S7L2. Students will describe the structure and function of cells, tissues, organs, and organ systems. A. Explain that cells take in nutrients in order to grow and divide and to make needed materials. B. Relate cell structures (cell membrane, nucleus, cytoplasm, chloroplasts, mitochondria) to basic cell functions. C. Explain that cells are organized into tissues, tissues into organs, organs into systems, and systems into organisms. D. Explain that tissues, organs, and organ systems serve the needs cells have for oxygen, food, and waste removal. Biochemistry • Study of chemical composition and reactions occurring in living matter • Inorganic Compounds • Do not contain carbon • Exceptions - CO2, CO, bicarbonates • Water is the most abundant and important inorganic material, making up 60% - 80% of all cells and 2/3 of body weight Organic Compounds • Contain the element carbon and hydrogen • Carbon is found in things that are or once were living. • Carbon atoms share electrons to form covalent bonds. Organic Compounds • Organic compounds are composed of hundreds to thousands of individual molecules. – The single molecules in a polymer are called monomers. Organic Compounds • The long molecules formed by repeating patterns of monomers are called polymers. Functional Groups • A functional group is a group of atoms that characterize the structure of a family of organic compounds. • Functional groups determine many of the properties of organic compounds. • 3 Types to Know: Amino (NH2), Carboxyl (COOH), Hydroxyl (OH). Macromolecules • 4 Types of Organic Compounds or macromolecules: carbohydrates, lipids, proteins, and nucleic acids. – Essential to maintaining life processes: cell function, storage, energy, homeostasis and genetic information. Carbohydrates • Make up sugars and starches • Contain a hydroxyl (OH) group • Contain atoms of carbon, hydrogen, and oxygen. • Provide energy to the cells. • Dissolve in water (hydrophilic) Types of Carbohydrates • Carbohydrates are classified according to size. • One sugar is a monosaccharide (monomer). • Two sugars make a disaccharide. • Many sugar molecules linked together form a polysaccharide (polymer). Monosaccharide Milk Sugar Fruit Sugar Disaccharide Maltose is two glucose molecules; forms in digestive tract of humans during starch digestion. Polysaccharide Starch is straight chain of glucose molecules with few side branches. Lipids • The three types of lipids are fats, oils, and waxes. • Contain carbon, hydrogen, and oxygen • Typically contain two monomers – glycerol and fatty acids • Glycerol contains the hydroxyl (OH) group. • Fatty acids contain the carboxyl (COOH) group. Functions of Lipids • Lipids store energy for later use by the body. • Lipids also serve as padding and protection for the body. • Lipids do not dissolve in water (hydrophobic), but may contain parts that can dissolve in water. Structure of a Lipid • Dissolves in water (hydrophilic) • Does not dissolve in water (hydrophobic) Phospholipid • Found in cell membranes – Head is the phosphate group. • Hydrophilic – Tails are the fatty acids. • Hydrophobic Fatty Acids • Long chains of carbon atoms with attached hydrogen atoms (hydrocarbons) • Saturated fats contain only single bonds between the carbon atoms. • Unsaturated fats contain one or more double or triple bonds between the carbon atoms. Proteins • Proteins are the building materials for the body. – Hair, skin, muscles, and organs are made mostly of proteins. • Composed of carbon, hydrogen, nitrogen, oxygen, and in some cases sulfur. • Contain amine (NH2) and carboxyl (COOH) groups Function of Proteins • The building blocks of proteins are amino acids (monomers). • Serve as enzymes which control rate of reactions and regulate cell processes. • Amino acids are connected by a special type of bond called a peptide bond. • Amino acid chains are called polypeptides. • A protein contains one or more polypeptide chains. Amino Acids Types of Proteins • There are two types of proteins – fibrous and globular. • Fibrous protein (found in skin, tendons, bones, and muscles) does not dissolve in water (hydrophobic). • Globular protein (found in enzymes, some hormones, and hemoglobin) can dissolve in water (hydrophilic). Fibrous Proteins • Keratins are a family of fibrous structural proteins; tough and insoluble, they form the hard but nonmineralized structures found in reptiles, birds, amphibians and mammals. Globular Proteins • Enzymes are proteins that catalyze (i.e. accelerate) chemical reactions. • Almost all processes in a biological cell need enzymes in order to occur at significant rates. Nucleic Acids DNA Very large organic molecules made of carbon, oxygen, hydrogen, nitrogen, and phosphorus. Function: – genetic material • stores information – genes – blueprint for building proteins » DNA RNA proteins • transfers information – blueprint for new cells – blueprint for next generation proteins Nucleic Acids • Examples: – RNA (ribonucleic acid) • single helix – DNA (deoxyribonucleic acid) • double helix • Structure: – monomers = nucleotides DNA RNA S7L2. Students will describe the structure and function of cells, tissues, organs, and organ systems. A. Explain that cells take in nutrients in order to grow and divide and to make needed materials. B. Relate cell structures (cell membrane, nucleus, cytoplasm, chloroplasts, mitochondria) to basic cell functions. C. Explain that cells are organized into tissues, tissues into organs, organs into systems, and systems into organisms. D. Explain that tissues, organs, and organ systems serve the needs cells have for oxygen, food, and waste removal. Cell History The History • Hans and Zacharias Janssen of Holland in the 1590’s created the “first” compound microscope • Anthony van Leeuwenhoek and Robert Hooke made improvements by working on the lenses. Anthony van Leeuwenhoek 1632-1723 He observed pond water, and he discovered animal-like protists that he called animalcules. Hooke Microscope Robert Hooke 1635-1703 He looked at cork plants and called the tiny structures he saw “CELLS”. Picture of early microscope and first drawings of cells by Robert Hooke. How a Microscope Works Convex Lenses are curved glass used to make microscopes (and glasses etc.) Convex Lenses bend light and focus it in one spot. How a Microscope Works Ocular Lens (Magnifies Image) Objective Lens (Gathers Light, Magnifies And Focuses Image Inside Body Tube) Body Tube (Image Focuses) Bending Light: The objective (bottom) convex lens magnifies and focuses (bends) the image inside the body tube and the ocular convex (top) lens of a microscope magnifies it again. Magnification • To determine your magnification…you just multiply the ocular lens by the objective lens • Ocular lens 10x Objective 40x: 10 x 40 = 400 So the object is magnified 400 times “larger” Objective Lens have their magnification written on them. Ocular lenses usually magnifies by 10x Simple Microscope • Similar to a magnifying glass and has only one lense. Compound Microscope • Lets light pass through an object and then through two or more lenses. Stereoscopic Microscope • Gives a three dimensional view of an object. (Examples: insects and leaves) Electron Microscope • Uses a magnetic field to bend beams of electrons; instead of using lenses to bend beams of light. Eyepiece Body Tube Revolving Nosepiece Arm Objective Lens Stage Clips Diaphragm Light Stage Coarse Focus Fine Focus Base Cell Theory Principles of Cell Theory • All living things are made of cells • Smallest living unit of structure and function of all organisms is the cell • All cells arise from preexisting cells (this principle discarded the idea of spontaneous generation) • Schleiden and Schwann used the work of Virchow and improved the cell theory. Cells are created from pre-existing cells! All plants are made of cells! All animals are made of cells! Principles of Cell Theory • All living things are made of cells • Smallest living unit of structure and function of all organisms is the cell • All cells arise from preexisting cells (this principle discarded the idea of spontaneous generation) S7L2. Students will describe the structure and function of cells, tissues, organs, and organ systems. A. Explain that cells take in nutrients in order to grow and divide and to make needed materials. B. Relate cell structures (cell membrane, nucleus, cytoplasm, chloroplasts, mitochondria) to basic cell functions. C. Explain that cells are organized into tissues, tissues into organs, organs into systems, and systems into organisms. D. Explain that tissues, organs, and organ systems serve the needs cells have for oxygen, food, and waste removal. Cell Structures and Functions Definition of Cell A cell is the smallest unit that is capable of performing life functions. Cell Size and Shape Cells Have Large Surface Area-to-Volume Ratio Characteristics of All Cells • A surrounding membrane • Cytoplasm – cell contents in thick fluid • DNA Two Types of Cells •Prokaryotic cells •Eukaryotic cells Prokaryotic Cells • First cell type on earth • Cell type of Bacteria and Archaea Prokaryotic Cell • Do not have internal structures surrounded by membranes • Few internal structures • All are onecelled organisms, Bacteria Prokaryotic Cells • No membrane bound nucleus • Nucleoid = region of DNA concentration Eukaryotic Cell • • • • Have membrane-bound internal structures called Organelles Can be unicellular or multicellular Protists, fungi, plants, and animals Much larger and more complex than prokaryotic cells Animal Plant Representative