Canadian Health Measures Survey (CHMS) Content summary for cycles 1 to 8 May 2015 2 Table of Contents Table 1: Household Questionnaire and Specimen Collection 4 Table 2: Mobile Examination Centre (MEC) Physical Measures and Specimen Collection 6 Table 3: Mobile Examination Centre (MEC) Questionnaire 8 Table 4: Laboratory Biospecimen Tests 9 Table 5: Laboratory Indoor Air Sample Tests 23 Table 6: Laboratory Tap Water Sample Tests 28 How to use this document A blank shaded cell in the table indicates that the questionnaire topic, measure or lab test listed under the subject column is not included in the corresponding collection cycle. For tables 1 through 4, the cell indicates the age ranges for which the questionnaire topic, measure or lab test is applicable. For tables 5 and 6, a check mark indicates that the particular analyte was tested for in the air or water samples obtained from the respondent households. When combining or comparing data between cycles, see the most recent instruction document for combining CHMS data, as well as the Data Dictionary and User Guide for information and relevant procedures. 3 Table 1: Household Questionnaire and Specimen collection Theme Subject Alcohol Alcohol use Height and weight Weight change Chronic conditions Phlegm Illicit drug use Anthropometry Chronic conditions Drug / Medication use Environmental exposure 1 Medication use 2 Grooming product use Hobbies Housing characteristics Family medical history Family medical history General health General health Health utility index 3 Strengths and difficulties4 Hepatitis Infection markers Human papillomavirus vaccine Toxoplasmosis Bone health- Medication Musculoskeletal health Bone health- Menopause Fracture history Dietary fat consumption Grains, fruits and vegetables consumption 5 Nutrition Oral health Physical activity Meat and fish consumption Meat consumption5 Milk and dairy product consumption Salt consumption Water and soft drink consumption Oral health Children's physical activity International physical activity6 7 Physical activities Cycle 1 2007-2009 Cycle 2 2009-2011 Cycle 3 2012-2013 12-79 6-79 18-79 6-79 6-79 14-79 6-79 6-79 6-79 6-79 6-79 6-79 6-79 6-17 6-79 12-79 3-79 18-79 3-79 3-79 14-79 3-79 12-79 3-79 3-79 3-79 14-79 3-79 3-79 3-79 14-79 3-79 3-79 3-79 3-79 3-79 6-79 6-17 3-79 9-39 F 3-79 3-79 3-79 3-79 3-79 3-79 4-17 3-79 9-59 F 4-17 3-79 6-79 6-79 6-79 6-79 6-79 6-79 6-79 6-11 12-79 Cycle 4 Cycle 5 2014-2015 2016-2017 Age (years) 12-79 12-79 3-79 3-79 Cycle 6 2018-2019 Cycle 7 2020-2021 Cycle 8 2022-2023 12-79 3-79 12-79 3-79 12-79 3-79 3-79 3-79 14-79 3-79 14-79 3-79 3-79 3-79 14-79 3-79 3-79 3-79 14-79 3-79 3-79 6-79 3-79 6-79 3-79 3-79 3-79 3-79 4-17 3-79 4-17 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 12-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 40-65 F 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-11 3-11 12-79 3-11 3-11 3-11 3-79 3-79 3-79 3-79 3-79 3-11 12-79 12-79 12-79 12-79 12-79 3-79 3-79 40-65 F 3-79 3-79 3-79 3-11 4 Table 1: Household Questionnaire and Specimen collection (continued) Theme Subject Physical activity (cont'd) Pregnancy / Birth Sexual health Sleep Smoking Socio-demographic characteristics Specimen collection 8 Sedentary activities Time spent outdoors Neighbourhood environment Birth information Breastfeeding Breastfeeding information Maternal breastfeeding Pregnancy Pregnancy information Pap smear test Sexual behaviour Sleep apnea Sleep Electronic cigarettes Exposure to second-hand smoke Exposure to second-hand vapor Smoking Education Income Labour force activity Socio-demographic characteristics Indoor air Tap water Vision Cycle 1 2007-2009 Cycle 2 2009-2011 Cycle 3 2012-2013 12-79 12-79 12-79 3-14 6-11 14-79 F 6-11 14-79 F 14-59 F 6-11 3-11 14-79 3-11 14-79 F 3-11 14-79 F 14-59 F 3-11 14-79 F 14-79 14-59 F 3-11 14-79 F 14-79 6-79 3-79 3-79 6-79 3-79 12-79 12-79 6-79 15-75 6-79 12-79 15-79 3-79 15-75 3-79 3-11 3-79 Cycle 4 Cycle 5 2014-2015 2016-2017 Age (years) 12-79 12-79 3-14 3-17 3-79 3-11 3-11 14-79 F 3-11 3-11 14-79 F 14-59 F 14-59 F 3-11 3-11 14-79 Cycle 6 2018-2019 Cycle 7 2020-2021 Cycle 8 2022-2023 12-79 3-17 3-79 3-11 14-79 F 3-11 14-79 F 14-59 F 3-11 12-79 12-79 3-11 3-11 3-11 14-79 F 14-59 F 3-11 3-11 14-79 F 14-59 F 3-11 14-79 14-79 14-79 18-79 14-79 18-79 12-79 3-79 3-79 12-79 3-79 3-79 15-75 