Canadian Health Measures Survey (CHMS)
Content summary for cycles 1 to 8
March 2015
2
Table of Contents
Table 1: Household Questionnaire and Specimen Collection
4
Table 2: Mobile Examination Centre (MEC) Physical Measures and Specimen Collection
6
Table 3: Mobile Examination Centre (MEC) Questionnaire
8
Table 4: Laboratory Biospecimen Tests
9
How to use this document
A blank shaded cell in the table indicates that the questionnaire topic, measure or lab test listed under the subject column is not included in the corresponding collection cycle. The cell indicates the age
ranges for which the questionnaire topic, measure or lab test is applicable.
When combining or comparing data between cycles, see the most recent instruction document for combining CHMS data, as well as the Data Dictionary and User Guide for information and relevant
procedures.
3
Table 1: Household Questionnaire and Specimen collection
Theme
Subject
Alcohol
Alcohol use
Height and weight
Weight change
Chronic conditions
Phlegm
Illicit drug use
Anthropometry
Chronic conditions
Drug / Medication use
Environmental
exposure
1
Medication use
2
Grooming product use
Hobbies
Housing characteristics
Family medical history Family medical history
General health
General health
Health utility index
3
4
Infection markers
Musculoskeletal
health
Strengths and difficulties
Hepatitis
Human papillomavirus vaccine
Toxoplasmosis
Bone health- Medication
Bone health- Menopause
Fracture history
Dietary fat consumption
Grains, fruits and vegetables consumption
5
Nutrition
Oral health
Physical activity
Meat and fish consumption
5
Meat consumption
Milk and dairy product consumption
Salt consumption
Water and soft drink consumption
Oral health
Children's physical activity
Cycle 1
2007-2009
Cycle 2
2009-2011
Cycle 3
2012-2013
12-79
6-79
18-79
6-79
6-79
14-79
6-79
6-79
6-79
6-79
6-79
6-79
6-79
6-17
6-79
12-79
3-79
18-79
3-79
3-79
14-79
3-79
12-79
3-79
6-79
6-79
6-79
6-79
6-79
6-79
6-79
6-11
3-79
3-79
3-79
3-79
6-79
6-17
3-79
9-39 F
12-79
3-79
3-79
14-79
3-79
3-79
3-79
14-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
4-17
3-79
9-59 F
4-17
3-79
Cycle 6
2018-2019
Cycle 7
2020-2021
Cycle 8
2022-2023
12-79
3-79
12-79
3-79
12-79
3-79
3-79
3-79
14-79
3-79
14-79
3-79
3-79
3-79
14-79
3-79
3-79
3-79
14-79
3-79
3-79
3-79
3-79
3-79
4-17
3-79
4-17
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
12-79
3-79
6-79
3-79
6-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
40-65 F
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-11
3-11
12-79
3-11
3-11
3-11
3-79
3-79
3-79
3-79
3-79
3-11
12-79
12-79
12-79
12-79
6
International physical activity
7
Physical activities
Cycle 4
Cycle 5
2014-2015
2016-2017
Age (years)
12-79
12-79
3-79
3-79
12-79
3-79
3-79
40-65 F
3-79
3-79
3-79
3-11
4
Table 1: Household Questionnaire and Specimen collection (continued)
Theme
Subject
Physical activity
(cont'd)
Pregnancy / Birth
Sexual health
Sleep
Smoking
Socio-demographic
characteristics
Specimen collection
Vision
8
Sedentary activities
Time spent outdoors
Neighbourhood environment
Birth information
Breastfeeding
Breastfeeding information
Maternal breastfeeding
Pregnancy
Pregnancy information
Pap smear test
Sexual behaviour
Sleep apnea
Sleep
Electronic cigarettes
Exposure to second-hand smoke
Exposure to second-hand vapor
Smoking
Education
Income
Labour force activity
Socio-demographic characteristics
Indoor air
Tap water
Vision
Cycle 1
2007-2009
Cycle 2
2009-2011
Cycle 3
2012-2013
12-79
12-79
12-79
3-14
6-11
14-79 F
6-11
14-79 F
14-59 F
6-11
3-11
14-79
3-11
14-79 F
3-11
14-79 F
14-59 F
3-11
14-79 F
14-79
14-59 F
3-11
14-79 F
14-79
6-79
3-79
3-79
3-79
6-79
3-79
3-79
3-79
12-79
12-79
6-79
15-75
6-79
12-79
15-79
3-79
15-75
3-79
3-11
Cycle 4
Cycle 5
2014-2015
2016-2017
Age (years)
12-79
12-79
3-14
3-17
3-79
3-11
3-11
14-79 F
3-11
3-11
14-79 F
14-59 F
14-59 F
3-11
3-11
14-79
12-79
12-79
15-79
15-79
3-79
3-79
15-75
15-75
3-79
3-79
Data at household level
Data at household level
14-79
18-79
Cycle 6
2018-2019
Cycle 7
2020-2021
Cycle 8
2022-2023
12-79
3-17
3-79
3-11
14-79 F
3-11
14-79 F
14-59 F
3-11
12-79
12-79
3-11
3-11
3-11
14-79 F
14-59 F
3-11
3-11
14-79 F
14-59 F
3-11
14-79
14-79
14-79
18-79
12-79
3-79
3-79
12-79
3-79
3-79
15-75
3-79
12-79
3-79
3-79
12-79
3-79
3-79
15-75
3-79
3-79
3-79
3-79
3-79
12-79
12-79
3-79
3-79
3-79
3-79
12-79
12-79
3-79
3-79
3-79
3-79
15-75
15-75
3-79
3-79
Data at household level
Data at household level
F=Females
1
Data from the Medication use questionnaire administered during the household visit is combined with data from the Medication use questionnaire administered during the mobile examination centre (MEC)
visit to form a medications data file.
