose in CR imaging, Proc. Eighth European Congress of Radiology, Vienna,Sep 12-17, 154 (1993). Yorkston J. Flat-panel DR detectors for radiography and fluoroscopy. In: Specifications, Performance Evaluations, and Quality Assurance of Radiographic and Fluoroscopic Systems in the Digital Era, Goldman LW and Yester MV eds. Madison, WI: Medical Physics Publishing (2004)177-228. MDACC Imaging Physics 50 References: Willis CE, Thompson SK and Shepard SJ. Artifacts and Misadventures in Digital Radiography. Applied Radiology 33(1):11-20, January 2004. R.E. Alvarez, J.A. Seibert, and S. K. Thompson, Comparison of dual energy detector system performance, Medical Physics31(3), 556-565 (2004). JA Seibert, DK Shelton, and EH Moore, Computed Radiography X-ray Exposure Trends, Academic Radiology 3, 313-318 (1996). J A Seibert, et al, AAPM Report #93, “Acceptance Testing and Quality Control of Photostimulable Storage Phosphor Imaging Systems: Report of AAPM Task Group 10.” AAPM (2006) MDACC Imaging Physics 51 17 3/11/2015 References: Richard S., Siewerdsen J. H., Jaffray D. A., Moseley D. J. and Bakhtiar B., Generalized DQE analysis of radiographic and dual-energy imaging using flatpanel detectors, Med. Phys. 32 (5), May 2005, 1397 – 1415 Lehman L. A., Alvarez R. A., Macovski A., Brody W. R., Pelc N. J., Reiderer S. J., and Hall A., Generalized image combinations in dual KVP digital radiography, Med. Phys. 8 (5), Sept/Oct 1981, 659 – 667 Shepard S.J., et al, AAPM Report 116, An Exposure Index for Digital Radiography (Executive Summary), Med. Phys., 2009 MDACC Imaging Physics 52 References: IEC 62494-1, Medical electrical equipment- Exposure index of digital X-ray imaging systems Part 1: Definitions and requirements for general radiography, International Electrotechnical Commission, 2008 MDACC Imaging Physics 53 18