3-79 12-79 3-79 3-79 12-79 3-79 3-79 15-75 3-79 3-79 3-79 12-79 12-79 15-79 15-79 3-79 3-79 15-75 15-75 3-79 3-79 Data at household level Data at household level 3-79 3-79 12-79 12-79 3-79 3-79 3-79 3-79 12-79 12-79 3-79 3-79 3-79 3-79 15-75 15-75 3-79 3-79 Data at household level Data at household level 3-79 3-79 Vision F=Females 1 Data from the Medication use questionnaire administered during the household visit is combined with data from the Medication use questionnaire administered during the mobile examination centre (MEC) visit to form a medications data file. Questionnaire administered during the mobile examination centre visit for cycle 2 3 Portions of the questionnaire administered during the mobile examination centre visit in cycle 3 and 4 4 Strengths and Difficulties Questionnaire© Robert Goodman 5 Fish portion of Meat and fish consumption questionnaire modified and administered during the mobile examination centre visit in cycles 2, 3 and 4 6 International Physical Activity Questionnaire (IPAQ) 7 As of Cycle 4, physical activity is divided into two blocks: one for youth (12 to 17); and one for adults (18 to 79). 8 A wide variety of lab tests are done on the specimens (see Tables 4 to 6) 2 5 Table 2: Mobile Examination Centre (MEC) Physical Measures and Specimen collection Theme Cycle 1 2007-2009 Cycle 2 2009-2011 Cycle 3 2012-2013 Standing height Sitting height Weight Skinfolds Waist circumference 6-79 6-79 6-79 6-79 6-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 1 3-79 3-79 Hip circumference 6-79 3-79 3-79 3-79 3-79 6-79 6-79 6-69 3-19 6-79 6-79 8-69 Subject Anthropometry Neck circumference Blood pressure (resting) Cardiovascular health Heart rate (resting) and fitness Modified Canadian Aerobic Fitness Test (mCAFT step test) Audiometry Otoacoustic Emissions Hearing Otoscopy Tympanometry Fractional Exhaled Nitric Oxide (FENO) Lung health Spirometry Hand grip strength Musculoskeletal Partial curl-ups fitness Sit and reach Oral health examination Oral health Physical activity Specimen collection Vitamin D 3,4 Accelerometry (activity monitor) Blood Urine Hair Saliva Skin pigmentation 2 Cycle 4 Cycle 5 2014-2015 2016-2017 Age (years) 3-79 3-79 3-79 3-79 3-79 6-79 6-79 6-79 6-79 6-79 3-79 6-79 3-79 3-79 3-79 3-79 3-79 6-79 6-79 6-79 6-79 6-79 Cycle 6 2018-2019 Cycle 7 2020-2021 Cycle 8 2022-2023 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 6-79 6-79 8-69 3-79 6-79 6-79 8-69 6-79 6-79 6-79 6-79 6-79 6-79 6-79 6-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 6-79 6-79 6-69 6-69 6-79 6-79 6-79 6-79 8-69 6-69 3-79 3-79 3-79 3-79 6-79 6-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 6-79 6-79 6-69 6-69 6 3-79 3-79 3-79 , 3-39 20-59 3-79 7 5 Vision 6 3-79 , 3-39 20-59 3-79 7 Visual acuity 6-19, 20-39 , 40-79 6-19, 20-395, 40-79 Visual field Retinal photography 20-39 , 40-79 20-39 , 40-79 20-395, 40-79 20-395, 40-79 5 5 3-79 3-79 3-79 3-79 6 Table 2: Mobile Examination Centre (MEC) Physical Measures and Specimen collection (continued) Theme Subject Vision (cont'd) Intraocular pressure Peripheral quantitative computed tomography (pQCT) Musculoskeletal health 1 Cycle 1 2007-2009 Cycle 2 2009-2011 Mechanography (multiple 2 legged hopping) Mechanography (single 2 legged jump) Dual-energy x-ray absorptiometry (DXA) Respondents wear an activity monitor for seven days directly following their visit to the mobile examination centre 3 A wide variety of lab tests are done on blood and urine (see Table 4: Laboratory Biospecimen Tests) 4 A limited volume of blood and urine is stored for future health research 5 Vision test done on sample of respondents who self-reported being diagnosed with diabetes (type 1 and type 2) A urine sample will also be collected at the household 7 Cycle 4 Cycle 5 2014-2015 2016-2017 Age (years) 5 Cycle 6 2018-2019 Cycle 7 2020-2021 Cycle 8 2022-2023 6-79 6-79 5 20-39 , 40-79 20-39 , 40-79 6-79 6-79 6-79 6-79 6-79 6-79 Used World Health Organization (WHO) and National Institute of Health (NIH) measurement protocols 2 6 Cycle 3 2012-2013 For both household and clinic urine samples, specific demographic groups will be measured for iodine 7 Table 3: Mobile Examination Centre (MEC) Questionnaire Cycle 1 2007-2009 Theme Subject Nutrition Fish and shellfish consumption Cycle 2 2009-2011 Cycle 3 2012-2013 3-79 3-79 3-79 3-79 3-79 