Questionnaire administered during the mobile examination centre visit for cycle 2
3
Portions of the questionnaire administered during the mobile examination centre visit in cycle 3 and 4
4
Strengths and Difficulties Questionnaire© Robert Goodman
5
Fish portion of Meat and fish consumption questionnaire modified and administered during the mobile examination centre visit in cycles 2, 3 and 4
6
International Physical Activity Questionnaire (IPAQ)
7
As of Cycle 4, physical activity is divided into two blocks: one for youth (12 to 17); and one for adults (18 to 79).
8
A wide variety of lab tests are done on the specimens (see Tables 4 to 6)
2
5
Table 2: Mobile Examination Centre (MEC) Physical Measures and Specimen collection
Theme
Cycle 1
2007-2009
Cycle 2
2009-2011
Cycle 3
2012-2013
Standing height
Sitting height
6-79
6-79
3-79
3-79
3-79
3-79
Weight
Skinfolds
Waist circumference
Hip circumference
6-79
6-79
6-79
6-79
3-79
3-79
3-79
3-79
3-79
3-79
1
3-79
3-79
3-79
3-79
6-79
6-79
3-19
6-79
6-79
6-69
8-69
Subject
Anthropometry
Neck circumference
Blood pressure (resting)
Cardiovascular health
Heart rate (resting)
and fitness
Modified Canadian Aerobic Fitness Test (mCAFT step test)
Audiometry
Otoacoustic Emissions
Otoscopy
Tympanometry
Fractional Exhaled Nitric Oxide (FENO)
Hearing
Lung health
Musculoskeletal
fitness
Oral health
Physical activity
Specimen collection
Vitamin D
6-79
6-79
6-79
3-79
3-79
3-79
6-79
3-79
3-79
3-79
6-79
6-79
6-79
6-79
6-79
Cycle 6
2018-2019
Cycle 7
2020-2021
Cycle 8
2022-2023
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
6-79
6-79
3-79
6-79
6-79
6-79
6-79
6-79
6-79
8-69
8-69
6-79
6-79
6-79
6-79
Spirometry
Hand grip strength
6-79
6-79
6-79
6-79
Partial curl-ups
6-69
8-69
Sit and reach
Oral health examination
6-69
6-79
6-69
6-79
6-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
6-79
3-79
3-79
3-79
3-79 , 3-39
20-59
3-79
Accelerometry (activity monitor)
Blood
3,4
6-79
6-79
Cycle 4
Cycle 5
2014-2015
2016-2017
Age (years)
3-79
3-79
3-79
Urine
Hair
Saliva
Skin pigmentation
2
6-79
6-79
6-69
6-69
3-79
3-79
6
3-79
3-79
7
7
3-79
5
Vision
6
3-79 , 3-39
20-59
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
6-19, 20-395,
40-79
Visual acuity
6-19, 20-39 ,
40-79
Visual field
Retinal photography
20-395, 40-79 20-395, 40-79
5
5
20-39 , 40-79 20-39 , 40-79
6
Table 2: Mobile Examination Centre (MEC) Physical Measures and Specimen collection (continued)
Theme
Subject
Cycle 1
2007-2009
Cycle 2
2009-2011
Intraocular pressure
Peripheral quantitative computed tomography (pQCT)
Mechanography (multiple 2 legged hopping)
Musculoskeletal health
Mechanography (single 2 legged jump)
Vision (cont'd)
Dual-energy x-ray absorptiometry (DXA)
1
Respondents wear an activity monitor for seven days directly following their visit to the mobile examination centre
3
A wide variety of lab tests are done on blood and urine (see Table 4: Laboratory Biospecimen Tests)
4
A limited volume of blood and urine is stored for future health research
5
Vision test done on sample of respondents who self-reported being diagnosed with diabetes (type 1 and type 2)
A urine sample will also be collected at the household
7
Cycle 4
Cycle 5
2014-2015
2016-2017
Age (years)
Cycle 6
2018-2019
Cycle 7
2020-2021
Cycle 8
2022-2023
6-79
6-79
5
5
20-39 , 40-79 20-39 , 40-79
6-79
6-79
6-79
6-79
6-79
6-79
Used World Health Organization (WHO) and National Institute of Health (NIH) measurement protocols
2
6
Cycle 3
