Chapter 8 Outline: Mendel and Heredity The Origins of Genetics Mendel’s Studies of Characters Heredity Mendel’s Breeding Experiments Genetics Useful Features in Peas 1 2 3 Traits Expressed as Simple Ratios Hybrid Cross Step 1 True-breeding P generation Step 2 F1 generation Step 3 F2 generation Mendel’s Results Mendel’s Theory A Theory of Heredity Mendel’s Hypotheses 1. 2. alleles 3. dominant recessive 4. Mendel’s Findings in Modern Terms Homozygous Heterozygous Genotype Phenotype The Laws of Heredity The Law of Segregation The Law of Independent Assortment Studying Heredity Punnett Squares One Pair of Contrasting Traits Monohybrid Cross Dihybrid Cross Determining Unknown Genotypes Test cross Outcomes of Crosses Probability Probability of a Specific Allele in a Gamete Probability of the Outcome of a Cross Inheritance of Traits Pedigree Autosomal or Sex-linked? Sex-linked genes Dominant of Recessive? Heterozygous or Homozygous? Complex Patterns of Heredity Complex Control of Characters Characters Influenced by Several Genes Polygenic inheritance Intermediate Characters Incomplete dominance Characters Controlled by Genes With Three or More Alleles Multiple Alleles Characters with Two Forms Displayed at the Same Time Codominance Characters Influenced by the Environment Genetic Disorders Sickle Cell Anemia Cystic Fibrosis (CF) Hemophilia Huntington’s Disease (HD) Treating Genetic Disorders Gene Therapy