3-79 S 3-79 3-79 3-79 S 3-79 S 3-79 3-79 6-79 3-79 3-79 3-79 3-79 6-79 6-79 3-79 3-79 3-79 3-79 3-79 1 Environmental exposure Hearing Medication use Oral health Screening Sun exposure Vision Cycle 6 2018-2019 Cycle 7 2020-2021 Cycle 8 2022-2023 3-79 3-79 3-79 3-79 S 3-79 S 3-79 S 3-79 S 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 Grooming product use Indoor air Tap water (water analysis questions) Hearing ability Noise exposure Medication use2 Oral health Screening questions for physical measures Sun exposure Vision Cycle 4 Cycle 5 2014-2015 2016-2017 Age (years) S=Subsample 1 Questions administered during the household questionnaire in cycle 1 2 Data from the Medication use questionnaire administered during the household visit is combined with data from the Medication use questionnaire administered during the mobile examination centre (MEC) visit to form a medications data file. 8 Table 4: Laboratory Biospecimen Tests Theme Subject Allergies Total immunoglobulin E Procollagen type I N-terminal propeptide C-telopeptide of collagen type I Bone Health Cardiovascular health Apolipoprotein A1 Apolipoprotein B Fibrinogen High density lipoprotein cholesterol (HDL-C) High sensitivity C-reactive protein (HsCRP) Homocysteine Low density lipoproteins (LDL-C) Derived variable Direct measure Total cholesterol Triglycerides Red blood cell fatty acids cis-Monosaturated fatty acids cis-Vaccenic acid Oleic acid Palmitoleic acid Omega-3 fatty acids alpha-Linolenic acid Docosahexaenoic acid omega-3-Docosapentaenoic acid Eicosapentaenoic acid Eicosatetraenoic acid Omega-6 fatty acids Adrenic acid Arachidonic acid Dihomo-gamma-linolenic acid omega-6-Docosapentaenoic acid Gamma-linolenic acid Biospecimen Cycle 1 2007-2009 blood blood blood blood blood blood blood blood blood 6-79 S 6-79 S 12-79 6-79 6-79 6-79 blood blood blood blood 6-79 S 6-79 6-79 S Cycle 2 2009-2011 Cycle 3 2012-2013 6-79 20-79 S 20-79 S Cycle 4 Cycle 5 2014-2015 2016-2017 Age (years) 6-79 6-79 6-79 S 20-79 S 20-79 S 20-79 S 20-79 S Cycle 6 2018-2019 Cycle 7 2020-2021 Cycle 8 2022-2023 6-79 6-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 12-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 6-79 S 6-79 S 6-79 S 6-79 S 6-79 S 6-79 S 6-79 S 3-79 6-79 S 3-79 6-79 S 3-79 6-79 S 3-79 6-79 S 3-79 6-79 S 3-79 6-79 S 3-79 6-79 S blood blood blood 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S blood blood blood blood blood 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S blood blood blood blood blood 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 9 Table 4: Laboratory Biospecimen Tests (continued) Theme Cardiovascular health (Cont'd) Chemistry Panel Subject Linoleic acid Saturated fatty acids Lauric acid Myristic acid Palmitic acid Stearic acid Trans fatty acids RBC Fatty acid derived variables Elaidic acid Palmitelaidic acid trans-10-Octadecenoic acid trans-Vaccenic acid alpha-Linolenic acid/Eicosapentaenoic acid Arachidonic acid/Eicosapentaenoic acid Omega-3 index Total cis-18:1 fatty acids Total cis-monounsaturated fatty acids Total n-3 PUFA Total n-3 (18:4; 20:4; 20:5; 22:5; 22:6) Total n-6 PUFA Total n-6 (18:3; 20:3; 20:4; 22:4; 22:5) Total n-6 PUFA/total n-3 PUFA Total n-6 LC-PUFA/total n-3 LC-PUFA Total polyunsaturated fatty acids Total saturated fatty acids Total trans-18:1 fatty acids Total trans-18:2 fatty acids Total trans-18:3 fatty acids Total trans fatty acids Alanine aminotransferase (ALT) Albumin Biospecimen Cycle 1 2007-2009 Cycle 2 2009-2011 Cycle 3 2012-2013 Cycle 4 Cycle 5 2014-2015 2016-2017 Age (years) 20-79 S blood 20-79 S blood blood blood blood 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S blood blood blood blood blood blood blood blood blood blood blood blood blood blood blood blood blood blood blood blood blood blood blood 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 3-79 3-79 6-79 6-79 3-79 3-79 3-79 3-79 3-79 Cycle 6 2018-2019 Cycle 7 2020-2021 Cycle 8 2022-2023 3-79 3-79 3-79 3-79 3-79 3-79 10 Table 4: Laboratory Biospecimen Tests (continued) Theme Chemistry Panel (Cont'd) Complete blood count Subject Alkaline phosphatase (ALKP) Aspartate aminotransferase (AST) Bicarbonate (CO2) Chloride Creatinine Gamma-glutamyl transferase (GGT) Lactate dehydrogenase (LD) Magnesium Phosphorus Potassium Sodium Total bilirubin (TBIL) Calcium Total protein (TP) Urea Uric acid Hemoglobin Hemoglobin Mean corpuscular hemoglobin Mean corpuscular hemoglobin concentration Platelets Mean platelet volume Platelet count Red blood cell Hematocrit Mean corpuscular volume Red cell distribution width Red blood cell count (RBC) Cycle 1 2007-2009 Cycle 2 2009-2011 Cycle 3 2012-2013 blood blood blood blood blood blood blood blood blood blood blood blood blood blood blood blood 6-79 6-79 6-79 6-79 6-79 6-79 6-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 6-79 6-79 6-79 6-79 6-79 6-79 6-79 6-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 blood blood blood 6-79 6-79 6-79 blood blood blood blood blood blood Biospecimen Cycle 4 Cycle 5 2014-2015 2016-2017 Age (years) 3-79 3-79 3-79 3-79 Cycle 6 2018-2019 Cycle 7 2020-2021 Cycle 8 2022-2023 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 6-79 6-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 6-79 6-79 6-79 6-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 11 Table 4: Laboratory Biospecimen Tests (continued) Theme Complete blood count (Cont'd) Diabetes Environmental exposure (EE) Acrylamide Subject Cycle 1 2007-2009 Cycle 2 2009-2011 Cycle 3 2012-2013 Cycle 4 Cycle 5 2014-2015 2016-2017 Age (years) Cycle 6 2018-2019 Cycle 7 2020-2021 Cycle 8 2022-2023 6-79 6-79 6-79 6-79 6-79 6-79 6-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 6-79 6-79 S 6-79 S 6-79 6-79 S 6-79 S 6-79 6-79 S 3-79 6-79 6-79 S 3-79 6-79 6-79 S 3-79 6-79 6-79 S 3-79 6-79 6-79 S White blood cell Basophils Eosinophils Lymphocytes Neutrophils Monocytes White blood cell count (WBC) Glucose - plasma Glucose - serum Glycated hemoglobin A1c (HbA1c) Insulin blood blood blood blood blood blood blood blood blood blood Acrylamide hemoglobin adduct blood 3-79 S 3-79 S 3-79 S 3-79 S Glycidamide hemoglobin adduct blood 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 20-59 20-59 20-59 20-59 3-79 S 3-79 S tt-Muconic acid Phenol s-Phenylmercapturic acid Carbofuranphenol EE - Carbamate insectides 2-Isopropoxyphenol 2,4-Dichlorophenol 2,5-Dichlorophenol EE - Chlorophenols Pentachlorophenol 2,4,5-Trichlorophenol 2,4,6-Trichlorophenol Aluminum Antimony Antimony EE - Metals and trace elements Arsenic (speciated) Arsenobetaine/arsenocholine Arsenocholine EE - Benzene metabolites Biospecimen urine urine urine urine urine urine urine urine urine urine hair hair urine urine urine 6-79 6-79 S 6-79 6-79 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 12 Table 4: Laboratory Biospecimen Tests (continued) Theme Subject EE - Metals and trace elements (Cont'd) Arsenic (V) acid Arsenous (III) acid Dimethylarsinic acid Monomethylarsonic acid Arsenic (total) Arsenic Arsenic (total) Baryum Beryllium Bismuth Boron Cadmium Cadmium Cadmium Cesium Chromium Cobalt Cobalt Cobalt Copper Copper Copper Fluoride Lead Lead Lead Lithium Manganese Manganese Manganese Biospecimen urine urine urine urine blood hair urine hair hair hair urine blood hair urine urine hair blood hair urine blood hair urine urine blood hair urine hair blood hair urine Cycle 1 2007-2009 Cycle 2 2009-2011 Cycle 3 2012-2013 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S Cycle 4 Cycle 5 2014-2015 2016-2017 Age (years) 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S Cycle 6 2018-2019 Cycle 7 2020-2021 Cycle 8 2022-2023 3-79 3-79 3-79 3-79 3-79 S 3-79 S 3-79 S 3-79 S 6-79 6-79 20-59 20-59 20-59 20-59 20-59 3-79 S 3-79 20-59 3-79 S 20-59 20-59 20-59 3-79 S 3-79 20-59 3-79 S 20-59 20-59 20-59 20-59 20-59 20-59 3-79 20-59 3-79 20-59 20-59 20-59 20-59 20-59 3-79 6-79 3-79 6-79 3-79 3-79 3-79 3-79 3-79 6-79 6-79 3-79 3-79 6-79 3-79 3-79 S 3-79 6-79 3-79 6-79 6-79 3-79 S 3-79 3-79 S 3-79 3-79 3-79 13 Table 4: Laboratory Biospecimen Tests (continued) Theme Subject Mercury Inorganic Inorganic Methyl Total Molybdenum Molybdenum Molybdenum Nickel Nickel Nickel RBC chromium EE - Metals and trace elements (Cont'd) Selenium Selenium Selenium Silver Silver Silver Strontium Tellurium Thallium Thallium Thorium Tin Tungsten Tungsten Uranium Uranium Uranium Vanadium Vanadium Biospecimen blood urine blood blood blood hair urine blood hair urine blood blood urine hair blood hair urine hair hair urine hair hair hair hair urine blood hair urine hair urine Cycle 1 2007-2009 Cycle 2 2009-2011 6-79 S 6-79 6-79 6-79 3-79 3-79 6-79 6-79 3-79 3-79 6-79 6-79 6-79 Cycle 