Animal Cell Representative Plant Cell Cell Structures and Functions Surrounding the Cell Cell Membrane Cell Wall Plasma Cell Membrane • Contains cell contents • Double layer of phospholipids & proteins • Membrane covering around all cells that controls movement of particles in and out of the cell. Cell membranes are Selectively permeable – the ability to allow molecules to pass through. Movement Across the Plasma Membrane • A few molecules move freely – Water, Carbon dioxide, Ammonia, Oxygen • Carrier proteins transport some molecules – Proteins embedded in lipid bi-layer – Fluid mosaic model – describes fluid nature of a lipid bi-layer with proteins Membrane Proteins 1. Channels or transporters – Move molecules in one direction 2. Receptors – Recognize certain chemicals Membrane Proteins 3. Glycoproteins – Identify cell type 4. Enzymes – Catalyze production of substances Cell Walls • Found in plants, fungi, & many protists • Surrounds plasma cell membrane • Helps cell maintain shape Cell Wall Differences • Plants – mostly cellulose • Fungi – contain chitin Cell Parts and Organelles Inside The Eukaryotic Cell Nucleus DNA Nucleolus Nuclear membrane Cytoplasm Endoplasmic Reticulum Ribosomes Mitochondria Golgi bodies Lysosomes Vacuoles Chloroplast Centrioles Cytoplasm • Gel-like fluid containing organelles • Supports the internal structures of all cells • Components of cytoplasm – Interconnected filaments & fibers – Fluid = cytosol – Organelles (not nucleus) – storage substances Cytoskeleton • Filaments & fibers • Made of 3 fiber types – Microfilaments – Microtubules – Intermediate filaments • 3 functions: – mechanical support – anchor organelles – help move substances A = actin, IF = intermediate filament, MT = microtubule Cilia & Flagella • Provide motility – ability to move • Cilia – Short – Used to move substances outside human cells • Flagella – Whip-like extensions – Found on sperm cells Cilia & Flagella Structure • Bundles of microtubules • With plasma membrane Centrioles • Pairs of microtubular structures • Found only in animal cells • Play a role in animal cell division Membranous Organelles • Functional components within cytoplasm • Bound by membranes Nucleus • Directs cell activities • Separated from cytoplasm by nuclear membrane (selectively permeable) • Contains genetic material – DNA DeoxyriboNucleic Acid • Contains the nucleolus – ribosomes (RNA) are stored and produced here. Nuclear Membrane • Surrounds the nucleus • Made of two layers • Selectively permeable – has pores that allow materials to enter and leave the nucleus • Also called the nuclear envelop DNA • Hereditary material • Chromosomes – DNA – Proteins – Form for cell division • Chromatin Chromosomes • In the nucleus • Made of tightly coiled DNA • Contain instructions for traits & characteristics Chromatin – uncoiled DNA Nucleolus • Most cells have 2 or more • Directs synthesis of RNA • Forms ribosomes Ribosomes • Each cell contains thousands • Make proteins • Found on ER & floating throughout the cell • Three types of RNA: mRNA- messenger tRNA- transfer rRNA- ribosomal Endoplasmic Reticulum • Helps move substances within cells • Network of interconnected membranes • Two types – Rough endoplasmic reticulum – Smooth endoplasmic reticulum Rough Endoplasmic Reticulum • Ribosomes attached to surface – Manufacture proteins (protein synthesis) – Not all ribosomes attached to rough ER • May modify proteins from ribosomes Smooth Endoplasmic Reticulum • No attached ribosomes • Has enzymes that help build molecules – Carbohydrates – Lipids Golgi Apparatus • Involved in synthesis of plant cell wall • Packaging & shipping station of cell Golgi Apparatus Function 1. Molecules arrive in vesicles 2. Vesicles fuse with Golgi membrane 3. Molecules may be modified by Golgi 4. Molecules pinched-off in separate vesicle 5. Vesicle leaves Golgi apparatus 6. Vesicles may combine with plasma cell membrane to secrete/release contents out of the cell. Lysosomes • Contain digestive enzymes • Recycling organelle of the cell • Functions – Aid in cell renewal – Break down old cell parts – Digests invaders Enzymes – proteins that speed up chemical reactions; used to break down larger substances. Vacuoles • Membrane bound storage sacs • More common in plants than animals • Helps plants maintain shape • Contents – Water – Food – wastes Energy Processing Organelles Types – Mitochondria (release energy) – Chloroplasts (store energy) Mitochondria • Have their own DNA • Bound by double membrane Mitochondria • Break down fuel molecules (cellular respiration) – Glucose – Fatty acids • Release energy – ATP Mitochondria • Stores and releases energy. (Powerhouse of the cell) • Cellular Respiration – the chemical reaction that releases energy (ATP) from carbohydrates