2012-2013
For the household urine sample, iodine will only be measured on respondents 3-39 years of age
7
Table 3: Mobile Examination Centre (MEC) Questionnaire
Cycle 1
2007-2009
Theme
Subject
Nutrition
Fish and shellfish consumption
Cycle 2
2009-2011
Cycle 3
2012-2013
3-79
3-79
3-79
3-79
3-79
3-79 S
3-79
3-79
3-79 S
3-79 S
3-79
3-79
6-79
3-79
3-79
3-79
3-79
6-79
6-79
3-79
3-79
3-79
3-79
3-79
1
Environmental
exposure
Hearing
Medication use
Oral health
Screening
Sun exposure
Vision
Cycle 6
2018-2019
Cycle 7
2020-2021
Cycle 8
2022-2023
3-79
3-79
3-79
3-79 S
3-79 S
3-79 S
3-79 S
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
Grooming product use
Indoor air
Tap water (water analysis questions)
Hearing ability
Noise exposure
Medication use2
Oral health
Screening questions for physical measures
Sun exposure
Vision
Cycle 4
Cycle 5
2014-2015
2016-2017
Age (years)
S=Subsample
1
Questions administered during the household questionnaire in cycle 1
2
Data from the Medication use questionnaire administered during the household visit is combined with data from the Medication use questionnaire administered during the mobile examination centre (MEC) visit to form a
medications data file.
8
Table 4: Laboratory Biospecimen Tests
Theme
Subject
Allergies
Total immunoglobulin E
Procollagen type I N-terminal propeptide
C-telopeptide of collagen type I
Apolipoprotein A1
Apolipoprotein B
Fibrinogen
High density lipoprotein cholesterol (HDL-C)
High sensitivity C-reactive protein (HsCRP)
Homocysteine
Low density lipoproteins (LDL-C)
Derived variable
Direct measure
Total cholesterol
Triglycerides
Red blood cell fatty acids
cis-Monosaturated fatty acids
cis-Vaccenic acid
Oleic acid
Palmitoleic acid
Omega-3 fatty acids
alpha-Linolenic acid
Docosahexaenoic acid
omega-3-Docosapentaenoic acid
Eicosapentaenoic acid
Eicosatetraenoic acid
Omega-6 fatty acids
Adrenic acid
Arachidonic acid
Dihomo-gamma-linolenic acid
omega-6-Docosapentaenoic acid
Bone Health
Cardiovascular
health
Biospecimen
Cycle 1
2007-2009
blood
blood
blood
blood
blood
blood
blood
blood
blood
6-79 S
6-79 S
12-79
6-79
6-79
6-79
blood
blood
blood
blood
6-79 S
6-79
6-79 S
Cycle 2
2009-2011
Cycle 3
2012-2013
6-79
20-79 S
20-79 S
Cycle 4
Cycle 5
2014-2015
2016-2017
Age (years)
6-79
6-79
6-79 S
20-79 S
20-79 S
20-79 S
20-79 S
Cycle 6
2018-2019
Cycle 7
2020-2021
Cycle 8
2022-2023
6-79
6-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
12-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
6-79 S
6-79 S
6-79 S
6-79 S
6-79 S
6-79 S
6-79 S
3-79
6-79 S
3-79
6-79 S
3-79
6-79 S
3-79
6-79 S
3-79
6-79 S
3-79
6-79 S
3-79
6-79 S
blood
blood
blood
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
blood
blood
blood
blood
blood
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
blood
blood
blood
blood
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
9
Table 4: Laboratory Biospecimen Tests (continued)
Theme
Subject
Gamma-linolenic acid
Cycle 1
2007-2009
Cycle 2
2009-2011
Cycle 3
2012-2013
Cycle 4
Cycle 5
2014-2015
2016-2017
Age (years)
blood
20-79 S
20-79 S
blood
20-79 S
20-79 S
blood
blood
blood
blood
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
blood
blood
blood
blood
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
alpha-Linolenic acid/Eicosapentaenoic acid
blood
20-79 S
20-79 S
Arachidonic acid/Eicosapentaenoic acid
Omega-3 index
Total 18:1 cis fatty acids
Total cis-monounsaturated fatty acids
Total n-3 PUFA