3 2012-2013 3-79 20-79 S 3-79 Cycle 4 Cycle 5 2014-2015 2016-2017 Age (years) 3-79 20-79 S 3-79 Cycle 6 2018-2019 Cycle 7 2020-2021 Cycle 8 2022-2023 3-19 S 3-79 3-19 S 3-79 3-79 3-79 20-59 20-59 20-59 20-59 3-79 S 3-79 3-79 S 3-79 20-59 20-59 20-59 20-59 20-59 20-59 20-59 20-59 20-59 20-59 20-59 20-59 20-59 20-59 20-59 20-59 20-59 20-59 20-59 20-59 3-79 3-79 3-79 3-79 3-79 3-79 6-79 3-79 3-79 6-79 3-79 6-79 3-79 14 Table 4: Laboratory Biospecimen Tests (continued) Theme Subject EE - Metals and trace elements (Cont'd) Zinc Zinc Zinc Aldrin alpha-Chlordane gamma-Chlordane cis-Nonachlor trans-Nonachlor Oxychlordane beta-Hexachlorocyclohexane (ß-HCH) gamma-Hexachlorocyclohexane (γ-HCH) Hexachlorobenzene (HCB) Mirex p,p'-DDE p,p'-DDT Toxaphene parlar 26 Toxaphene parlar 50 Acephate Diethylphosphate (DEP) Diethylthiophosphate (DETP) Diethyldithiophosphate (DEDTP) Dimethylphosphate (DMP) Dimethylthiophosphate (DMTP) Dimethyldithiophosphate (DMDTP) Malathion dicarboxylic acid Methamidophos 3,5,6 Trichloro-2-pyridinol Butyl paraben Ethyl paraben Methyl paraben Propyl paraben EE Organochlorine pesticides EE Organophosphate insecticides EE - Parabens Biospecimen blood hair urine blood blood blood blood blood blood blood blood blood blood blood blood blood blood urine urine urine urine urine urine urine urine urine urine urine urine urine urine Cycle 1 2007-2009 Cycle 2 2009-2011 6-79 3-79 6-79 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 20-79 S 3-79 6-79 S 6-79 S 6-79 S 6-79 S 6-79 S 6-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S Cycle 3 2012-2013 Cycle 4 Cycle 5 2014-2015 2016-2017 Age (years) Cycle 6 2018-2019 20-59 20-59 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 Cycle 7 2020-2021 Cycle 8 2022-2023 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 15 Table 4: Laboratory Biospecimen Tests (continued) Cycle 2 2009-2011 Subject EE - Perfluoroakyl substances Perfluorobutane sulfonate (PFBS) Perfluorodecanoic acid (PFDA) Perfluorohexane sulfonate (PFHxS) Perfluorohexanoic acid (PFHxA) Perfluoro-n-butyric acid (PFBA) Perfluorononanoic acid (PFNA) Perfluorooctane sulfonate (PFOS) Perfluorooctanoic acid (PFOA) Perfluoroundecanoic acid (PFUDA) blood blood blood blood blood blood blood blood blood 2,4-Dichlorophenoxyacetic acid (2,4-D) urine 6-79 3-79 S Mono benzyl phthalate (MBzP) Mono-3-carboxypropyl phthalate (MCPP) urine urine 6-49 6-49 3-79 S 3-79 S Mono-3-hydroxy-n-butyl phthalate (3OH-MBP) urine Mono cyclohexyl phthalate (MCHP) Mono-(2-ethyl-5-hydroxyhexyl) phthalate (MEHHP) urine 6-49 urine Mono-(2-ethyl-5-oxohexyl) phthalate (MEOHP) Mono-2-ethylhexyl phthalate (MEHP) Mono ethyl phthalate (MEP) Mono-iso-butyl phthalate (MiBP) Mono-isononyl phthalate (MNP) Mono-n-butyl phthalate (MBP) Mono-n-octyl phthalate (MOP) Mono-methyl phthalate (MMP) Mono-carboxy-n -heptyl phthalate (MCHpP) Mono(2-ethyl-5-carboxypentyl) phthalate (MECPP) Mono(2-carboxymethylhexyl) phthalate (MCMHP) EE - Phenoxy Herbicide EE - Phthalate metabolites Biospecimen Cycle 1 2007-2009 Theme 20-79 20-79 20-79 12-79 S 12-79 S 12-79 S 12-79 S 12-79 S 12-79 S 12-79 S 12-79 S 12-79 S Cycle 3 2012-2013 Cycle 4 Cycle 5 2014-2015 2016-2017 Age (years) 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S Cycle 6 2018-2019 Cycle 8 2022-2023 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 6-49 3-79 S 3-79 S 3-79 S urine 6-49 3-79 S 3-79 S 3-79 S urine urine urine urine urine urine urine urine 6-49 6-49 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S urine 3-79 S 3-79 S urine 3-79 S 3-79 S 6-49 6-49 6-49 6-49 Cycle 7 2020-2021 16 Table 4: Laboratory Biospecimen Tests (continued) Theme EE - Phthalate metabolites (Cont'd) EE - Alternate plasticizers EE - Polyaromatic hydrocarbons Subject Mono(carboxyisooctyl) phthalate (MCIOP) Mono(oxoisononyl) phthalate (MOINP) Mono(hydroxyisononyl) phthalate (MHINP) Monocarboxyisononyl phthalate (MCiNP) Monoisodecyl phthalate (MIDP) Monooxoisodecyl phthalate (MOiDP) Monohydroxyisodecyl phthalate (MHiDP) Mono-isononyl-cyclohexane-1,2-dicarboxylate (MINCH) Cyclohexane-1,2-dicarboxylic acid (CHDA) Cyclohexane-1,2-dicarboxylic mono hydroxyisononyl ester (OH-MINCH) cyclohexane-1,2-dicarboxylic mono oxoisononyl ester (oxo-MINCH) Cyclohexane-1,2-diarboxylic mono carboxyisononyl ester(cx-MINCH) 2,2,4 trimethyl-1,3, pentanediol diisobutyrate (TXIB) 