ABIO 550 IMMUNOLOGY Syllabus
Spring 2010
Instructor:
Office:
Telephone:
Lecture:
Dr. William H. Jackson
SBDG 201A
641-3601
TTh, 9:25AM – 10:40AM in
SBDG 200
Dr. William Jackson
Office Hours:
Email:
Text:
Supplement:
Credit:
By appointment
billj@usca.edu
Kuby Immunology, 6th Ed. by Goldsby, Kindt,
and Osborne
Writing Papers in the Biological Sciences., 4th
Edition by McMillan
Three semester hours
Course Description: A study of immunological principles and concepts. Three lecture hours per week.
Course Objectives: This course will introduce the student to the underlying principles of immunology. Its primary emphasis
will be on the cellular and non-cellular components of the human immune system and the ways in which these components
interact to provide immunity. Upon completion of this course students will be expected to
1. Describe the major divisions of the immune system;
2. Describe humoral immunity and cell-mediated immunity;
3. Compare and contrast innate and acquired immunity;
4. Discuss the role of immune cells, their function with regard to cell signaling, and hematopoiesis;
5. Discuss the immune response to specific pathogens; and
6. Describe the nature of self and non-self;
Attendance Policy: The instructor may impose a penalty for absences in excess of 25% of regularly scheduled class meetings
by assigning an “F” for the course. Absences, neither excused nor unexcused, absolve the student from meeting class
assignments. Exam make-ups will only be allowed for a documented, excusable reason. Weekly quizzes cannot be made up.
Disability Statement: If you have a physical, psychological, and/or learning disability, which might affect your performance
in class, please contact the Office of Disability Services, 126A B&E (803) 641-3609, as soon as possible. The Disability
Services Office will determine appropriate accommodations based on medical documentation.
Classroom Behavior: It is the instructor’s right to remove from the classroom any student who disrupts or disturbs the
proceeding of the class. Disruption of the class includes but is not limited to the use of any portable electronic devices,
including cell phones, MP3 players; iPods, etc. unless prior approval has been given to a student or unless required for the
course. In extreme cases the faculty member can request assistance from University Police. If the student who has been
ejected causes similar disturbances in subsequent meetings of the class, he/she may be denied admittance to the class for the
remainder of the semester and assigned a grade of F.
Methods of Presentation and Evaluation: Information will be presented through lectures and class discussion using
appropriate visual aids. Final grades will be based on the following:
Description
Three one-hour exams
Review and Poster
Final Exam
Weekly quizzes
Readings
Points
450
200
150
100
100
Comments
150 points each
200 points (paper = 150 points; poster = 50 points)
Comprehensive
Generally covering the previous 1 – 2 week’s material
Assigned readings (five, 20points each)
Letter grades will be assigned as follows: A>900; B>800; C>650; D>550; F<550.
Review and Poster. Twenty percent of your final grade will be from a literature review of an assigned topic in immunology.
Each topic will be based on a human health condition associated with abnormal immunological functioning. The student will
conduct a literature search and prepare a review of their topic. The paper should provide information on all immunological
aspects of the disease as described in the current literature. All figures must be referred to within the body of the text and must
be placed on individual pages in an appendix following the Literature cited section. The paper must be double-spaced, at least
eight pages in length (excluding figures), and include in-text citations and a literature cited section. It should be written in 12
point Times New Roman font and have 1 inch margins. Figures, if included, should be numbered, titled, and referred to in a
consistent manner (e.g., Fig. 1, Fig. 2, etc.). A description of how to write a research paper can be found in chapters 4-8 in your
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ABIO 550 IMMUNOLOGY syllabus
Spring 2010
test, “Writing Papers in the Biological Sciences.” References must be cited in the text using CSE format. Citation tools can be
found at the USCA library website: http://library.usca.edu/index.php/Main/CitationStyleGuidesAmpCitationTools.
A minimum of 15 primary literature sources must be used for the paper. Although texts are not considered primary literature,
relevant texts are acceptable (one text for every ten sources). Encyclopedias, Wikipedia, and web sites are NOT considered
primary literature and must not be included as references. Web site exceptions are the Centers for Disease Control (CDC) and
the National Institutes of Health (NIH). However, if these sites are used, they cannot be counted toward the 15 source
minimum. Most of your sources can be found at journal databases such as Medline through the National Library of Medicine
(http://www.nlm.nih.gov). Figures obtained from a web site and used in the paper are acceptable and should be credited in the
figure legend. The final paper will be submitted electronically through the library’s TURNITIN database.
Due dates (review): Jan 22 (completed bibliography); Mar 16 (first draft, 7 page minimum); Apr 16 (completed paper).
Due dates (reports): Jan 29, Feb 5, Feb 12, Feb 19, Feb 26
Due dates (poster): Apr 19 (completed poster); Apr 22 (poster session)
TENTATIVE LECTURE SCHEDULE
DATE
Jan 12
Jan 14
Jan 19
Jan 21
Jan 26
Jan 28
Feb 2
Feb 4
Feb 9
Feb 11
Feb 16
Feb 18
Feb 23
Feb 25
Mar 2
Mar 4
Mar 9
Mar 11
Mar 16
Mar 18
Mar 23
Mar 25
Mar 30
Apr 1
Apr 6
Apr 8
Apr 13
Apr 15
Apr 20
Apr 22
Apr 29
WEEK
1
TOPIC
Overview of the Immune System
CHAPTER
1
2
Cells and Organs of the Immune System
2
3
Antigens and Antibodies
EXAM I
Antigens and Antibodies
4
Antigens and Antibodies
Organization and Expression of Immunoglobulin Genes
Organization and Expression of Immunoglobulin Genes
4
5
5
5
8
8
9
Organization and Expression of Immunoglobulin Genes
Major Histocompatibility Complex
Major Histocompatibility Complex
EXAM II
Spring Break - No classes
10
T-Cell Receptor
9
11
Hypersensitivity Reactions
15
12
Tolerance and Autoimmunity
16
13
Immune Response to Infectious Disease
18
14
EXAM III
AIDS and Other Immunodeficiencies
AIDS and Other Immunodeficiencies
Poster Presentation
FINAL EXAM, 8:00 AM in SBDG 200
4
5
6
7
8
15
4
20
20
Comp
You will be expected to endorse the USCA HONOR PLEDGE on every assignment: 'On my honor as a University of South Carolina
Aiken student, I have neither given nor received any unauthorized aid on this assignment/examination. To the best of my knowledge, I
am not in violation of academic honesty'.
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