Total n-3 (18:4; 20:4; 20:5; 22:5; 22:6)
Total n-6 PUFA
Total n-6 (18:3; 20:3; 20:4; 22:4; 22:5)
Total n-6 PUFA/total n-3 PUFA
Total n-6 LC-PUFA/total n-3 LC-PUFA
Total polyunsaturated fatty acids
Total saturated fatty acids
Total 18:1 trans fatty acids
Total 18:2 trans fatty acids
blood
blood
blood
blood
blood
blood
blood
blood
blood
blood
blood
blood
blood
blood
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
Linoleic acid
Saturated fatty acids
Lauric acid
Myristic acid
Palmitic acid
Stearic acid
Trans fatty acids
RBC Fatty acid derived variables
Elaidic acid
Palmitelaidic acid
trans-10-Octadecenoic acid
trans-Vaccenic acid
Cardiovascular
health (Cont'd)
Biospecimen
Cycle 6
2018-2019
Cycle 7
2020-2021
Cycle 8
2022-2023
10
Table 4: Laboratory Biospecimen Tests (continued)
Theme
Subject
Cardiovascular
health (Cont'd)
Total 18:3 trans fatty acids
Total trans fatty acids
Alanine aminotransferase (ALT)
Albumin
Alkaline phosphatase (ALKP)
Aspartate aminotransferase (AST)
Bicarbonate (CO2)
Chloride
Creatinine
Gamma-glutamyl transferase (GGT)
Lactate dehydrogenase (LD)
Magnesium
Phosphorus
Potassium
Sodium
Total bilirubin (TBIL)
Calcium
Total protein (TP)
Urea
Uric acid
Hemoglobin
Hemoglobin
Mean corpuscular hemoglobin
Chemistry panel
Complete blood
count
Mean corpuscular hemoglobin concentration
Platelets
Mean platelet volume
Platelet count
Red blood cell
Hematocrit
Biospecimen
blood
blood
blood
blood
blood
blood
blood
blood
blood
blood
blood
blood
blood
blood
blood
blood
blood
blood
blood
blood
Cycle 1
2007-2009
Cycle 2
2009-2011
Cycle 3
2012-2013
20-79 S
20-79 S
6-79
6-79
6-79
6-79
6-79
6-79
6-79
6-79
6-79
Cycle 4
Cycle 5
2014-2015
2016-2017
Age (years)
20-79 S
20-79 S
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
Cycle 6
2018-2019
Cycle 7
2020-2021
Cycle 8
2022-2023
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
6-79
6-79
6-79
6-79
6-79
6-79
6-79
6-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
blood
blood
6-79
6-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
blood
6-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
blood
blood
6-79
6-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
blood
6-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
11
Table 4: Laboratory Biospecimen Tests (continued)
Theme
Biospecimen
Cycle 1
2007-2009
Cycle 2
2009-2011
Cycle 3
2012-2013
blood
6-79
3-79
3-79
3-79
Red cell distribution width
Red blood cell count (RBC)
White blood cell
Basophils
Eosinophils
Lymphocytes
Neutrophils
Monocytes
White blood cell count (WBC)
Glucose - plasma
Glucose - serum
Glycated hemoglobin A1c (HbA1c)
Insulin
blood
blood
6-79
6-79
3-79
3-79
3-79
3-79
blood
blood
blood
blood
blood
blood
blood
blood
blood
blood
6-79
6-79
6-79
6-79
6-79
6-79
6-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
6-79
6-79 S
Acrylamide hemoglobin adduct
Glycidamide hemoglobin adduct
Subject
Mean corpuscular volume
Complete blood
count (cont'd)
Diabetes
Environmental
exposure (EE) Acrylamide
tt-Muconic acid
Phenol
s-Phenylmercapturic acid
Carbofuranphenol
EE - Carbamate
insectides
2-Isopropoxyphenol
2,4-Dichlorophenol
2,5-Dichlorophenol
EE - Chlorophenols Pentachlorophenol
2,4,5-Trichlorophenol
2,4,6-Trichlorophenol
Antimony
EE - Metals and
Arsenic (speciated)
trace elements
Arsenobetaine/arsenocholine
EE - Benzene
metabolites
Cycle 6
2018-2019
Cycle 7
2020-2021
Cycle 8
2022-2023
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
6-79 S
6-79
6-79 S
6-79 S
6-79
6-79 S