2,2,4-trimethyl-1,2-pentanediol (TMPD) 2,2,4-trimethyl-3-hydroxy valeric acid (HTMV) 1-mono(2-ethylhexyl)trimellitate (1-MEHTM) 2-mono(2-ethylhexyl)trimellitate (2-MEHTM) 4-mono(2-ethylhexyl)trimellitate (4-MEHTM) 1,2-di(2-ethylhexyl)trimellitate (1,2-DEHTM) 2,4-di(2-ethylhexyl)trimellitate (2,4-DEHTM) 1,4-di(2-ethylhexyl)trimellitate (1,4-DEHTM) Chrysenes 2-Hydroxychrysene 3-Hydroxychrysene 4-Hydroxychrysene 6-Hydroxychrysene Fluoranthene Biospecimen Cycle 1 2007-2009 Cycle 2 2009-2011 Cycle 3 2012-2013 urine urine urine urine urine urine urine Cycle 4 Cycle 5 2014-2015 2016-2017 Age (years) 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S Cycle 6 2018-2019 3-79 S 3-79 S urine 3-79 S 3-79 S urine 3-79 S 3-79 S urine 3-79 S 3-79 S urine 3-79 S 3-79 S urine 3-79 S 3-79 S urine urine urine urine urine urine urine urine 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S Cycle 8 2022-2023 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S urine urine urine urine urine Cycle 7 2020-2021 3-79 S 3-79 S 3-79 S 3-79 S 17 Table 4: Laboratory Biospecimen Tests (continued) Theme EE - Polyaromatic hydrocarbons (Cont'd) EE Polybrominated flame retardents EE Polychlorinated biphenyls (PCBs) EE - Pyrethroids (metabolites) Subject Cycle 2 2009-2011 Cycle 3 2012-2013 urine 3-79 S 3-79 S urine urine urine 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S urine urine 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S Biospecimen Cycle 1 2007-2009 Cycle 4 Cycle 5 2014-2015 2016-2017 Age (years) 3-79 S Cycle 6 2018-2019 3-Hydroxyfluoranthene Fluorenes 2-Hydroxyfluorene 3-Hydroxyfluorene 9-Hydroxyfluorene Napthalenes 1-Hydroxynaphthalene 2-Hydroxynaphthalene Phenanthrenes 1-Hydroxyphenanthrene 2-Hydroxyphenanthrene 3-Hydroxyphenanthrene 4-Hydroxyphenanthrene 9-Hydroxyphenanthrene Pyrene 3-Hydroxybenzo(a)pyrene 1-Hydroxypyrene Polybrominated biphenyls 153 (PBB 153) urine urine urine urine urine 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S urine urine blood 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 3-79 S 20-79 SP Polybrominated diphenyl ether (PBDE) 15, 17 blood 20-79 SP PBDE 25, 28, 33, 47, 99, 100, 153 Aroclor 1260 PCB 28, 52, 66, 74, 99, 101, 105, 118, PCB 128, 138, 146, 153, 156, 163, 167, 170 PCB 178, 180, 183, 187, 194, 201, 203, 206 Cis-3-(2,2-dibromovinyl)-2,2dimethylcyclopropane carboxylic acid (cisDBCA) blood blood blood blood blood 20-79 SP 20-79 S 20-79 S 20-79 S 20-79 S urine 6-79 3-79 S 3-79 S 3-79 S urine 6-79 3-79 S 3-79 S 3-79 S urine 6-79 3-79 S 3-79 S 3-79 S Cis-3-(2,2-dichlorovinyl)-2,2dimethylcyclopropane carboxylic acid (cisDCCA) 4-fluoro-3-phenoxybenzoic acid (4-F-3-PBA) Cycle 7 2020-2021 Cycle 8 2022-2023 18 Table 4: Laboratory Biospecimen Tests (continued) Theme Subject 3-phenoxybenzoic acid (3-PBA) trans-3-(2,2-dichlorovinyl)-2,2dimethylcyclopropane carboxylic acid (transDCCA) Nicotine and metabolites Anabasine Free cotinine Cotinine-n-glucuronide Total cotinine Nicotine (total) EE - Tobacco Nicotine-n-glucuronide Trans-3-Hydroxycotinine (total) Trans-3-Hydroxycotinine-glucuronide NNK metabolites (4-(methyl-nitrosamino)-1butanone) Free NNAL Total NNAL Atrazine mercapturate EE - Triazine Desethylatrazine herbicides Diaminochlorotriazine Common fuel pollutants (BTEX) Benzene Ethylbenzene m- & p-Xylenes o-Xylene Toluene EE - Volatile organic compounds Trihalomethanes Bromodichloromethane Dibromochloromethane Tribromomethane Trichloromethane Other EE - Pyrethroids (metabolites) (Cont'd) Biospecimen Cycle 1 2007-2009 Cycle 2 2009-2011 urine 6-79 3-79 S urine 6-79 3-79 S urine urine urine urine urine urine urine urine 12-79 S 6-79 12-79 S 12-79 S 12-79 S 12-79 S 12-79 S 12-79 S urine urine urine urine urine 12-79 S 12-79 S 3-79 Cycle 3 2012-2013 Cycle 4 Cycle 5 2014-2015 2016-2017 Age (years) 3-79 S Cycle 6 2018-2019 3-79 S 12-79 3-79 12-79 12-79 3-79 12-79 12-79 12-79 12-79 12-79 12-79 12-79 12-79 12-79 12-79 12-79 12-79 12-79 12-79 S 12-79 S 12-79 S 12-79 S 12-79 S 12-79 S 3-79 Cycle 8 2022-2023 3-79 S 3-79 S 12-79 3-79 12-79 Cycle 7 2020-2021 3-79 S 3-79 S 3-79 S blood blood blood blood blood 12-79 S 12-79 S 12-79 S 12-79 S 12-79 S 12-79 S 12-79 S 12-79 S 12-79 S 12-79 S 12-79 S 12-79 S 12-79 S 12-79 S 12-79 S 12-79 S 12-79 S 12-79 S 12-79 S 12-79 S blood blood blood blood 12-79 S 12-79 S 12-79 S 12-79 S 12-79 S 12-79 S 12-79 S 