Finding Reliable Clinical Information Online An Introduction Nancy Clark, M.Ed. Director of Medical Informatics Education FSU College of Medicine http://www.med.fsu.edu/informatics/MedicalReferences.asp Summer 2010 1 Major Competency Students will • Demonstrate the ability to acquire new data and information and to critically appraise its validity and applicability. Summer 2010 2 Objectives of Session Students will • Demonstrate ability to locate quality clinical information on the web utilizing a variety of strategies • Assess the reliability and validity of clinical information found using search engines on the web • Begin to utilize the FSU COM virtual library resources to locate medical information for clinical decision support [Old and new] Summer 2010 3 Resources http://www.med.fsu.edu/informatics/ Medical References • PowerPoint • Assessing the Validity of Online Medical • • Information Decision Support Using Drug Resources Summer 2010 4 Review What is the most efficient, unbiased way to keep up to date? 1. Go to conferences 2. Read 20-30 journal articles a week 3. Look up answers to clinical questions when they occur in a reliable, current resource Summer 2010 5 In the Beginning… Journals Text Books Peer Reviewed Summer 2010 Pocket Manuals Drug Info Note Cards 6 “Textbooks don’t smell as their contents rot, so readers will need to develop alternative crap detectors to avoid poisoning their minds and robbing their patients of current best care.” David Sackett, MD Pioneer of Evidence Based Medicine (EBM) The half life of medical information is estimated at 5 years. Summer 2010 7 21st Century Medical Information Journals Text Books Pocket Manuals Drug Info Note Cards Summer 2010 8 Here is the Problem… Which of these sites are accurate? Which of these sites are reliable? Which of these sites are up to date? Which of these sites are not biased? Summer 2010 9 Assessing the Validity of Information on the Web AMA Guidelines for Medical and Health Information Sites on the Internet Health on the Net Code of Conduct HON Summer 2010 10 Assessing the Validity of Information on the Web Site ownership/domain • Gov – – – – – – CDC AHRQ NLM.NIH DHHS FDA States fl.us • Edu – Medical Centers Summer 2010 • Org – Associations • AAFP • ACP • ACOG – Disease orgs • ADA • ALA • Com – Commercial 11 Assessing the Validity of Information on the Web Site ownership/domain Contributors listed, credentials, contact info Highly referenced, linked to primary literature • MEDLINE Abstracts/Journal Articles • Proceedings from scientific meetings Timeliness: date posted, revised Viewer access, payment and privacy Funding and sponsorship Summer 2010 12 Wikipedia List 5 ways Wikipedia does not fit the criteria as a reliable site. Summer 2010 13 Exercise Search Google for treatment of back pain Rate the first 20 hits • Sponsor? Advertisements? • Audience? • Authors? • Links? • Date Revised? Do advanced search limit to .gov domain and compare results Search for prostate cancer screening Summer 2010 14 Types of Information Found Free on the Web Information for/by students Information for/by patients Information for/by clinicians Information for/by researchers Sales pitches, ads Quacks who want to sell something Unproven, unsubstantiated nonsense Summer 2010 15 Assessing the Validity of Information on the Web Library subscription resource = reliable Summer 2010 16 Be Skeptical You will be taught the principles of critical review of the literature in your second year along with Evidence Based Medicine (EBM) Summer 2010 17 What Kind of Question Do I Have? Basic science or background question? Clinical question? • What is an olecranon? • What are the risk factors for hypertension? • Which is better for diagnosing pneumonia: x-ray, • • CT or MRI? How should I treat otitis media? How much does amoxicillin cost? Summer 2010 18 Answering a Background Question Searching most efficient Google/Wikipedia (assess the validity) Use Medical Dictionary Basic Science Textbooks • Access Medicine • Thieme Summer 2010 19 Searching with Google $ubscription Free Web Based Medical Information Google Search Summer 2010 20 Your eBookshelf Summer 2010 21 Medical Dictionaries Stedman’s is at eMedicine, in PEPID Dorland’s at Merck Summer 2010 22 Exercises for Practice Using Stedman’s Medical Dictionary Look up: dyspnea teratogenic epistaxis cyanosis • eMedicine online • PEPID online and PDA Summer 2010 nephrolithiasis iatrogenic 23 Books on the Library Web Page Summer 2010 24 When to Use eBooks versus Quick References Background information on topic • Basic science question instead of disease specific question Detailed information/explanations versus bottom line Lots of time versus short on time Zebras versus common problems Summer 2010 25 WebFeat Search Searches Library Resources Pick the type of resources to search Groups by resource Uses resource search engine Summer 2010 26 New Website Searches Multi-Search = Webfeat Changing to SerialSolutions 360, August 2010 Only eBooks and Patient Education Summer 2010 27 Access Medicine Best selection of all basic science books Combined with good clinical medicine books Search productive Summer 2010 28 Answering Clinical Questions At the Point of Care Summer 2010 29 Answering Clinical Questions Quickest method: Browse to specific resource Requires: knowing the content of sites/resources Starting point: Library web page or your handheld (iPod or cell phone) Learn to use subscription resources Summer 2010 30 Current Library Web Site Summer 2010 (Sum 2010) 31 New Library Webpage Summer 2010 32 Access Issues IP address verification Limited simultaneous users Special URL issues Bottom