Chapter 14 Microevolution in Modern Human Populations Human Populations Population Genetics Evolution in Action: Modern Human Populations Human Polymorphisms Human Bicultural Evolution Population Genetics Once a population is identified, can determine if evolutionary forces are operating on the population. Measure allele frequencies for specific traits and compare them with the Hardy-Weinberg model. Hardy-Weinberg Equilibrium Evolution is not taking place if: 1. Population is infinitely large. 2. No mutation. 3. No gene flow. 4. Natural selection is not operating. 5. Mating is random. Factors that Initiate Changes in Allele Frequencies 1. 2. 3. 4. Produce new variation (mutation). Redistribute variation through gene flow. Redistribute variation through genetic drift. Select "advantageous" allele combinations that promote reproductive success (natural selection). Human Biocultural Evolution Polymorphisms ABO Blood Group system Rh system MN blood group Human Biocultural Evolution Examples of the interaction of human cultural environments and biology: Sickle cell disease Lactose intolerance