12-79 S 12-79 S 12-79 S 12-79 S 12-79 S 12-79 S 12-79 S 12-79 S 12-79 S 19 Table 4: Laboratory Biospecimen Tests (continued) Theme EE - Volatile organic compounds (Cont'd) EE - Other General characterization Infection markers Subject Biospecimen Styrene Alkanes Hexane Heptane Furans and dioxins Tetrahydrofuran 2,5-dimethylfuran 1,4-dioxane Chlorinated hydrocarbons 1,1,1,2-tetrachloroethylene 1,1,2-trichloroethylene 1,2-dichloroethane Hexachloroethane Chlorobenzene 1,2-dichlorobenzene 1,4-dichlorobenzene 1,2,3-trichloropropane Chloromethylbenzene Bisphenol A (BPA) Ethylene thiourea (ETU) ortho-phenylphenol (OPP) Pooled serum organohalogens Triclocarban Triclosan Creatinine Specific gravity Hepatitis A, B and C profile Hepatitis A virus antibody Hepatitis B virus core antibody Hepatitis B virus surface antibody blood blood blood blood Hepatitis B virus surface antigen blood Cycle 1 2007-2009 Cycle 2 2009-2011 Cycle 3 2012-2013 12-79 S Cycle 4 Cycle 5 2014-2015 2016-2017 Age (years) 12-79 S 12-79 S Cycle 6 2018-2019 12-79 12-79 12-79 12-79 blood blood blood 12-79 12-79 12-79 12-79 12-79 12-79 12-79 S 12-79 S 12-79 12-79 12-79 12-79 12-79 12-79 12-79 3-79 S 3-79 S 3-79 S 3-79 P 3-79 3-79 3-79 S 3-79 3-79 3-79 3-79 3-79 P 3-79 P 3-79 S 3-79 3-79 3-79 S 3-79 3-79 3-79 3-79 14-79 14-79 14-79 14-79 14-79 14-79 14-79 14-79 14-79 14-79 14-79 14-79 14-791 14-791 14-791 14-791 14-791 14-791 6-79 3-79 3-79 S 3-79 S 3-79 S 3-79 3-79 3-79 S 12-79 S 12-79 S 3-79 S 12-79 S 12-79 S 12-79 12-79 12-79 12-79 12-79 12-79 12-79 3-79 S 3-79 S 3-79 S 3-79 P 6-79 12-79 S 12-79 S Cycle 8 2022-2023 12-79 S blood blood blood blood blood blood blood blood blood blood blood urine urine urine blood urine urine urine urine Cycle 7 2020-2021 20 Table 4: Laboratory Biospecimen Tests (continued) Theme Infection markers (Cont'd) Kidney health Nutritional status Reproductive hormones Thyroid Status Subject Biospecimen Cycle 1 2007-2009 Cycle 2 2009-2011 Cycle 3 2012-2013 14-79 14-79 14-79 14-79 S Cycle 4 Cycle 5 2014-2015 2016-2017 Age (years) 14-79 14-79 S 14-59 Cycle 6 2018-2019 Cycle 7 2020-2021 Cycle 8 2022-2023 14-79 14-79 14-79 14-79 Hepatitis C virus antibody Hepatitis C RNA Chlamydia trachomatis Herpes simplex-2 Human Papillomavirus (HPV 6, 11, 13, 16, 18, 26, 30-35, 39, 40, 42-45, 51-54, 56-59, 61, 62, 66-74, 81-87, 89-91, 97) Toxoplasmosis Microalbumin Ferritin blood blood urine blood blood urine blood 6-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 Iodine (clinic) urine 6-79 3-79 3-79 3-79 2 2 3-79 3-79 14-59 14-59 urine Iodine (household) urine Sodium (hhld & clinic) Potassium (hhld & clinic) Parathyroid hormone Red blood cell folate Vitamin B12 Vitamin C (L-ascorbic acid) Vitamin D3 [(25-OH)] - plasma Vitamin D3 [(25-OH)] - serum Vitamin D3 [3-epi-25-OH] Vitamin D2 [25-OH] Estradiol (E2) Follicle-stimulating hormone (FSH) Luteinizing hormone (LH) Progesterone (P4) Testosterone Anti-thyroglobulin Anti-thyroid peroxidase Free thyroxine Thyroid stimulating hormone urine urine blood blood blood blood blood blood blood blood blood blood blood blood blood blood blood blood blood 14-59 14-59 F 3-79 3-39 2 6-79 6-79 3-79 3-79 3-79 6-79 3-79 3-79 3-79 6-79 S 3-79 3-79 3-79 3-79 6-79 6-79 F 6-79 F 6-79 F 6-79 M 3-79 3-79 3-79 3-79 6-79 6-79 F 6-79 F 6-79 F 6-79 M 3-79 3-79 3-79 3-79 3-39 2 3-39 3-79 3-79 6-79 S 3-79 3-79 3-39 3-79 3-79 6-79 S 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 3-79 21 Table 4: Laboratory Biospecimen Tests (continued) Theme Subject Biospecimen Cycle 1 2007-2009 Cycle 2 2009-2011 Cycle 3 2012-2013 Cycle 4 Cycle 5 2014-2015 2016-2017 Age (years) Cycle 6 2018-2019 Cycle 7 2020-2021 Cycle 8 2022-2023 M=Males; F=Females;S=Subsample; P=Pooled Serum; EE=Environmental exposure Lab test done on sample of respondents who tested positive for hepatitis B core antibody 1 2 For both household and clinic urine samples, specific demographic groups will be measured for iodine 22 Table 5: Laboratory Indoor Air Sample Tests1 Theme Subject Acetone a-Pinene Benzaldehyde Benzene Benzenepropanol Benzofuran Biphenyl Environmental exposure 1-Bromodecane Bromodichloromethane Tribromomethane 1-Bromooctane 1-Bromopropane 1-Butanol 2-Butanone 2-Butoxyethanol Butyl ester benzoic acid Camphene Carbon tetrachloride Chlorobenzene 1-Chlorododecane Trichloromethane Chloromethylbenzene 4-Chloro,3-methylphenol 