6.3 Mendel and Heredity Section 6-3: “Mendel & Basic Heredity” Write everything that is underlined 6.3 Mendel and Heredity KEY CONCEPT Mendel showed that traits are inherited as definite, identifiable, units (genes), some of which are dominant over others. 6.3 Mendel and Heredity Mendel was the “Father” of Genetics. A. Genetics • The study of inheritance patterns = predictable variations between offspring of the same parents. • Traits are inherited characteristics. • Traits are inherited as definite units – later called “genes” • Some genes dominate others. • Mendel studied ordinary garden peas. 6.3 Mendel and Heredity Mendel’s data revealed patterns of inheritance. B. Mendel’s Experiments: He made some key decisions 1. He used “True-breeding” plants • Plants whose offspring always look like the parents 2. He “controlled” the breeding (fertilization) of plants 3. He observed seven“either-or” traits - like purple OR white flower color - TALL or short height - green or yellow pea color, etc. 6.3 Mendel and Heredity 3. Pea plant characteristics - Mendel Studied 7 “Either-or” Traits of Pea Plants – The traits included … - Pea Shape Pea Color Flower Color Pod Shape Pod Color Flower Position Plant Height (round or wrinkled) (yellow or green) (purple or white) (smooth or constricted) (yellow or green) (axial or terminal) (tall or short) 6.3 Mendel and Heredity Mendel’s data revealed patterns of inheritance. • True-breeding Plants and Fertilization – Pea plants have both male and female reproductive organs • Male gametes/sex cells (sperm) are called “pollen” • Female gametes/sex cells (eggs) – True-breeding plants “self-pollinate”, meaning fertilize themselves • Offspring are always identical to the parent (because the parent has just one type of gene for the trait) 6.3 Mendel and Heredity Mendel’s data revealed patterns of inheritance. Cross: Breeding 2 different plants together… (using pollen & eggs from separate plants) - Mendel cut away the male part of 1 parent and used pollen from a 2nd parent to fertilize it. - This is also Called “Cross-pollination” or “a cross” Mendel controlled the fertilization of his pea plants by removing the male parts, or stamens. He then fertilized the female part, or pistil, with pollen from a different pea plant. 6.3 Mendel and Heredity Cross: Produced 3 generations: P, F1, and F2 (P = parent; F = child) – P: Parent generation. 2 true-breeding plants were cross-pollinated, to produce the F1 generation – The F1 offspring (of the P’s) were self-pollinated and produced the F2 generation Mendel controlled the fertilization of his pea plants by removing the male parts, or stamens. He then fertilized the female part, or pistil, with pollen from a different pea plant. 6.3 Mendel and Heredity • F1 - ALL F1 offspring had purple flowers. - Mendel let the (all purple flower) F1 plants selfpollinate to produce the F2 generation. - What do you expect the F2’s to look like? 6.3 Mendel and Heredity • F2 - ¾’s of the F2 plants had purple flowers and ¼ had white flowers (see below) 6.3 Mendel and Heredity Results: Patterns. - Mendel observed patterns in the F1 and F2 generations. - What are these patterns? - Remember how the F1’s compared to the P’s… then, look below to see the F2 results. 6.3 Mendel and Heredity Results: Patterns • Pattern 1: – 100% of the F1 offspring looked like one of the parents • For example, all F1’s had purple flowers – none were white • Pattern 2: – The F2 offspring were mixed in each trait, 75% of one variation and 25% of the other • For example, 3 plants with purple flowers and 1 with white flowers • That’s a ratio of 75 to 25 (75:25), or 3:1 (3 to 1). 6.3 Mendel and Heredity Conclusions: Mendel made 4 1. Traits are inherited as discrete units (we call genes) “Law of Segregation” (has 2 conclusions): 2. Organisms inherit two copies of each gene, one from each parent. 3. The two copies segregate during gamete formation • Each copy goes to a different egg or sperm (Think of Meiosis and that gametes are haploid, having one copy of each chromosome) purple white 6.3 Mendel and Heredity Additional Conclusion? First, he had two questions: - Why were 100% of the F1’s purple (and none white)? - Why were just 75% of the F2’s purple (and 25% white)? - Purple seemed to “overpower” white…. Conclusion 4? 6.3 Mendel and Heredity Conclusion 4: Dominance. - Some inherited versions of a gene for a trait dominate the other(s)! Ex: For flower color trait, the purple flower gene dominates the white flower gene, so plants with a mix (“hybrids”) of one purple and one white gene, will have purple flowers, only. 6.3 Mendel and Heredity …test. This is only a test. Had this been a real …. Pea pod shapes are either Wrinkled or Round. Round is dominant (so wrinkled is recessive). (1) What would the pods of the offspring of a true-breeding Wrinkled-pod parent and a true-breeding Round-pod parent look like? (2) If two of these offspring were cross-bred, how many of their offspring would be Round? How many would be wrinkled? 6.3 Mendel and Heredity Answer…. (1) ALL of the offspring (F1’s) would be Round. (Each would receive 1 dominant (round) and 1 recessive (wrinkled) allele from their true-breeding parents. This is called “heterozygous” – a mix: “1 Round (R) & 1 wrinkled (r) allele”, or “Rr”) (2) Seventy-five percent (75%) of the F2 offspring would be Round and twenty-five percent would be wrinkled. (Each of the heterozygous F1 “rounds” (above) could give either a dominant or a recessive allele to an F2 offspring. - Does this blow your mind right in front of your face?) F2 Parents: Give either or Rr Rr R + r + R or r = RR or Rr R or r = RR or rr 6.3 Mendel and Heredity WHAT genes do the F2 offspring receive?! F1 (parents): Rr Give either or R r F2 (offspring): = = Rr + + (both heterozygous) R or r R or r RR or Rr Rr or rr = = ? pairs ? pairs (Four possible outcomes) RR (1 way) = homozygous dominant = Round peas Rr (2 ways) = heterozygous (dominant) = Round peas rr (1 way) = homozygous recessive = wrinkled peas Outcomes: ¾ Round and ¼ wrinkled 6.3 Mendel and Heredity Punnett Squares: We show the possible offspring combinations with a diagram called a Punnett Square PUNNETT SQUARES - We show the possible offspring combinations with a diagram called a “Punnett Square” 6.3 Mendel and Heredity Using Punnett Squares - Genes/alleles are represented by a capital letter for a dominant trait and a lower case for a recessive trait: - ie, round pea pods = R; wrinkled pea pods = r - Put one parent’s gene combinations across the top and one across the side of the square - Fill in the 4 boxes of the Punnett Square with the letters above and to the side 6.3 Mendel and Heredity Using Punnett Squares • Both parents have one Dominant and one recessive Allele for pod shape. - that’s called “Heterozygous” • Offspring - one of four (1/4) has two dominant alleles – That’s “Homozygous Dominant” • One of four (1/4) has two recessive alleles – That’s “Homozygous Recessive” • Two of four (2/4 = ½) have a mix of one dominant and one recessive – That’s “H “