and fats with the use of oxygen. • Cellular respiration begins in the cytoplasm and it is completed in the mitochondria. Chloroplast • Solar energy capturing organelle found in plant cells • Contains green pigment called chlorophyll • Photosynthesis occurs in chloroplast • Photosynthesis- the chemical reaction that converts CO2, water, and sunlight into food/glucose. Questions? Representative Animal Cell Animal Cell Nucleus Ribosome Mitochondria Cell membrane Nucleolus Endoplasmic reticulum Cytoplasm Golgi bodies Centrioles Vacuole Lysosome Representative Plant Cell Plant Cell Cell wall Nucleus Ribosome Cell membrane Mitochondria Nucleolus Lysosome Endoplasmic reticulum Cytoplasm Golgi bodies Vacuole Chloroplast Animal Cell VS Plant Cell Plant Cell Organelles Functions Cell membrane Selectively permeable, protective, fatty covering around all cells Cell wall Rigid outer covering that protects and supports Cytoplasm Mitochondria Ribosomes Chloroplasts Gel-like material inside all cells that supports internal cell structures, and the location of most chemical reactions Stores and releases large amounts of energy through a chemical reaction called cellular respiration make the proteins used by cells for growth, repair, reproduction, and break down or recycling of cell parts Green colored organelle that converts CO2, water, and sunlight into food (glucose) through photosynthesis Golgi bodies Package cellular substances into vesicles for transport Nucleus Largest organelle of the cell that regulates all cellular actives Endoplasmic reticulum Transport system of the cell, where proteins are synthesized Central Vacuole Stores unused cellular substances such as water and minerals Nucleolus Produces, stores, and releases RNA Animal Cell Organelles Functions Cell membrane Selectively permeable, protective, fatty covering around all cells Cytoplasm Gel-like material inside all cells that supports internal cell structures, and the location of most chemical reactions Mitochondria Stores and releases large amounts of energy through a chemical reaction called cellular respiration Ribosomes make the proteins used by cells for growth, repair, reproduction, and break down or recycling of cell parts Centrioles Help with animal cell reproduction Golgi bodies Package cellular substances into vesicles for transport Nucleus Largest organelle of the cell that regulates all cellular actives Endoplasmic reticulum Transport system of the cell, where proteins are synthesized Nucleolus Produces, stores, and releases RNA Cell Structure and Function • Brain Pop – Cell Structure and Function SCMS BrainPop Login Information: Username: schleymhs Password: schleymhsbp Biological Organization Levels of Biological Organization Levels of Biological Organization Levels of Biological Organization Atom Levels of Biological Organization Atom Levels of Biological Organization Atom Levels of Biological Organization Atom Levels of Biological Organization Atom Levels of Biological Organization Atom Organic Molecule Levels of Biological Organization Atom Organic Molecule Levels of Biological Organization Atom Organic Molecule Levels of Biological Organization Atom Organic Molecule Levels of Biological Organization Atom Organic Molecule Levels of Biological Organization Atom Organic Cell Molecule Organelle Levels of Biological Organization Atom Organic Cell Molecule Organelle Levels of Biological Organization Atom Organic Cell Molecule Organelle Levels of Biological Organization Atom Organic Cell Molecule Organelle Levels of Biological Organization Cell Atom Organic Cell Molecule Organelle Levels of Biological Organization Cell Atom Organic Cell Molecule Organelle Levels of Biological Organization Cell Atom Organic Cell Molecule Organelle Cell Levels of Biological Organization Cell Atom Organic Cell Molecule Organelle Cell Levels of Biological Organization Cell Atom Organic Cell Molecule Organelle Tissue Cell Levels of Biological Organization Cell Atom Organic Cell Molecule Organelle Tissue Cell Levels of Biological Organization Cell Atom Organic Cell Molecule Organelle Tissue Cell Levels of Biological Organization Cell Atom Organic Cell Molecule Organelle Tissue Cell - Levels of Biological Organization Cell Atom Organic Cell Molecule Organelle Tissue Organ Cell Levels of Biological Organization Cell Atom Organic Cell Molecule Organelle Tissue Organ Cell Levels of Biological Organization Cell Atom Organic Cell Molecule Organelle Tissue Organ Cell Levels of Biological Organization Cell Atom Organic Cell Molecule Organelle Tissue Organ Cell Levels of Biological Organization Cell Atom Organic Cell Molecule Organelle Organ System Tissue Organ Cell Levels of Biological Organization Cell Atom Organic Cell Molecule Organelle Organ System Tissue Organ Cell Levels of Biological Organization Cell Atom Organic Cell Molecule Organelle Organ System Tissue Organ Cell Levels of Biological Organization Cell Atom Organic Cell Molecule Organelle Organ System Many Systems Tissue Organ Cell Levels of Biological Organization Cell Atom Organic Cell Molecule Organelle Organism Organ System Tissue Organ Cell Levels of Biological Organization Cell Atom Organic Cell Molecule Organelle Organism Organ System Tissue Organ Cell “I’m Coach Blocker, Biology teacher” “I’m Coach Blocker, Biology teacher” “I am made of an enormous number of atoms” “I’m Coach Blocker, Biology teacher” “I am made of an enormous number of atoms” “Which come together to create molecules” “I’m Coach Blocker, Biology teacher” “I am made of an enormous number of atoms” “Which come together to create molecules” “Which can organize to create cell organelles” “I’m Coach Blocker, Biology teacher” “I am made of an enormous number of atoms” “Which come together to create molecules” “Which can organize to create cell organelles” “Many organelles can form a eukaryotic cell.” “I’m Coach Blocker, Biology teacher” “I am made of an enormous number of atoms” “Which come together to create molecules” “Which can organize to create cell organelles” “Many organelles can form a eukaryotic cell.” “Many specialized cells form tissues.” “I’m Coach Blocker, Biology teacher” “I am made of an enormous number of atoms” “Which come together to create molecules” “Which can organize to create cell organelles” “Many organelles can form a eukaryotic cell.” “Many specialized cells form tissues.” “Specialized tissues can form organs.” “I’m Coach Blocker, Biology teacher” “I am made of an enormous number of atoms” “Which come together to create molecules” “Which can organize to create cell organelles” “Many organelles can form a eukaryotic cell.” “Many specialized cells form tissues.” “Specialized tissues can form organs.” “Many organs can form an organ system.” “I’m Coach Blocker, Biology teacher” “I am made of an enormous number of atoms” “Which come together to create molecules” “Which can organize to create cell organelles” “Many organelles can form a eukaryotic cell.” “Many specialized cells form tissues.” “Specialized tissues can form organs.” “Many organs can form an organ system.” “Many organ systems working together can form organisms.” “I’m Coach Blocker, Biology teacher” I am made of an enormous number of atoms” “Which come together to create molecules” “Which can organize to create cell organelles” “Many organelles can form a eukaryotic cell.” “Many specialized cells form tissues.” “Specialized tissues can form organs.” “Many organs can form an organ system.” “Many organ systems working together can form organisms.” These are the levels of organization! Cell Specialization • Brain Pop – Cell specialization SCMS BrainPop Login Information: Username: schleymhs Password: schleymhsbp Cell Review CELL CITY Organelle City Analogy Organelle City Analogy Nucleus City Hall Cytoplasm Air, rain, and clouds Cell Membrane Mitochondria Power Company DNA, Chromosomes, Chromatin Mayor Chloroplast Solar Power Plant Lysosomes Food processing or recycling Plant Vacuole Warehouse Endoplasmic Reticulum Ribosomes Nucleolus City Limits Roads and Streets Construction Company City workers Plant Cell Cell wall Nucleus Ribosome Cell membrane Mitochondria Nucleolus Lysosome Endoplasmic reticulum Cytoplasm Golgi bodies Vacuole Chloroplast Animal Cell Nucleus Ribosome Mitochondria Cell membrane Nucleolus Endoplasmic reticulum Cytoplasm Golgi bodies Centrioles Vacuole Lysosome Chemical Equation for Cellular Respiration Reactants C6H12O6 + 6O2 Products ATP + 6CO2 + 6H2O Glucose Diatomic Energy Carbon Water dioxide oxygen Chemical Equation for Photosynthesis Reactants Products Sunlight + 6CO2+ 6H2O C6H12O6 + 6O2 Energy Carbon Water dioxide Glucose Diatomic oxygen Cellular Respiration vs Photosynthesis Products Reactants C6H12O6 + 6O2 ATP + 6CO2 + 6H2O Glucose Diatomic Energy Carbon Water dioxide oxygen Reactants Products Sunlight + 6CO2+ 6H2O C6H12O6 + 6O2 Energy Carbon Water dioxide Glucose Diatomic oxygen Cell Processes • Photosynthesis – the chemical process that converts light energy, carbon dioxide, and water into food for plants. Occurs in the chloroplast of plant cells. • Cellular Respiration – the chemical process of breaking down carbohydrates with oxygen to release the stored chemical energy. Occurs in the mitochondria. • Fermentation – the chemical process of breaking down carbohydrates without the use of oxygen. Occurs in the cytoplasm. Cellular Transport What are the two types of cellular transport? • Passive Transport (3 types) Diffusion Osmosis Facilitated Diffusion • Active Transport (3 types) Protein Pumps Endocytosis Exocytosis