3-Chloropropene Cyclohexane Cyclohexanol Cyclohexanone Decamethylcyclopentasiloxane Decamethyltetrasiloxane Decanal Cycle 1 2007-2009 Cycle 2 2009-2011 Cycle 3 2012-2013 a a a a a a a a a a Cycle 4 Cycle 5 2014-2015 2016-2017 Tested at the household level Cycle 6 2018-2019 Cycle 7 2020-2021 Cycle 8 2022-2023 a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a 23 Table 5: Laboratory Indoor Air Sample Tests1 (continued) Theme Subject Decane Dibromochloromethane 1,2-Dibromoethane 1,2-Dichlorobenzene 1,4-Dichlorobenzene 1,1-Dichloroethane 1,2-Dichloroethane 2,4-/2,5-dichlorotoluene 1,3-Dichloro-2-propanol 1,2-dichloropropane 2,3-dichloropropene 1,2-Dimethoxyethane Dimethoxymethane 1,2-Dimethoxy-4-(2-propenyl)benzene Environmental exposure (cont'd) Dimethyl ester pentanedioc acid 2,5-Dimethylfuran 1,4-Dioxane Dodecamethylcyclohexasiloxane Dodecamethylpentasiloxane Dodecane Ethanediol diacetate 1-Ethenylpyrrolidinone 2-(2-Ethoxyethoxy)ethanol 2-Ethoxyethyl acetate Ethylbenzene Ethyl ester benzoic acid 2-Ethyl-1-hexanol 2-Furancarboxaldehyde Heptanal Heptane Cycle 1 2007-2009 Cycle 2 2009-2011 Cycle 3 2012-2013 a a a a a a a a a a a a Cycle 4 Cycle 5 2014-2015 2016-2017 Tested at the household level Cycle 7 2020-2021 Cycle 8 2022-2023 a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a Cycle 6 2018-2019 a a a a a a a a a a a a a a a a 24 Table 5: Laboratory Indoor Air Sample Tests1 (continued) Theme Subject 1,1,2,3,4,4-Hexachloro-1,3-butadiene Hexachloroethane Hexamethyldisiloxane Hexanal Hexane 2-Hexanone Limonene 2-Methoxyethyl acetate 2-(2-Methoxyethoxy)ethanol 2-Methyl-1,3-butadiene Methyl ester benzoic acid Methyl ester hexanoic acid Environmental exposure (cont'd) 1-Methylethylbenzene 5-Methyl-2-hexanone 4-Methyl-2-pentanone 4-Methylpenten-2-one 2-Methyl-2-propanol 2-Methylpropyl ester benzoic acid 1-Methylpyrrolidinone Naphthalene Nitromethane 1-Nitropropane 2-Nitropropane 2-nitrotoluene Nonanal Nonane Nonanol Octamethylcyclotetrasiloxane Octamethyltrisiloxane Octanal Cycle 1 2007-2009 Cycle 2 2009-2011 a a a a a a a a a a a a a a a a a a a a a a a a a Cycle 3 2012-2013 Cycle 4 Cycle 5 2014-2015 2016-2017 Tested at the household level Cycle 6 2018-2019 Cycle 7 2020-2021 Cycle 8 2022-2023 a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a 25 Table 5: Laboratory Indoor Air Sample Tests1 (continued) Theme Subject Cycle 1 2007-2009 Cycle 2 2009-2011 Octane Octanol Pentachloroethane Pentane 1-Pentanol Pentanone 2-Pentanone Perchloroethylene Phenol 1-Propanol Environmental exposure (cont'd) 2-Propanol Quinoline Styrene 1,1,1,2-Tetrachloroethane Tetrahydrofuran Toluene 1,2,3-Trichlorobenzene 1,2,4-Trichlorobenzene 1,3,5-Trichlorobenzene 1,1,2-Trichloroethane Trichloroethylene 1,2,3-Trichloropropane 1,2,3-Trimethylbenzene 1,2,4-trimethylbenzene 1,3,5-Trimethylbenzene 3,5,5-Trimethyl-2-cyclohexen-1-one Undecane o-Xylene m,p-Xylene Cycle 3 2012-2013 Cycle 4 Cycle 5 2014-2015 2016-2017 Tested at the household level Cycle 6 2018-2019 Cycle 7 2020-2021 Cycle 8 2022-2023 a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a a 26 Table 5: Laboratory Indoor Air Sample Tests1 (continued) Theme 1 Subject Cycle 1 2007-2009 Cycle 2 2009-2011 Cycle 3 2012-2013 Cycle 4 Cycle 5 2014-2015 2016-2017 Tested at the household level Cycle 6 2018-2019 Cycle 7 2020-2021 Cycle 8 2022-2023 As part of cycles 2, 3, 4, 7 and 8, respondents deploy an indoor air sampler (IAS) in their household. The IAS is deployed for seven days directly following their visit to the mobile examination centre. The IAS is then sent to a laboratory where the air is analysed for the volatile organic compounds indicated. 27 Table 6: Laboratory Tap Water Sample Tests1 Theme Subject Cycle 1 2007-2009 Cycle 2 2009-2011 Cycle 3 2012-2013 Cycle 4 2014-2015 Cycle 5 2016-2017 Cycle 6 2018-2019 Cycle 7 2020-2021 Cycle 8 2022-2023 Tested at the household-level (subsample of households) Environmental exposure 1 Fluoride Volatile organic compounds Common fuel pollutants (BTEX) Benzene Ethylbenzene m- & p-Xylenes o-Xylene Toluene Total xylene Trihalomethanes Bromodichloromethane Dibromochloromethane Tribromomethane Trichloromethane a a a a a a a a a a a a a a a a a a a a a a As part of cycles 3 and 4, interviewers collect water samples from a subsample of respondent homes at the time of the household interview 28