Integumentary System SAP2. Students will analyze the interdependence of the integumentary, skeletal, and muscular systems as these relate to the protection, support and movement of the human body. a. Relate the structure of the integumentary system to its functional role in protecting the body and maintaining homeostasis. EQ: What role does the integumentary system play in protecting the body and maintaining homeostasis? Cutaneous Membranes 1) Cutaneous – (skin); only epithelial membrane that is dry Integumentary System ► Most roles are protective ► Helps maintain homeostasis ► Insulates body ► Keeps water and molecules in body ► Protects organs from bumps, cuts, etc. Make-up of epidermis ► Epidermis has no blood supply (avascular) ► Most cells are keratinocytes Produce keratin (tough fibers which make skin tough but pliable) ► Basement Stratum Basale membrane of epidermis ► Vascularized ► Constantly undergoing mitosis ► By the time cells reach the surface, they are dead. Melanin ► Cells in stratum basale take in melanocytes (cells produce pigment) ► Melanin = body’s natural sunscreen Dermis ► Layer directly beneath the epidermis ► Highly Vascularized ► Connective tissue Make-up of Dermis ► Mostly collagen and elastic fibers ► Fibers bind with water and keep skin hydrated ► Fibers decrease with age, and skin sags Deep to the Dermis ► Subcutaneous layer Also called hypodermis Adipose tissue Absorbs impact from bumps, protects organs; insulation Skin Cancer ► Melanin serves to protect cellular DNA from ultraviolet light ► When damage is done to DNA, cancer can occur ► Basal Cell carcinoma (least malignant) ► Squamous cell carcinoma ► Melanoma – darkened blotches Cancer of the melanocyte Papillary Layer ► Upper dermal region ► Protrusions into epidermis called dermal papillae ► Nourishes epidermis Also in Papillary Layer ► Meissner’s corpuscles – sensory receptors (touch) ► Pain receptors ► Papillary pattern is genetic, and forms fingerprint Reticular Layer ► Deep layer to papillary ► Contains blood vessels, sweat glands and oil glands. ► Phagocytes prevent bacterial intrusion Sweat Glands ► Controlled system ► Two by nervous types ► 1) Eccrine ► 2)Appocrine Sebaceous Glands ► Oil Glands Ducts usually empty into a hair follicle Secretes sebum Sebum keeps skin moist and pliable Also produces acidic compounds that kill bacteria Problems with oil glands ► Clogged oil gland becomes whitehead ► As whitehead oxidizes, it becomes darker (blackhead) ► Acne – infection of oil gland ► Seborrhea- “cradle cap”