Mitosis • Cell Cycle Period of time from one division to the next Cell Cycle Unicellular division results in formation of new individuals of the species Multicellular division results in replacement of old or damaged cells Mitosis Process by which the nucleus divides while maintaining number of chromosomes Cytokinesis Division of the cytoplasm Asexual Reproduction Reproduction that only involves one parent so therefore no special reproductive organs are needed Chromatin Nuclear DNA wound around proteins known as histones Chromosomes Condensed rolls of chromatin that are able to be seen during mitosis (rod-like structures) There are 5 phases in MITOSIS Interphase Prophase Metaphase Anaphase Telophase Interphase Known as “resting phase” •Cells grow in size by producing more nucleic acids, proteins, and cellular organelles •Chromosomes make copies of themselves, but they can’t be •seen •Nucleus of the cell is contained within the nuclear envelope •Centrioles are present and duplicate themselves Prophase •Double chromosomes become visible - Chromatid •Chromosomes are 2 sister chromatids connected by a centromere Sister Chromatids Centromere •At the beginning, centrioles move to opposite poles •Aster (star shaped fibers) extend = microtubules •Spindle fibers attach (to centromere to pull away chromatids to opposite sides of the cell) •By the end, the nuclear envelope and nucleus have disappeared DON’T DRAW EARLY LATE Metaphase •Centromeres line up on the equator (middle= metaphase plate) •By the end, the centromeres divide and pull the daughter chromosomes to opposite sides of the cell •Half of each chromosome goes to the opposite side of the cell Anaphase •Daughter chromosomes move to opposite sides of cell (poles) •Movement is accomplished by the microtubules •Movement occurs by shortening of the microtubules Telophase •Chromosomes uncoil and return to previous shape (threadlike) •Nuclear membrane and nuclei reform NOTE: Cytokinesis begins during late anaphase and finishes during telophase She had it coming!! An easy way to remember the order of the phases in mitosis is to think: I PUNCHED MY AUNT TILLY!! Same as mitosis in animals except: • Plants have no centrioles – spindle fibers take their place • Asters do not form • Cell wall does not pinch because it is too rigid • Cell plate divides the cell into two