This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike License. Your use of this material constitutes acceptance of that license and the conditions of use of materials on this site. Copyright 2011, The Johns Hopkins University and Richard H. Morrow. All rights reserved. Use of these materials permitted only in accordance with license rights granted. Materials provided “AS IS”; no representations or warranties provided. User assumes all responsibility for use, and all liability related thereto, and must independently review all materials for accuracy and efficacy. May contain materials owned by others. User is responsible for obtaining permissions for use from third parties as needed. Background and Development of Summary Measures of Population Health (SMPH) Richard H. Morrow, MD, MPH Johns Hopkins University Section A Development of a Summary Measure (Healthy Life) in Ghana for Use in Policy and Planning Approaches to Resource Allocation for Health The usual - Last year’s + The ideal - Benefit/cost—maximize health per dollar CENDES (Latin America)—multi-criteria decision analysis - Frequency - - - - - Seriousness Vulnerability Infectiousness Community awareness Age group Ghana Health Planning Unit—comprehensive combined unitary analysis; healthy life saved/unit expenditure 4 Health Situation in Ghana,1980 Independence in 1957, Kwame Nkrumah High priority accorded to health and impressive increases - 3X increase in doctors and nurses - 4X increase in hospital beds - 5X increase in per capita expenditure 5 Health Situation in Ghana,1980 But in the last 20 years - Infant mortality continued at 130 per thousand live births - - Maternal mortality at 140 per 100,000 live births Birthrate at nearly 50 per 1000 population 6 Health Situation in Ghana,1980 7 Health Planning Process Where we want to be? “There” Where we are? “Here” 8 Health Planning Process—Where We Are Need to know … A. Where we are: “Here” Health assessment Inventory of Health System resources Health-related programs (interventions) Community perspectives 9 Health Planning Process—Where We Are Need to know … A. Where we are: “Here” Health assessment - Demography, census, mapping Inventory of Health System resources Health-related programs (interventions) Community perspectives 10 Health Planning Process—Where We Are Need to know … A. Where we are: “Here” Health assessment - Demography, census, mapping - Descriptive epidemiology—morbidity, mortality Inventory of Health System resources Health-related programs (interventions) Community perspectives 11 Health Planning Process—Where We Are Need to know … A. Where we are: “Here” Health assessment - Demography, census, mapping - Descriptive epidemiology—morbidity, mortality Inventory of Health System resources - Human resources - Facilities - Finances Health-related programs (interventions) Community perspectives 12 Health Planning Process—Where We Are Need to know … A. Where we are: “Here” Health assessment - Demography, census, mapping - Descriptive epidemiology—morbidity, mortality Inventory of Health System resources - Human resources - Facilities - Finances Health-related programs (interventions) - Preventive - Treatment - Rehabilitative Community perspectives 13 Health Planning Process—Where We Want to Be Need to know … B. Where we want to be: “There” Explicit health policies in operational terms - Defined goals - Specific objectives - Time-limited targets 14 Health Planning Process—From Here to There Need to know … C. How to get from “Here” to “There” Deciding the right things to do Doing the right things in the right way 15 Health Planning Process—From Here to There Need to know … C. How to get from “Here” to “There” Deciding the right things to do - Health sector priorities —> health planning Doing the right things in the right way 16 Health Planning Process—From Here to There Need to know … C. How to get from “Here” to “There” Deciding the right things to do - Health sector priorities —> health planning Doing the right things in the right way - Quality management 17 Deciding the Right Things to Do: Health Sector Priorities Five steps 1. Impact of disease (burden of disease measure) Disability + Death —> All other consequences Loss of healthy life 2. Interventions effective against disease Healthy life gained 3. Costs of these interventions Unit costs 4. Work out “benefit”/cost ratios Healthy life per $ 5. Ensure fair distribution Full coverage 18 Measuring Disease Burden: Information Needs Disease specific 1. Incidence 2. Disability Case disability ratio (CDR) Extent of disability Duration of disability 3. Case fatality ratio (CFR) 4. Average age of onset (or distribution) 5. Average age at death (or distribution) Population specific 1. Expectation of life at these ages 2. Distribution according to S-E and vulnerable groups 19 Measure Healthy Life Lost and Gained 20 Measurement Components