ABIO 550W IMMUNOLOGY Syllabus Spring 2012 Instructor: Office: Telephone: Lecture: Dr. William H. Jackson SBDG 201A 641-3601 TTh, 9:25AM – 10:40AM in SBDG 200 Dr. William Jackson Office Hours: Email: Text: Supplement: Credit: By appointment billj@usca.edu Kuby Immunology, 6th Ed. by Goldsby, Kindt, and Osborne Writing Papers in the Biological Sciences., 5th Edition by McMillan Three semester hours Course Description: A study of immunological principles and concepts. Three lecture hours per week. Course Objectives: This course will introduce the student to the underlying principles of immunology. Its primary emphasis will be on the cellular and non-cellular components of the human immune system and the ways in which these components interact to provide immunity. Upon completion of this course students will be expected to 1. Describe the major divisions of the immune system; 2. Describe humoral immunity and cell-mediated immunity; 3. Compare and contrast innate and acquired immunity; 4. Discuss the role of immune cells, their function with regard to cell signaling, and hematopoiesis; 5. Discuss the immune response to specific pathogens; and 6. Describe the nature of self and non-self; Attendance Policy: An “F” may be assigned for absences in excess of 25% of regularly scheduled class meetings. Absences, neither excused nor unexcused, absolve the student from meeting class assignments. Exam make-ups will only be allowed for documented, excusable reasons. Quizzes cannot be made up. Disability Statement: If you have a physical, psychological, and/or learning disability, which might affect your performance in class, please contact the Office of Disability Services, 134 B&E (803) 641-3609, as soon as possible. The Disability Services Office will determine appropriate accommodations based on medical documentation. Policy for Portable Electronic Devices: The use of any portable electronic devices, including cell phones, pagers, MP3 players, iPods, etc., during class is not allowed for any reason unless prior approval has been given to a student from the instructor or unless required for the course. If you are planning to have any of these devices in class, they must be turned off and stowed away for the duration of the class period. If you use a portable electronic device during a test, quiz, or other assessment, you are eligible to receive a failing grade on that assignment. Methods of Presentation and Evaluation: Information will be presented through lectures and class discussion using appropriate visual aids. Writing assignments will be used to extend the lecture material. There will be three 1-hour exams, a comprehensive final exam, and weekly quizzes that will generally cover the previous 1-2 week’s material. Writing assignments will include reviews of the primary literature and a research paper based on a question in immunology. WI Designation: ABIO 550 is designated a writing intensive course (ABIO 550W). The goal is not so much to teach writing, but to use writing as a learning tool. During this course we will answer the following questions: How do you ask a good question? How do you develop a thesis? How do you create a well-crafted scientific paper? Writing Assignments: Below is a brief overview of the writing assignments you will be responsible for during the semester. More complete descriptions and tasks will be provided separately. Written products will be evaluated based on one of two rubrics that will be provided with each assignment. Multiple revisions will be encouraged during the writing process, and will be based on both peer reviews and conferences with the instructor. Research paper. Your research paper will be on a question or problem of your choosing in immunology. Revisions will be allowed (and expected) based on peer reviews and conferences with the instructor. Research summaries. You will be assigned seven primary research articles from your research paper’s bibliography to summarize. Methods of Presentation and Evaluation: Information will be presented through lectures and class discussion using appropriate visual aids. Final grades will be based on the following: -1- ABIO 550 IMMUNOLOGY syllabus Description Three one-hour exams Research Paper Final Exam Weekly quizzes Reviews Participation Points 450 150 100 100 140 60 Spring 2010 Comments 150 points each 150 points Comprehensive Generally covering the previous 1 – 2 week’s material Review of assigned readings (seven, 20points each) Class participation (4 points per week) Letter grades will be assigned as follows: A>900; B>800; C>650; D>550; F<550. You will be expected to endorse the USCA HONOR PLEDGE on every assignment: 'On my honor as a University of South Carolina Aiken student, I have neither given nor received any unauthorized aid on this assignment/examination. To the best of my knowledge, I am not in violation of academic honesty'. TENTATIVE LECTURE SCHEDULE DATE Jan 10 Jan 12 Jan 17 Jan 19 Jan 24 Jan 26 Jan 31 Feb 2 Feb 7 Feb 9 Feb 14 Feb 16 Feb 21 Feb 23 Feb 28 Mar 1 Mar 6 Mar 8 Mar 13 Mar 15 Mar 20 Mar 22 Mar 27 Mar 29 Apr 3 Apr 5 Apr 10 Apr 12 Apr 17 Apr 19 Apr 26 WEEK 1 TOPIC Overview of the Immune System CHAPTER 1 2 Cells and Organs of the Immune System 2 3 Antigens and Antibodies EXAM I Antigens and Antibodies 4 Antigens and Antibodies Organization and Expression of Immunoglobulin Genes Organization and Expression of Immunoglobulin Genes 4 5 5 5 8 8 9 Organization and Expression of Immunoglobulin Genes Major Histocompatibility Complex Major Histocompatibility Complex EXAM II Spring Break - No classes 10 T-Cell Receptor 9 11 Hypersensitivity Reactions 15 12 Tolerance and Autoimmunity 16 13 Immune Response to Infectious Disease 18 14 EXAM III AIDS and Other Immunodeficiencies AIDS and Other Immunodeficiencies 20 20 FINAL EXAM, 8:00 AM in SBDG 200 Comp 4 5 6 7 8 15 -2- 4