3-79
6-79
6-79 S
3-79
6-79
6-79 S
3-79
6-79
6-79 S
3-79
6-79
6-79 S
blood
3-79 S
3-79 S
3-79 S
3-79 S
blood
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
urine
urine
urine
urine
urine
urine
urine
urine
urine
urine
urine
urine
6-79
6-79 S
6-79
6-79
Cycle 4
Cycle 5
2014-2015
2016-2017
Age (years)
12
Table 4: Laboratory Biospecimen Tests (continued)
Theme
Subject
Arsenocholine
EE - Metals and
trace elements
(cont'd)
Arsenic (V) acid
Arsenous (III) acid
Dimethylarsinic acid
Monomethylarsonic acid
Arsenic (total)
Arsenic (total)
Boron
Cadmium
Cadmium
Cesium
Cobalt
Cobalt
Copper
Copper
Fluoride
Lead
Lead
Manganese
Manganese
Mercury
Inorganic
Inorganic
Methyl
Total
Molybdenum
Molybdenum
Nickel
Biospecimen
Cycle 1
2007-2009
Cycle 2
2009-2011
urine
urine
urine
urine
urine
blood
urine
urine
blood
urine
urine
blood
urine
blood
urine
urine
blood
urine
blood
urine
blood
urine
blood
blood
blood
urine
blood
3-79 S
3-79 S
3-79 S
3-79 S
6-79
6-79
6-79
6-79
6-79
6-79
6-79
6-79
6-79
6-79
Cycle 4
Cycle 5
2014-2015
2016-2017
Age (years)
Cycle 6
2018-2019
Cycle 7
2020-2021
Cycle 8
2022-2023
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79
3-79
3-79 S
3-79
3-79 S
3-79 S
3-79
3-79 S
3-79
3-79
3-79 S
3-79
3-79 S
3-79
3-79
3-79
3-79
3-79
3-79
20-79 S
3-79
3-79
20-79 S
3-79
3-19 S
3-79
3-19 S
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79 S
3-79
3-79
3-79
3-79
6-79 S
6-79
6-79
6-79
6-79
6-79
Cycle 3
2012-2013
3-79
3-79
3-79
3-79
13
Table 4: Laboratory Biospecimen Tests (continued)
Theme
EE - Metals and
trace elements
(cont'd)
EE Organochlorine
pesticides
Biospecimen
Cycle 1
2007-2009
Cycle 2
2009-2011
Nickel
urine
6-79
3-79
RBC chromium
Selenium
Selenium
Silver
Silver
Thallium
Tungsten
Uranium
Uranium
Vanadium
Zinc
Zinc
Aldrin
alpha-Chlordane
gamma-Chlordane
cis-Nonachlor
trans-Nonachlor
Oxychlordane
beta-Hexachlorocyclohexane (ß-HCH)
gamma-Hexachlorocyclohexane (γ-HCH)
Hexachlorobenzene (HCB)
Mirex
p,p'-DDE
p,p'-DDT
Toxaphene parlar 26
Toxaphene parlar 50
blood
blood
urine
blood
urine
urine
urine
blood
urine
urine
blood
urine
blood
blood
blood
blood
blood
blood
blood
blood
blood
blood
blood
blood
blood
blood
Subject
6-79
6-79
6-79
6-79
6-79
6-79
6-79
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
20-79 S
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
Cycle 3
2012-2013
Cycle 4
Cycle 5
2014-2015
2016-2017
Age (years)
3-79 S
3-19 S
Cycle 6
2018-2019
Cycle 7
2020-2021
Cycle 8
2022-2023
3-79 S
3-19 S
14
Table 4: Laboratory Biospecimen Tests (continued)
Theme
Subject
Biospecimen
Cycle 1
2007-2009
Cycle 2
2009-2011
6-79 S
6-79 S
6-79 S
6-79 S
6-79 S
6-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
Acephate
Diethylphosphate (DEP)
Diethylthiophosphate (DETP)
Diethyldithiophosphate (DEDTP)
Dimethylphosphate (DMP)
Dimethylthiophosphate (DMTP)
Dimethyldithiophosphate (DMDTP)
Malathion dicarboxylic acid
Methamidophos
3,5,6 Trichloro-2-pyridinol
Butyl paraben
Ethyl paraben
Methyl paraben
Propyl paraben
Perfluorobutane sulfonate (PFBS)
Perfluorodecanoic acid (PFDA)
Perfluorohexane sulfonate (PFHxS)
Perfluorohexanoic acid (PFHA)
Perfluoro-n-butyric acid (PFBA)
Perfluorononanoic acid (PFNA)
Perfluorooctane sulfonate (PFOS)
Perfluorooctanoic acid (PFOA)
Perfluoroundecanoic acid (PFUA)
urine
urine
urine
urine
urine
urine
urine
urine
urine
urine
urine
urine
urine
urine
blood
blood
blood
blood
blood
blood
blood
blood
blood
EE - Phenoxy
Herbicide
2,4-Dichlorophenoxyacetic acid (2,4-D)
urine
6-79
3-79 S
EE - Phthalate
metabolites
Mono benzyl phthalate (MBzP)
Mono-3-carboxypropyl phthalate (MCPP)
Mono-3-hydroxy-n-butyl phthalate (3OH-MBP)
Mono cyclohexyl phthalate (MCHP)
urine
urine
urine
urine
6-49
6-49
3-79 S
3-79 S
6-49
3-79 S
EE Organophosphate
insecticides
EE - Parabens
EE - Perfluoroakyl
substances
Cycle 3
2012-2013
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
20-79
20-79
20-79
12-79 S
12-79 S
12-79 S
12-79 S
12-79 S
12-79 S
12-79 S
12-79 S
12-79 S
Cycle 4
Cycle 5
2014-2015
2016-2017
Age (years)
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79
3-79 S
3-79
3-79 S
3-79
3-79 S
3-79
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
Cycle 6
2018-2019
Cycle 7
2020-2021
Cycle 8
2022-2023
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79
3-79
3-79
3-79
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
15
Table 4: Laboratory Biospecimen Tests (continued)
Theme
EE - Phthalate
metabolites
(cont'd)
EE - Alternate
plasticizers
Biospecimen
Cycle 1
2007-2009
Cycle 2
2009-2011
Mono-(2-ethyl-5-hydroxyhexyl) phthalate
(MEHHP)
urine
6-49
3-79 S
3-79 S
3-79 S
Mono-(2-ethyl-5-oxohexyl) phthalate (MEOHP)
urine
6-49
3-79 S
3-79 S
3-79 S
Mono-2-ethylhexyl phthalate (MEHP)
Mono ethyl phthalate (MEP)
Mono-iso-butyl phthalate (MiBP)
Mono-isononyl phthalate (MNP)
Mono-n-butyl phthalate (MBP)
Mono-n-octyl phthalate (MOP)
Mono-methyl phthalate (MMP)
Mono-carboxy-n -heptyl phthalate (MCHpP)
urine
urine
urine
urine
urine
urine
urine
urine
6-49
6-49
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
Mono(2-ethyl-5-carboxypentyl) phthalate (MECP
Mono(2-carboxymethylhexyl) phthalate (MCMHP
Mono(carboxyisooctyl) phthalate (MCIOP)
Mono(oxoisononyl) phthalate (MOINP)
Mono(hydroxyisononyl) phthalate (MHINP)
Monocarboxyisononyl phthalate (MCiNP)
Monoisodecyl phthalate (MIDP)
Monooxoisodecyl phthalate (MOiDP)
Monohydroxyisodecyl phthalate (MHiDP)
urine
3-79 S
3-79 S
urine
urine
urine
urine
urine
urine
urine
urine
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
urine
3-79 S
3-79 S
urine
urine
urine
urine
urine
urine
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
Subject
Mono-isononyl-cyclohexane-1,2-dicarboxylate (M
Cyclohexane-1,2-dicarboxylic acid (CHDA)
Cyclohexane-1,2-dicarboxylic mono hydroxyison
cyclohexane-1,2-dicarboxylic mono oxoisononyl
Cyclohexane-1,2-diarboxylic mono carboxyisono
2,2,4 trimethyl-1,3, pentanediol diisobutyrate (TX
2,2,4-trimethyl-1,2-pentanediol (TMPD)
6-49
6-49
6-49
6-49
Cycle 3
2012-2013
Cycle 4
Cycle 5
2014-2015
2016-2017
Age (years)
Cycle 6
2018-2019
Cycle 7
2020-2021
Cycle 8
2022-2023
16
Table 4: Laboratory Biospecimen Tests (continued)
Theme
Subject
2,2,4-trimethyl-3-hydroxy valeric acid (HTMV)
1-mono(2-ethylhexyl)trimellitate (1-MEHTM)
EE - Alternate
2-mono(2-ethylhexyl)trimellitate (2-MEHTM)
plasticizers (cont'd)
4-mono(2-ethylhexyl)trimellitate (4-MEHTM)
1,2-di(2-ethylhexyl)trimellitate (1,2-DEHTM)
2,4-di(2-ethylhexyl)trimellitate (2,4-DEHTM)
1,4-di(2-ethylhexyl)trimellitate (1,4-DEHTM)
EE - Polyaromatic
hydrocarbons
Chrysenes
2-Hydroxychrysene
3-Hydroxychrysene
4-Hydroxychrysene
6-Hydroxychrysene
Fluoranthene
3-Hydroxyfluoranthene
Fluorenes
2-Hydroxyfluorene
3-Hydroxyfluorene
9-Hydroxyfluorene
Napthalenes
1-Hydroxynaphthalene
2-Hydroxynaphthalene
Phenanthrenes
1-Hydroxyphenanthrene
2-Hydroxyphenanthrene
3-Hydroxyphenanthrene
4-Hydroxyphenanthrene
9-Hydroxyphenanthrene
Pyrene
Biospecimen
Cycle 1
2007-2009
Cycle 2