Line • Use links on Library Homepage Summer 2010 33 Off Campus Access IP authentication Proxy server – EZProxy FSU COM ID and password Use links on library page Summer 2010 34 Current Site Summer 2010 - New Site 35 Primary Resources of the Maguire Medical Library Summer 2010 36 Summer 2010 37 Differential Diagnosis Tools DxPlain PEPID Summer 2010 38 Differential Diagnosis Tools Enter symptoms or chief complaint PEPID *** eMedicine ** Access Medicine’s • Get a differential • Get more info on disease DxPlain ***** • Harvard • Allows for multiple • symptoms and lab results Drawback: Slow Summer 2010 • Multiple symptoms • Lab Results • Age, gender, duration • Diagnosaurus* (DDX tab) 39 Exercises for Practice Using DxPlain or PEPID Patient 35 yr old female Chief complaint – fatigue, duration 2 months • Other symptoms: throat pain, cold intolerance, weight gain, bradycardia, and constipation, Differential? • Add lab: Summer 2010 elevated TSH 40 Drug Information Epocrates Online PEPID Harrison’s Practice Summer 2010 41 Epocrates Online Rx, OTC and Alternative medicines by brand name, generic, and by class Formularies Drug Interaction tool Disease reference, pill identifier, medical calculators, tables Constantly updated Summer 2010 42 Epocrates Drug Interaction MultiCheck Tool Add all the drugs on the patients medications list (Rx, OTC, Alt) plus drug considering Look to see if any interactions What is the severity of interaction PEPID CRC Suite Rx, OTC and Alternative medicines by brand name, generic, and by class Drug Interaction tool DDx, Disease reference, Lab manual, medical calculators, clerkships, images Constantly updated Summer 2010 44 PEPID Drug Interaction Tool Select all drugs on list Say Done Click Interactions Click specific interaction to read details Summer 2010 45 Exercises for Practice Using Epocrates Online How should you prescribe acyclovir for chicken pox in an immunocompromised patient? (dose) How much do 9 (50 mg) tablets of Imitrex cost? (common migraine drug) Are there any drug interactions between Lexapro, Lortab, Xanax and Zocor? Summer 2010 46 Disease Quick References DynaMed (Web and PDA) eMedicine (Web and PDA) Harrison’s Practice (Web and PDA) Epocrates Dx PEPID Summer 2010 47 Types of Questions Best Answered by Disease Quick References Description/background Epidemiology Diagnosis Treatment Ongoing management Prognosis/outcomes Prevention Summer 2010 Bottom Line 48 DynaMed Most comprehensive disease reference Summarizes all the latest research on topic Very detailed Well organized Links out to full text articles if more details needed Includes both diseases and symptoms like chest pain PDA and Online Summer 2010 49 DynaMed Organization: Includes History and Physical sections (why am I asking these questions) Expand or collapse sections Use CTRL-F to search page Summer 2010 50 Exercises Dynamed Exercise for Practice Using Dynamed -- Question: What is the typical history of present illness for someone with SARS? Type in SARS or use alphabetical listing Explode History Summer 2010 51 Use FireFox eMedicine Moderate amount of detail and information Several monographs on one topic by different specialties Google searches it Now owned by WebMD/Medscape. Suggest registering. One of Student’s favorite iPhone version in Medscape Summer 2010 52 eMedicine Monographs Subscription eliminates ads found on free Medscape site One long page of information Navigation clunky, inconsistent CTRL-F Summer 2010 53 Exercises for Practice Using eMedicine - Question: What is the functional anatomy when you have a Rotator Cuff Injury? Search or browse to Rotator Cuff Injury. Use Sports Medicine article. Select Introduction Summer 2010 54 Harrison’s Practice Internal Medicine focus Linked to Access Medicine content Has drug information from GoldStandard Nice navigation on left side PDA and Online Summer 2010 55 Exercises for Practice Using DynaMed, eMedicine, Epocrates and/or Harrison’s Practice: • Develop a scenario for CSSC practice • Complete form provided • (optional) Pick from diseases top 10 DDx in primary • • • care or top 20 diagnoses seen by students Complete electronically (form on Blackboard) Change file name to your name (John_Doe.doc) Upload to Blackboard Assignments Tab on D101 BB by Friday the 7/23/09, by midnight Summer 2010 56 Top 10 Chief Concerns 1. 2. 3. 4. 5. Cough Fatigue Low Back Pain Fever Dyspnea 6. 7. 8. 9. 10. Generalized Abdominal Pain Headache Vertigo Chest Pain Edema Ponka, D., et al. Top Ten Differential Diagnoses in Primary Care. [Web Resource] U of Ottowa. 2006. Accessed at www.familymedicine.uottawa.ca/ Summer 2010 57 Top 20 Diseases Recorded by FSU CoM Students in 3 1. Hypertension 2. Depression 3. Hyperlipidemia 4. Diabetes Type 2 5. Bipolar disorder 6. Anxiety disorder 7. Cold/URI 8. ADHD 9. Otitis media 10. Schizophrenia Summer 2010 11. 12. 13. 14. 15. 16. 17. 18. 19. 20. rd year Clerkships Obesity Gall Bladder disease GERD Asthma Sinusitis Substance abuse COPD Coronary Artery Disease Peripheral vascular disease Pneumonia 58 iPod/iPhone/iPad Versions • • Clinical Evidence DynaMed Epocrates Essentials Essential Evidence+ Harrison’s Practice PEPID Geriatrics at Your Fingertips Free resources • ePSS USPSTF Tool • Mobile Merck • Medicus Medscape PDAs to be distributed in August 25-27 Summer 2010 59 Review Name three things you should look for in a web site with medical information that would make you feel more confident about the content of that website. What resources are going to be the most accurate, reliable, and up to date? Name a library drug reference, a differential diagnosis resource, and a disease quick reference Summer 2010 60