cllNlc lm scRrPPS II- J AND RtStARCH FOUNDAIION news .o\14{L]Nl( ATIONSI)FPARTMFNT 10666NORTII l1)RRii\ PI\l:\ R{ rAI) L A . I O L I , A (, - A I - I F O R N ] A9 ] 0 ] 7 6 1 94 5 7 - 8 2 9 ( () r r 6 l ( ) 4 s 5 f t l l l For fnfornation: Sue Pondronr IJews Bureau Manager ( 6 1 9 )5 5 4 - 8 2 9 0 , 5 5 4 - 8 1 3 3 FOR IMI4EDIATERtr,EASE # 0 6 2 9 8 9 -3t Scripps Clinic researcher receives award from Sloan-Ketterinq LA JO[,LA, June 29 division of biochenistry, Cancer Center University City resident Frank Huennekens, Ph.D., Scripps Clinic and Research Foundation, has received the C. Crester Stock Medal from I'ienorial Sloan-Kettering Cancer Center in New York. The awardr given annuall-y for outstanding research achievement in cancer chemotherapy, was presented last nonth during a slzmtrnsiumon n "Frontiers of Cancer Research, held in conjunction with the dedication cersrDny of the new Rrckefeller Research Laboratory Building aL SloanKettering. Huennekenswas honored for studies on methotrexate, a drug used in cancer chenotherapy. extensively for identifying action within the enzymedihydrofolate tumor cells. enzyme is responsible Currently, He and his colleagues were responsible reductase as the site for drug They also shcx,vedthat an elevated level for tumors becoming resistant Huenekens' research group is investigating approach in which an inert in the vicinity to drug treabnent. a ne$/ therapeutic form of the drug may become activated of trmrors. (t',tore) of the by enzymes Page 2 June 29, I9B9 062989-r3 Founder of the Scripps Clinic as its chairnnn for 22 years. and biology chenistry Diego, and is a fellcw Previouslyr Chenistry biochenistry delnrbnents at the University San Huennekens received the Paul-Levris Award in trrzlrne He also holds an Outstanding Grant from the National Cancer Institute. for more than 30 years. C-ounselors at the National and Clinical of California, of the American Academy of Arts and Sciences. along with the American Cancer Society' efforts Huennekens served He is also an adjunct professor in both the from the American Chsnical Society. Investigator division, rnvestiqation The Instituter Lns supported Huennekens' research He serves on the Board of Scientific Cancer Institute and on tLre Council for Research at the American Cancer Societv. Jl+ll rrfi