Mitosis Flashcards Interphase • Draw: • Label: – Plasma membrane – Nucleus – DNA • Interphase is not part of mitosis • This is when the cell is doing its “everyday” job and getting ready for mitosis • Cell grows • Copies DNA Prophase • Draw: • Label: – Plasma membrane – Nucleus – Chromosomes – Centromeres – Spindle Fibers – Centrosome • Beginning of mitosis • DNA compacts into chromosomes • Centrosomes appear and begin to move to opposite ends of cell making the poles of the cell • The nuclear envelope breaks down • The mitotic spindle forms. It is made up of spindle fibers attached to each centrosome Metaphase • Draw: • Label: – Plasma membrane – Chromosomes – Centromeres – Spindle Fibers – Centrosome – Metaphase Plate • Sister chromatids attach to the spindle fibers at the centromere. • Each centromere has two kinetochores that attach to the spindle fibers, one from each centrosome • This causes the chromosomes to line up on the metaphase plate Anaphase • Draw: • Label: – Plasma membrane – Chromosomes – Centromeres – Spindle Fibers – Centrosome • Sister Chromatids separate and begin to move to opposite ends of the cell • The centrosomes shorten the spindle fibers dividing the sister chromosomes and bringing them to opposite side of the cell • Each chromatid is now considered a new chromosome Telophase • Draw: • Label: – Plasma membrane – Chromosomes – Nuclei (pleural) – Centrosome • Begins when the new chromosomes reach the centrosome • The spindle fibers break down • Two new nuclei form and the nuclear envelope forms around the chromosomes at each pole of the cell • Chromosomes appear as chromatin • Cytokinesis occurs