Mortality - CFR - Expectation of life at onset and at death Disability and its components - CDR - Extent of disability - Duration 21 Valuing Components Valuing future life as compared to present: Discounting Valuing a given duration of life: Different value for life lived at different ages? Valuing productivity: Economic and social Valuing equity in relation to efficiency 22 Measure Healthy Life Lost and Gained Intervention programs - Alternatives and packages: What are they? Prevention of factors that initiate disease process Treatment of an ongoing process Reduction of risk factors Rehabilitation—resurrection 23 Measure Healthy Life Lost and Gained Interventions—factors to assess - Efficacy of intervention under ideal setting (randomized trials, evidence-based reviews) - Coverage (% of target population that obtains the intervention; target population = all who should receive the intervention) These depend upon … - Quality management Provider competence (and performance) User understanding (and action) System factors, including education, communication, and transportation Therefore … - Community effectiveness = effectiveness of interventions as actually used X actual coverage - Results from interventions Changes in health status attributable to them 24 Measuring Healthy Life “Burden of disease” measures are not an end Must relate these to health program cost to assist in decisions concerning resource allocation and planning 25 Measuring Healthy Life Effectiveness of interventions as used - Efficacy X coverage X quality assurance Effects of interventions and their costs - Healthy life gained per dollar spent Ensure that distribution of gains is fair Priority interventions— THE RIGHT THING ! 26 Health Gaps Health gaps quantify the difference between the actual health of the population and some stated norm or goal for population health 27 Expectation of Life 28 Different Patterns of Healthy Life Lost in Individuals 29 Different Patterns of Healthy Life Lost in Individuals 30 Different Patterns of Healthy Life Lost in Individuals 31 Variables for HeaLY Estimation I Incidence rate per 1,000 population per year Per 1,000 per year Ao Average age at onset Years Af Average age at death Years E(Ao) Expectation of life at age of onset Years E(Af) Expectation of life at age of death Years 32 Variables for HeaLY Estimation CFR Case fatality ratio: proportion of those developing the disease who die from the disease 0.00–1.00 CDR Case disability ratio: proportion of those developing the disease who have disability from the disease 0.00–1.00 De Extent of disability (from none to complete disability equivalent to death) 0.00–1.00 Dt Average duration of disability for those disabled by the disease; a composite of temporary and permanent disability based on the proportion of cases in each category Years 33 HeaLYs Lost per 1,000 Population per Year I * {[CFR * {E(Ao) - [Af-Ao]}] + [CDR*De*Dt]} Expressed as HeaLYs per 1,000 pop per year 34 Diseases of Ghana Ranked in Order of Healthy Days Lost Ghana Health Assessment Project Team (1981). A quantitative method of assessing the health impact of different diseases in less developed countries. International Journal of Epidemiology. 10: 73-80 Effects Interventions May Have on HLL Sign ΔI ΔCFR ΔAf ΔCDR Explanation Reduction factor for Incidence among those covered by the intervention Reduction factor for Case Fatality Ratio among those covered by the intervention Extension factor for Age at death Reduction factor for Case Disability Ratio among those covered by the intervention ΔDe Reduction factor for Extent of disability among those covered by the intervention ΔDt Reduction factor for Duration of disability among those covered by the intervention PC1 Proportion of Population Covered by present health system interventions PCn Proportion of Population Covered by proposed health system interventions ΔXn Reduction factor for X among those covered by proposed YHLG Years of Healthy Life Gained per thousand per 1,000 population per year = ΔI * [(CFR * (E(Ao) – (Af- Ao)) + (CDR * De* Dt)] 36 The 5th Step The dollar value of healthy life - Productivity: average or marginal wage - - Human capital approach WTP: review of legislative decisions concerning safety regulations—$50,000 to billions per life - - Jeffrey Sachs: Two times the per capita gross national income Cost-effectiveness analysis: λ, the decision maker’s willingness to pay for the last intervention on the list of a league table 37 The 5th Step The dollar value of healthy life - Productivity: average or marginal wage - - Human capital approach WTP: review of legislative decisions concerning safety regulations—$50,000 to billions per life - - Jeffrey Sachs: Two times the per capita gross national income Cost-effectiveness analysis: λ, the decision maker’s willingness to pay for the last intervention on the list of a league table 38