2009-2011
Cycle 3
2012-2013
Cycle 4
Cycle 5
2014-2015
2016-2017
Age (years)
Cycle 6
2018-2019
urine
3-79 S
3-79 S
urine
urine
urine
urine
urine
urine
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
urine
urine
urine
urine
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
urine
3-79 S
3-79 S
3-79 S
urine
urine
urine
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
urine
urine
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
urine
urine
urine
urine
urine
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
Cycle 7
2020-2021
Cycle 8
2022-2023
17
Table 4: Laboratory Biospecimen Tests (continued)
Theme
EE - Polyaromatic
hydrocarbons
(cont'd)
EE Polybrominated
flame retardents
EE Polychlorinated
biphenyls (PCBs)
EE - Pyrethroids
(metabolites)
EE - Tobacco
Cycle 2
2009-2011
Cycle 3
2012-2013
urine
3-79 S
3-79 S
3-79 S
1-Hydroxypyrene
Polybrominated biphenyls 153 (PBB 153)
urine
blood
3-79 S
3-79 S
3-79 S
20-79 SP
Polybrominated diphenyl ether (PBDE) 15, 17
blood
20-79 SP
PBDE 25, 28, 33, 47, 99, 100, 153
Aroclor 1260
PCB 28, 52, 66, 74, 99, 101, 105, 118,
PCB 128, 138, 146, 153, 156, 163, 167, 170
PCB 178, 180, 183, 187, 194, 201, 203, 206
Cis-3-(2,2-dibromovinyl)-2,2dimethylcyclopropane carboxylic acid (cisDBCA)
Cis-3-(2,2-dichlorovinyl)-2,2dimethylcyclopropane carboxylic acid (cisDCCA)
4-fluoro-3-phenoxybenzoic acid (4-F-3-PBA)
3-phenoxybenzoic acid (3-PBA)
trans-3-(2,2-dichlorovinyl)-2,2dimethylcyclopropane carboxylic acid (transDCCA)
Nicotine and metabolites
Anabasine
Free cotinine
Cotinine-n-glucuronide
Total cotinine
Nicotine (total)
Nicotine-n-glucuronide
Trans-3-Hydroxycotinine (total)
Trans-3-Hydroxycotinine-glucuronide
blood
blood
blood
blood
blood
20-79 SP
20-79 S
20-79 S
20-79 S
20-79 S
urine
6-79
3-79 S
3-79 S
3-79 S
urine
6-79
3-79 S
3-79 S
3-79 S
urine
urine
6-79
6-79
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
3-79 S
urine
6-79
3-79 S
3-79 S
3-79 S
urine
urine
urine
urine
urine
urine
urine
urine
12-79 S
6-79
12-79 S
12-79 S
12-79 S
12-79 S
12-79 S
12-79 S
12-79
3-79
12-79
12-79
3-79
12-79
12-79
12-79
12-79
12-79
12-79
12-79
12-79
12-79
Subject
3-Hydroxybenzo(a)pyrene
Biospecimen
Cycle 1
2007-2009
3-79
12-79
3-79
12-79
12-79
12-79
12-79
12-79
Cycle 4
Cycle 5
2014-2015
2016-2017
Age (years)
3-79
Cycle 6
2018-2019
Cycle 7
2020-2021
Cycle 8
2022-2023
18
Table 4: Laboratory Biospecimen Tests (continued)
Theme
Tobacco (cont'd)
EE - Triazine
herbicides
EE - Volatile
organic
compounds
Subject
NNK metabolites (4-(methyl-nitrosamino)-1butanone)
Free NNAL
Total NNAL
Atrazine mercapturate
Desethylatrazine
Diaminochlorotriazine
Common fuel pollutants (BTEX)
Benzene
Ethylbenzene
m- & p-Xylenes
o-Xylene
Toluene
Trihalomethanes
Bromodichloromethane
Dibromochloromethane
Tribromomethane
Trichloromethane
Other
Styrene
Alkanes
Hexane
Heptane
Furans and dioxins
Tetrahydrofuran
2,5-dimethylfuran
1,4-dioxane
Chlorinated hydrocarbons
1,1,1,2-tetrachloroethylene
1,1,2-trichloroethylene
Biospecimen
urine
urine
urine
urine
urine
Cycle 1
2007-2009
Cycle 2
2009-2011
12-79 S
12-79 S
Cycle 3
2012-2013
Cycle 4
Cycle 5
2014-2015
2016-2017
Age (years)
12-79 S
12-79 S
Cycle 6
2018-2019
12-79 S
12-79 S
12-79 S
12-79 S
Cycle 8
2022-2023
3-79 S
3-79 S
3-79 S
blood
blood
blood
blood
blood
12-79 S
12-79 S
12-79 S
12-79 S
12-79 S
12-79 S
12-79 S
12-79 S
12-79 S
12-79 S
12-79 S
12-79 S
12-79 S
12-79 S
12-79 S
12-79 S
12-79 S
12-79 S
12-79 S
12-79 S
blood
blood
blood
blood
12-79 S
12-79 S
