BIOL 550 IMMUNOLOGY Syllabus Instructor: Office: Telephone: Lecture: Dr. William H. Jackson SBDG 201A 641-3601 TTh, 9:25AM – 10:40AM in SBDG 200 Spring 2016 Office Hours: Email: Text: Supplement: Credit: By appointment billj@usca.edu Kuby Immunology, 7th Ed. by Owen, Punt, and Stranford Writing Papers in the Biological Sciences, 5th Edition by McMillan Three semester hours Course Description: A study of immunological principles and concepts. Writing Intensive. Three lecture hours per week. Course Objectives: This course will introduce the student to the underlying principles of immunology. Its primary emphasis will be on the cellular and non-cellular components of the human immune system and the ways in which these components interact to provide immunity. Upon completion of this course students will be expected to 1. Describe the major divisions of the immune system; 2. Describe humoral immunity and cell-mediated immunity; 3. Compare and contrast innate and acquired immunity; 4. Discuss the role of immune cells, their function with regard to cell signaling, and hematopoiesis; 5. Discuss the immune response to specific pathogens; and 6. Describe the nature of self and non-self; Attendance Policy: An “F” may be assigned for absences in excess of 25% (seven lectures) of regularly scheduled class meetings. Absences, neither excused nor unexcused, absolve the student from meeting class assignments. Exam make-ups will only be allowed for documented, excusable reasons. Quizzes cannot be made up. Disability Statement: If you have a physical, psychological, and/or learning disability, which might affect your performance in class, please contact the Office of Disability Services, 134 B&E (803) 641-3609, as soon as possible. The Disability Services Office will determine appropriate accommodations based on medical documentation. Policy for Portable Electronic Devices: The use of any portable electronic devices, including cell phones, pagers, MP3 players, iPods, etc., during class is not allowed for any reason unless prior approval has been given to a student from the instructor or unless required for the course. If you are planning to have any of these devices in class, they must be turned off and stowed away for the duration of the class period. If you use a portable electronic device during a test, quiz, or other assessment, you are eligible to receive a failing grade on that assignment. Methods of Presentation and Evaluation: Information will be presented through lectures and class discussion using appropriate visual aids. Writing assignments will be used to extend the lecture material. There will be three 1-hour exams, a comprehensive final exam, and weekly quizzes that will generally cover the previous 1-2 week’s material. Writing assignments will include reviews of the primary literature and a research paper based on a question in immunology. WI Designation: Immunology is designated a writing intensive course. The goal is not so much to teach writing, but to use writing as a learning tool. During this course we will answer the following questions: How do you ask a good question? How do you develop a thesis? How do you create a well-crafted scientific paper? Writing Assignments: Below is a brief overview of the writing assignments you will be responsible for during the semester. More complete descriptions and tasks will be provided separately. Written products will be evaluated based on one of two rubrics that will be provided with each assignment. Revisions will be encouraged during the writing process, and will be based on both peer reviews and conferences with the instructor. Research paper. Your research paper will be on a question or problem of your choosing in immunology. Revisions will be allowed (and expected) based on peer reviews and conferences with the instructor. Research summaries. Based upon your particular immunological question, you will identify, read, and summarize seven primary research articles, which will subsequently make up a portion of your research paper’s bibliography. -1- BIOL 550 IMMUNOLOGY Syllabus Spring 2016 Methods of Presentation and Evaluation: Information will be presented through lectures and class discussion using appropriate visual aids. Final grades will be based on the following: Description Three one-hour exams Research Paper Final Exam Weekly quizzes Reviews Participation Points 300 150 100 100 140 60 Comments 100 points each Topic in Immunology Comprehensive From the previous 1-2 week’s material, 10 points each Review of assigned readings (20points each) Class participation (2 points per day) Letter grade assignment: A>90%; B+>85%; B>80%; C+>75%; C>60%; D+>55%; D>50%; F<50%. You will be expected to endorse the USCA HONOR PLEDGE on every assignment: 'On my honor as a University of South Carolina Aiken student, I have neither given nor received any unauthorized aid on this assignment/examination. To the best of my knowledge, I am not in violation of academic honesty'. TENTATIVE LECTURE SCHEDULE DATE Jan 12 Jan 14 Jan 19 Jan 21 Jan 26 Jan 28 Feb 2 Feb 4 Feb 9 Feb 11 Feb 16 Feb 18 Feb 23 Feb 25 Mar 1 Mar 3 Mar 8 Mar 10 Mar 15 Mar 17 Mar 22 Mar 24 Mar 29 Mar 31 Apr 5 Apr 7 Apr 12 Apr 14 Apr 19 Apr 21 May 3 WEEK 1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 TOPIC Overview of the Immune System Overview of the Immune System Cells, Organs, and Microenvironments of the Immune System Cells, Organs, and Microenvironments of the Immune System Cells, Organs, and Microenvironments of the Immune System EXAM I Receptors and Signaling: B and T-Cell Receptors Receptors and Signaling: B and T-Cell Receptors Receptors and Signaling: B and T-Cell Receptors Innate Immunity Innate Immunity Innate Immunity Organization and Expression of Lymphocyte Receptor Genes Organization and Expression of Lymphocyte Receptor Genes Organization and Expression of Lymphocyte Receptor Genes EXAM II Spring Break - No classes Spring Break - No classes The Major Histocompatibility Complex and Antigen Presentation The Major Histocompatibility Complex and Antigen Presentation The Major Histocompatibility Complex and Antigen Presentation Allergies, Hypersensitivities, and Chronic Inflammation Allergies, Hypersensitivities, and Chronic Inflammation Allergies, Hypersensitivities, and Chronic Inflammation Infectious Disease and Vaccines Infectious Disease and Vaccines Infectious Disease and Vaccines EXAM III Experimental Systems and Methods Experimental Systems and Methods FINAL EXAM, 8:00 AM in SBDG 200 -2- CHAPTER 1 1 2 2 2 3 3 3 5 5 5 7 7 7 8 8 8 15 15 15 17 17 17 20 20 Comp