12-79 S
12-79 S
12-79 S
12-79 S
12-79 S
12-79 S
12-79 S
12-79 S
12-79 S
12-79 S
12-79 S
12-79 S
12-79 S
12-79 S
blood
12-79 S
12-79 S
12-79 S
12-79 S
blood
blood
12-79
12-79
12-79
12-79
blood
blood
blood
12-79
12-79
12-79
12-79
12-79
12-79
12-79 S
12-79 S
12-79 S
12-79 S
blood
Cycle 7
2020-2021
12-79 S
12-79 S
12-79 S
12-79 S
19
Table 4: Laboratory Biospecimen Tests (continued)
Theme
EE - Volatile
organic
compounds
(cont'd)
EE - Other
General
characterization
Hair
Infection markers
Kidney health
Subject
Biospecimen
Cycle 1
2007-2009
Cycle 2
2009-2011
Cycle 3
2012-2013
Cycle 4
Cycle 5
2014-2015
2016-2017
Age (years)
Cycle 6
2018-2019
1,2-dichloroethane
blood
12-79
12-79
Hexachloroethane
blood
12-79
12-79
blood
blood
blood
blood
blood
urine
urine
urine
blood
urine
urine
urine
urine
12-79
12-79
12-79
12-79
12-79
3-79 S
3-79 S
3-79 S
3-79 P
12-79
12-79
12-79
12-79
12-79
3-79 S
3-79 S
3-79 S
3-79 P
3-79
3-79
20-59
3-79
3-79
20-59
Chlorobenzene
1,2-dichlorobenzene
1,4-dichlorobenzene
1,2,3-trichloropropane
Chloromethylbenzene
Bisphenol A (BPA)
Ethylene thiourea (ETU)
ortho-phenylphenol (OPP)
Pooled serum organohalogens
Triclocarban
Triclosan
Creatinine
Specific gravity
Metals
Hepatitis A, B and C profile
Hepatitis A virus antibody
Hepatitis B virus core antibody
Hepatitis B virus surface antibody
Hepatitis B virus surface antigen
Hepatitis C virus antibody
Hepatitis C RNA
Chlamydia trachomatis
Herpes simplex-2
Human Papillomavirus (HPV 6, 11, 13, 16, 18,
26, 30-35, 39, 40, 42-45, 51-54, 56-59, 61, 62,
66-74, 81-87, 89-91, 97)
Toxoplasmosis
Microalbumin
blood
blood
blood
blood
blood
blood
urine
blood
6-79
3-79 S
3-79 S
3-79
3-79
3-79
3-79
3-79 S
3-79 P
3-79 P
3-79 S
3-79 S
3-79
3-79
3-79 S
3-79
3-79
3-79 S
3-79
3-79
14-79
14-79
14-79
14-79
14-79
14-79
14-79
14-79
14-79
14-79
14-79
14-79
14-791
14-79
14-791
14-79
14-791
14-79
14-79 S
14-791
14-79
14-79 S
14-791
14-79
14-79
14-791
14-79
14-79
14-59
14-59
urine
blood
urine
Cycle 8
2022-2023
3-79
6-79
3-79 S
Cycle 7
2020-2021
14-59
14-59
14-59 F
3-79
6-79
3-79
20
Table 4: Laboratory Biospecimen Tests (continued)
Theme
Subject
Biospecimen
Cycle 1
2007-2009
Ferritin
blood
Iodine (clinic)
urine
Iodine (household)
urine
Sodium (hhld & clinic)
urine
Potassium (hhld & clinic)
urine
Parathyroid hormone
blood
Nutritional status
Red blood cell folate
blood
Vitamin B12
blood
Vitamin C (L-ascorbic acid)
blood
Vitamin D3 [(25-OH)] - plasma
blood
Vitamin D3 [(25-OH)] - serum
blood
Vitamin D3 [3-epi-25-OH]
blood
Vitamin D2 [25-OH]
blood
Estradiol (E2)
blood
Follicle-stimulating hormone (FSH)
blood
Reproductive
Luteinizing hormone (LH)
blood
hormones
Progesterone (P4)
blood
Testosterone
blood
Anti-thyroglobulin
blood
Anti-thyroid peroxidase
blood
Thyroid Status
Free thyroxine
blood
Thyroid stimulating hormone
blood
M=Males; F=Females;S=Subsample; P=Pooled Serum; EE=Environmental exposure
1
Lab test done on sample of respondents who tested positive for hepatitis B core antibody
Cycle 2
2009-2011
Cycle 3
2012-2013
6-79
3-79
3-79
3-79
3-79
6-79
6-79
3-79
3-79
3-79
6-79
3-79
3-79
3-79
6-79 S
Cycle 4
Cycle 5
2014-2015
2016-2017
Age (years)
3-79
3-79
3-79
3-39
3-39
3-79
3-79
6-79 S
3-79
3-79
3-79
3-79
3-79
3-79
6-79
6-79 F
6-79 F
6-79 F
6-79 M
3-79
3-79
3-79
3-79
6-79
6-79 F
6-79 F
6-79 F
6-79 M
3-79
3-79
3-79
3-79
Cycle 6
2018-2019
Cycle 7
2020-2021
Cycle 8
2022-2023
3-79
3-39
3-39
3-79
3-79
6-79 S
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
3-79
21